World Journal of Surgical Oncology

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Vitamin K1 enhances sorafenib-induced growth inhibition and apoptosis of human malignant glioma cells by blocking the Raf/MEK/ERK pathway
World Journal of Surgical Oncology - Tập 10 - Trang 1-7 - 2012
Wei Du, Jing-ru Zhou, Dong-liang Wang, Kai Gong, Qing-jun Zhang
The combined effects of anticancer drugs with nutritional factors against tumor cells have been reported previously. This study characterized the efficacy and possible mechanisms of the combination of sorafenib and vitamin K1 (VK1) on glioma cell lines. We examined the effects of sorafenib, VK1 or their combination on the proliferation and apoptosis of human malignant glioma cell lines (BT325 and ...... hiện toàn bộ
Mô tả về tình trạng carcinomatosis ổ bụng do khối u carcinoid ruột non Dịch bởi AI
World Journal of Surgical Oncology - Tập 4 - Trang 1-5 - 2006
Gonzalo Gutierrez, Ian R Daniels, Ana Garcia, Jose M Ramia
Carcinomatosis ổ bụng do khối u carcinoid đường tiêu hóa là hiện tượng hiếm gặp và việc quản lý lâu dài cũng như tiên lượng chưa được xác định rõ ràng. Lịch sử tự nhiên của nó khác với adenocarcinoma đường tiêu hóa, mặc dù khả năng xâm lấn các hạch bạch huyết khu vực và phát tán di căn xa có thể làm cho việc quản lý trở nên phức tạp hơn. Mặc dù sự phát triển của carcinomatosis ít được báo cáo, như...... hiện toàn bộ
#carcinomatosis ổ bụng #khối u carcinoid #bệnh lý #hóa trị #phẫu thuật
Castleman's disease in the head of the pancreas: report of a rare clinical entity and current perspective on diagnosis, treatment, and outcome
World Journal of Surgical Oncology - Tập 5 - Trang 1-6 - 2007
Hongbei Wang, Rosemary L Wieczorek, Michael E Zenilman, Fidelina Desoto-Lapaix, Bimal C Ghosh, Wilbur B Bowne
Castleman's disease of the pancreas is a very rare condition that may resemble more common disease entities as well as pancreatic cancer. Here we report the case of a 58-year-old African American male with an incidentally discovered lesion in the head of the pancreas. The specimen from his pancreaticoduodectomy contained a protuberant, encapsulated mass, exhibiting microscopic features most consis...... hiện toàn bộ
Overexpression of DSCR1 prevents proliferation and predicts favorable prognosis in colorectal cancer patients
World Journal of Surgical Oncology - Tập 19 - Trang 1-10 - 2021
Wen-Xiang Li, Jia-Jia Zheng, Gang Zhao, Chen-Tao LYU, Wei-Qi Lu
Down syndrome critical region 1 (DSCR1) is associated with carcinogenesis and tumor growth in several types of malignancy. However, little is known about the role of DSCR1 in CRC progression. The present study aimed to elucidate the clinicopathological significance, prognostic, and function roles of DSCR1 in CRC. Firstly, we analyzed DSCR1 expression in 58 paired CRC samples and Oncomine database....... hiện toàn bộ
Combined endocrine and exocrine tumours of the pancreas
World Journal of Surgical Oncology - Tập 5 - Trang 1-4 - 2007
Ahmed Alzaraa, Valeri Udom, Husam Mousa, Abdulhalem Alzein, Abduljalil Benhamida, Neha Dalal
Cystic neoplasms of the pancreas comprise 10%–15% of pancreatic cystic lesions, with the serous cystadenoms being the commonest. The association of exocrine and endocrine tumours of the pancreas unrelated to Von Hipple Lindau disease is very rare. Very few cases have been reported in the literature. We present another case of both these tumours in one patient. A female patient was seen in the surg...... hiện toàn bộ
Significance of bile culture surveillance for postoperative management of pancreatoduodenectomy
World Journal of Surgical Oncology - Tập 17 Số 1 - 2019
Keizō Sugimachi, Tomohiro Iguchi, Yohei Mano, Masaru Morita, Masaki Mori, Yasushi Toh
Abstract Background The management of infectious complications is important in pancreatoduodenectomy (PD). We sought to determine the significance of preoperative surveillance bile culture in perioperative management of PD. Methods This study enrolled 69 patients who ...... hiện toàn bộ
Retroperitoneal Castleman’s disease: advocating a multidisciplinary approach for a rare clinical entity
World Journal of Surgical Oncology - Tập 12 - Trang 1-7 - 2014
Austin D Williams, Adriana Sanchez, Jun Steve Hou, Rene Rothstein Rubin, Mark E Hysell, Blake D Babcock, Mohammad F Shaikh, Michael S Weingarten, Wilbur B Bowne
Castleman’s disease is a rare and poorly understood disease entity that may resemble more common conditions and represents a clinical challenge to the treating surgeon. In this report, we describe a case of a 61-year-old Caucasian woman with a symptomatic retroperitoneal mass. The specimen obtained from her resection contained a protuberant encapsulated mass, exhibiting microscopic features consis...... hiện toàn bộ
A retrospective comparative analysis of elderly and younger patients undergoing pulmonary resection for stage I non-small cell lung cancer
World Journal of Surgical Oncology - Tập 14 Số 1 - 2015
Byungjoon Park, Genehee Lee, Hong Kwan Kim, Yong Soo Choi, Jae Ill Zo, Young Mog Shim, Jhingook Kim
let-7b and let-7c are determinants of intrinsic chemoresistance in renal cell carcinoma
World Journal of Surgical Oncology - Tập 13 - Trang 1-8 - 2015
Jingtao Peng, Ren Mo, Jian Ma, Jie Fan
Renal cell carcinoma (RCC) is characterized by inherent resistance to chemotherapy. Earlier studies demonstrated that microRNAs (miRNAs) might be involved in the chemosensitivity of cancers. MicroRNA let-7, a putative tumor suppressor, is dysregulated in many cancers. Our study aims to investigate the exact role of let-7 in chemotherapy sensitivity of 5-fluorouracil (5-FU) in RCC. The clinical sig...... hiện toàn bộ
Separating lymph node stations by the surgeon from the gastric cancer specimen improves the quality of nodal status evaluation
World Journal of Surgical Oncology - Tập 21 - Trang 1-7 - 2023
Aleksi Fernström, Arto Kokkola, Akseli Korpela, Pauli Puolakkainen, Johanna Louhimo
In gastric cancer (GC), the pN-stage is an important prognostic factor influencing treatment. Along with the depth of invasion of the tumor, the presence of nodal metastases is one of the most important prognostic factors guiding treatment strategies in gastric cancer. Examining a small number of lymph nodes may lead to understaging of the disease; hence, it is essential for the nodal status to be...... hiện toàn bộ
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