Design, synthesis, and biological evaluation of novel somatostatin receptor subtype-2 agonists: Optimization for potency and risk mitigation of hERG and phospholipidosis
Tài liệu tham khảo
(a) Fleseriu M. Clinical efficacy and safety results for dose escalation of somatostatin receptor ligands in patients with acromegaly. Pituitary 2011, 14, 184-193.
(b) Zahr R, Fleseriu M. Updates in Diagnosis and Treatment of Acromegaly. European Endocrinol 2018, 14, 57-61.
Netzer, 2001, Screening lead compounds for QTinterval prolongation, Drug Discovery Today, 6, 78, 10.1016/S1359-6446(00)01602-0