Developmental and Activity-Dependent Expression of LanCL1 Confers Antioxidant Activity Required for Neuronal Survival

Andersen, 2004, Oxidative stress in neurodegeneration: cause or consequence?, Nat. Med., 10, S18, 10.1038/nrn1434 Bauer, 2000, Characterization of p40/GPR69A as a peripheral membrane protein related to the lantibiotic synthetase component C, Biochem. Biophys. Res. Commun., 275, 69, 10.1006/bbrc.2000.3260 Brakeman, 1997, Homer: a protein that selectively binds metabotropic glutamate receptors, Nature, 386, 284, 10.1038/386284a0 Brennan, 2009, NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation, Nat. Neurosci., 12, 857, 10.1038/nn.2334 Carlsson, 1995, Mice lacking extracellular superoxide dismutase are more sensitive to hyperoxia, Proc. Natl. Acad. Sci. USA, 92, 6264, 10.1073/pnas.92.14.6264 Chatterjee, 2005, Biosynthesis and mode of action of lantibiotics, Chem. Rev., 105, 633, 10.1021/cr030105v Cheng, 1995, PDGFs protect hippocampal neurons against energy deprivation and oxidative injury: evidence for induction of antioxidant pathways, J. Neurosci., 15, 7095, 10.1523/JNEUROSCI.15-11-07095.1995 Chung, 2007, Identification of lanthionine synthase C-like protein-1 as a prominent glutathione binding protein expressed in the mammalian central nervous system, Biochemistry, 46, 3262, 10.1021/bi061888s Coyle, 1993, Oxidative stress, glutamate, and neurodegenerative disorders, Science, 262, 689, 10.1126/science.7901908 Crunkhorn, 2012, Deal watch: Abbott boosts investment in NRF2 activators for reducing oxidative stress, Nat. Rev. Drug Discov., 11, 96, 10.1038/nrd3655 Czerwinski, 1996, Busulfan conjugation by glutathione S-transferases alpha, mu, and pi, Drug Metab. Dispos., 24, 1015 Dalle-Donne, 2009, Protein S-glutathionylation: a regulatory device from bacteria to humans, Trends Biochem. Sci., 34, 85, 10.1016/j.tibs.2008.11.002 Finkel, 2000, Oxidants, oxidative stress and the biology of ageing, Nature, 408, 239, 10.1038/35041687 Flavell, 2008, Signaling mechanisms linking neuronal activity to gene expression and plasticity of the nervous system, Annu. Rev. Neurosci., 31, 563, 10.1146/annurev.neuro.31.060407.125631 Habig, 1981, Assays for differentiation of glutathione S-transferases, Methods Enzymol., 77, 398, 10.1016/S0076-6879(81)77053-8 Hayes, 1995, The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance, Crit. Rev. Biochem. Mol. Biol., 30, 445, 10.3109/10409239509083491 Hayes, 1999, Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defence against oxidative stress, Free Radic. Res., 31, 273, 10.1080/10715769900300851 Ho, 2004, Mice lacking catalase develop normally but show differential sensitivity to oxidant tissue injury, J. Biol. Chem., 279, 32804, 10.1074/jbc.M404800200 Ikonomidou, 2011, Neuronal death and oxidative stress in the developing brain, Antioxid. Redox Signal., 14, 1535, 10.1089/ars.2010.3581 Kamioka, 1996, Spontaneous periodic synchronized bursting during formation of mature patterns of connections in cortical cultures, Neurosci. Lett., 206, 109, 10.1016/S0304-3940(96)12448-4 Kondo, 2013, Modeling Alzheimer’s disease with iPSCs reveals stress phenotypes associated with intracellular Aβ and differential drug responsiveness, Cell Stem Cell, 12, 487, 10.1016/j.stem.2013.01.009 Landlinger, 2006, Myristoylation of human LanC-like protein 2 (LANCL2) is essential for the interaction with the plasma membrane and the increase in cellular sensitivity to adriamycin, Biochim. Biophys. Acta, 1758, 1759, 10.1016/j.bbamem.2006.07.018 Lyford, 1995, Arc, a growth