Wiley
0003-276X
1097-0185
Cơ quản chủ quản: N/A
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Các bài báo tiêu biểu
Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionatorAbstract A stereological method for obtaining estimates of the total number of neurons in five major subdivisions of the rat hippocampus is described. The new method, the optical fractionator, combines two recent developments in stereology: a three‐dimensional probe for counting neuronal nuclei, the optical disector, and a systematic uniform sampling scheme, the fra... ...
Tập 231 Số 4 - Trang 482-497 - 1991
Bone “mass” and the “mechanostat”: A proposalAbstract The observed fit of bone mass to a healthy animal's typical mechanical usage indicates some mechanism or mechanisms monitor that usage and control the three longitudinal growth, bone modeling, and BMU‐based remodeling activities that directly determine bone mass. That mechanism could be named a mechanostat. Accumulated evidence suggests it includes the bone... ...
Tập 219 Số 1 - Trang 1-9 - 1987
Ruthenium red and violet. I. Chemistry, purification, methods of use for electron microscopy and mechanism of actionAbstract The properties of the inorganic dye ruthenium red are presented with emphasis upon its use for electron microscopy of cells and tissues. Although commercial ruthenium red often can be used directly, it always contains various impurities and by‐products. One of these, termed ruthenium violet, can be isolated and is useful by itself. Absorption spectra of the... ...
Tập 171 Số 3 - Trang 347-368 - 1971
Satellite cells as the source of nuclei in muscles of growing ratsAbstract The source of the new nuclei appearing during the growth of muscle fibers was examined in the tibialis anterior muscle of young Sherman rats (14–17 days of age) using radioautography at various intervals after a single injection of a small, non‐toxic dose of 3 H‐thymidine (2 μCi/g body weight). Two techniques were employed: (1) labeled n... ...
Tập 170 Số 4 - Trang 421-435 - 1971
The identification, origin, and migration of the primordial germ cells in the mouse embryo
Tập 118 Số 2 - Trang 135-146 - 1954
Degeneration of germ cells in normal, hypophysectomized and hormone treated hypophysectomized ratsAbstract In normal adult rats some germ cells degenerate at several vulnerable steps of spermatogenesis. These are the type A spermatogonia, midpachytene spermatocytes, primary and secondary spermatocytes which degenerate during their respective maturation divisions and step 7 and 19 spermatids. In the present study, these degenerating cells were examined under the ... ...
Tập 187 Số 3 - Trang 347-365 - 1977
The human cadaver in the age of biomedical informaticsAbstract Major national and international critiques of the medical curriculum in the 1980s noted the following significant flaws: (1) over‐reliance on learning by rote memory, (2) insufficient exercise in analysis and synthesis/conceptualization, and (3) failure to connect the basic and clinical aspects of training. It was argued that the invention of computers and ... ...
Tập 269 Số 1 - Trang 20-32 - 2002
Electron microscopy after rapid freezing on a metal surface and substitution fixationAbstract A method for rapid freezing is described in which use is made of the good heat conducting properties of silver. The freezing was accomplished by bringing the tissue in contact with a polished silver surface at the temperature of liquid nitrogen either at atmospheric or reduced pressure. Helium gas flowing over this surface prevented the condensation of wate... ...
Tập 149 Số 3 - Trang 381-385 - 1964