Wiley
0196-3635
1939-4640
Cơ quản chủ quản: N/A
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Các bài báo tiêu biểu
Spontaneous Lipid Peroxidation and Production of Hydrogen Peroxide and Superoxide in Human Spermatozoa Superoxide Dismutase as Major Enzyme Protectant Against Oxygen ToxicitySpontaneous lipid peroxidation in washed human spermatozoa was induced by aerobic incubation at 32 C and measured by malonaldehyde production; loss of motility during the incubation was determined simultaneously. Malonaldehyde production at the point of complete loss of motility, defined as the lipoperoxidative lethal end‐point (LLE), was 0.10 ± 0.03 nmol/108 cells (X̄... ...
Tập 8 Số 5 - Trang 338-348 - 1987
Significance of Reactive Oxygen Species and Antioxidants in Defining the Efficacy of Sperm Preparation TechniquesThe mechanisms responsible for mediating the influence of sperm preparation protocols on human sperm function have been investigated. Techniques that involved the separation of motile spermatozoa prior to centrifugation were found to yield sperm suspensions of highest quality. If the spermatozoa were centrifuged prior to isolation of the motile cells, sperm function was impaired. The detri... ...
Tập 9 Số 6 - Trang 367-376 - 1988
Oxidative Stress: A Common Factor in Testicular DysfunctionABSTRACT: Oxidative stress results from the production of oxygen radicals in excess of the antioxidant capacity of the stressed tissue. Many conditions or events associated with male infertility are inducers of oxidative stress. X‐irradiation, for example, or exposure to environmental toxicants and the physical conditions of varicocele and cryptorchidism have been dem...
Tập 29 Số 5 - Trang 488-498 - 2008
Comparison of Chromatin Assays for DNA Fragmentation Evaluation in Human SpermABSTRACT: Sperm chromatin integrity is vital for successful pregnancy and transmission of genetic material to the offspring. We evaluated chromatin integrity in sperm from 60 infertile men and 7 fertile donors comparing the sperm chromatin structure assay (SCSA), TdT‐mediated‐dUTP nick end labeling (TUNEL), the sperm chromatin dispersion (SCD) test, and acridine ora...
Tập 27 Số 1 - Trang 53-59 - 2006
Semen Cryopreservation in Domestic Animals: A Damaging and Capacitating Phenomenon Minireview
Tập 21 Số 1 - Trang 1-7 - 2000
Transgenerational Effect of the Endocrine Disruptor Vinclozolin on Male SpermatogenesisABSTRACT: The current study was designed to examine the actions of a model endocrine disruptor on embryonic testis development and male fertility. Pregnant rats (F0) that received a transient embryonic exposure to an environmental endocrine disruptor, vinclozolin, had male offspring (F1) with reduced spermatogenic capacity. The reduced spermatogenetic capacity obser...
Tập 27 Số 6 - Trang 868-879 - 2006
Managing the Risks of Prostate Disease During Testosterone Replacement Therapy in Older Men: Recommendations for a Standardized Monitoring Plan
Tập 24 Số 3 - Trang 299-311 - 2003
Urinary Metabolites of Di(2‐ethylhexyl) Phthalate Are Associated With Decreased Steroid Hormone Levels in Adult MenABSTRACT: Experimental animal studies have demonstrated that exposure to some phthalates may be associated with altered endocrine function and adverse effects on male reproductive development and function, but human studies are limited. In the present study, urine and serum samples were collected from 425 men recruited through a US infertility clinic. Urinary concen...
Tập 30 Số 3 - Trang 287-297 - 2009
The Sperm Chromatin Structure Assay Relationship with Alternate Tests of Semen Quality and Heterospermic Performance of BullsData obtained by the sperm chromatin structure assay (SCSA) on spermatozoa from nine bulls were correlated with fertility, measured by heterospermic performance (–0.94, P < 0.01) and by alternate tests of sperm quality, including motility, acrosome integrity, Sephadex filtration and morphology of spermatozoa (all significant at P <... ...
Tập 9 Số 2 - Trang 109-115 - 1988
Normal and Abnormal Development of the Male Urogenital TractABSTRACT: Androgen‐dependent male urogenital development occurs via mesenchymal‐epithelial interactions in which mesenchyme induces epithelial morphogenesis, regulates epithelial proliferation, and evokes expression of tissue‐specific secretory proteins. Mesenchymal‐epithelial interactions continue to be important into adulthood. For example, mesenchyme of the uroge...
Tập 13 Số 6 - Trang 465-475 - 1992