LanCLs add glutathione to dehydroamino acids generated at phosphorylated sites in the proteome

Cell - Tập 184 - Trang 2680-2695.e26 - 2021
Kuan-Yu Lai1, Sébastien R.G. Galan2, Yibo Zeng2,3,4, Tianhui Hina Zhou1, Chang He5, Ritu Raj2, Jitka Riedl2, Shi Liu5, K. Phin Chooi2, Neha Garg1, Min Zeng6, Lyn H. Jones7, Graham J. Hutchings3,8, Shabaz Mohammed2,4, Satish K. Nair1, Jie Chen6, Benjamin G. Davis2,4, Wilfred A. van der Donk1,5
1Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA
2Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Mansfield, Oxford OX1 3TA, UK
3UK Catalysis Hub, Research Complex at Harwell, Rutherford Appleton Laboratory, Harwell, Oxford OX11 0FA, UK
4The Rosalind Franklin Institute, Oxfordshire OX11 0FA, UK
5Department of Chemistry and Howard Hughes Medical Institute, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA
6Department of Cell and Developmental Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA
7Dana-Farber Cancer Institute, 360 Longwood Avenue, Boston, MA 02115, USA
8Cardiff Catalysis Institute, School of Chemistry, Cardiff University, Cardiff CF10 3AT, UK

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Tập 184

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