Design, synthesis, and evaluation of fluoroquinolone derivatives as microRNA-21 small-molecule inhibitors

Journal of Pharmaceutical Analysis - Tập 12 - Trang 653-663 - 2022
Yuan-Yuan Hei1,2, Si Wang3,2, Xiao-Xiao Xi1, Hai-Peng Wang4, Yuanxu Guo3,2, Minhang Xin1,2, Congshan Jiang3,2, Shemin Lu3,2, San-Qi Zhang1,2
1Department of Medicinal Chemistry, School of Pharmacy, Xi'an Jiaotong University Health Science Center, Xi'an, 710061, China
2Key Laboratory of Environment and Genes Related to Diseases (Xi'an Jiaotong University), Ministry of Education, Xi'an, 710061, China
3Institute of Molecular and Translational Medicine (IMTM), and Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, 710061, China
4Department of Medical Oncology, Shaanxi Provincial People's Hospital, Xi'an 710068, China

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