factor and activity-regulated gene, encodes a novel cytoskeleton-associated protein that is enriched in neuronal dendrites, Neuron, 14, 433, 10.1016/0896-6273(95)90299-6 Massaad, 2011, Reactive oxygen species in the regulation of synaptic plasticity and memory, Antioxid. Redox Signal., 14, 2013, 10.1089/ars.2010.3208 Mitchell, 1997, Quantitative profiling of tissue- and gender-related expression of glutathione S-transferase isoenzymes in the mouse, Biochem. J., 325, 207, 10.1042/bj3250207 Mugoni, 2013, Ubiad1 is an antioxidant enzyme that regulates eNOS activity by CoQ10 synthesis, Cell, 152, 504, 10.1016/j.cell.2013.01.013 Muller, 2007, Trends in oxidative aging theories, Free Radic. Biol. Med., 43, 477, 10.1016/j.freeradbiomed.2007.03.034 Nyström, 2005, Role of oxidative carbonylation in protein quality control and senescence, EMBO J., 24, 1311, 10.1038/sj.emboj.7600599 Papadia, 2008, Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses, Nat. Neurosci., 11, 476, 10.1038/nn2071 Ratan, 1995, Apoptotic death in an in vitro model of neuronal oxidative stress, Clin. Exp. Pharmacol. Physiol., 22, 309, 10.1111/j.1440-1681.1995.tb02006.x Reaume, 1996, Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury, Nat. Genet., 13, 43, 10.1038/ng0596-43 Rossé, 1998, Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c, Nature, 391, 496, 10.1038/35160 Sharma, 2004, Antioxidant role of glutathione S-transferases: protection against oxidant toxicity and regulation of stress-mediated apoptosis, Antioxid. Redox Signal., 6, 289, 10.1089/152308604322899350 Sheehan, 2001, Structure, function and evolution of glutathione transferases: implications for classification of non-mammalian members of an ancient enzyme superfamily, Biochem. J., 360, 1, 10.1042/bj3600001 Skaper, 1998, Neurotrophins rescue cerebellar granule neurons from oxidative stress-mediated apoptotic death: selective involvement of phosphatidylinositol 3-kinase and the mitogen-activated protein kinase pathway, J. Neurochem., 70, 1859, 10.1046/j.1471-4159.1998.70051859.x Smiley, 1991, Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1, Proc. Natl. Acad. Sci. USA, 88, 3671, 10.1073/pnas.88.9.3671 Soriano, 2011, Neuronal activity controls the antagonistic balance between peroxisome proliferator-activated receptor-γ coactivator-1α and silencing mediator of retinoic acid and thyroid hormone receptors in regulating antioxidant defenses, Antioxid. Redox Signal., 14, 1425, 10.1089/ars.2010.3568 St-Pierre, 2006, Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators, Cell, 127, 397, 10.1016/j.cell.2006.09.024 Stranahan, 2012, Recruiting adaptive cellular stress responses for successful brain ageing, Nat. Rev. Neurosci., 13, 209, 10.1038/nrn3151 Ueno, 1997, Bicuculline and gabazine are allosteric inhibitors of channel opening of the GABAA receptor, J. Neurosci., 17, 625, 10.1523/JNEUROSCI.17-02-00625.1997 Yakes, 1997, Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress, Proc. Natl. Acad. Sci. USA, 94, 514, 10.1073/pnas.94.2.514 Zhang, 1993, Basic FGF, NGF, and IGFs protect hippocampal and cortical neurons against iron-induced degeneration, J. Cereb. Blood Flow Metab., 13, 378, 10.1038/jcbfm.1993.51 Zhang, 2009, Structure of human lanthionine synthetase C-like protein 1 and its interaction with Eps8 and glutathione, Genes Dev., 23, 1387, 10.1101/gad.1789209 Zhong, 2012, Lanthionine synthetase C-like protein 1 interacts with and inhibits cystathionine β-synthase: a target for neuronal antioxidant defense, J. Biol. Chem., 287, 34189, 10.1074/jbc.M112.383646