Wiley
SCOPUS (1980-2012)
0196-3635
1939-4640
Cơ quản chủ quản: N/A
Các bài báo tiêu biểu
Spontaneous Lipid Peroxidation and Production of Hydrogen Peroxide and Superoxide in Human Spermatozoa Superoxide Dismutase as Major Enzyme Protectant Against Oxygen Toxicity
Tập 8 Số 5 - Trang 338-348 - 1987
Spontaneous lipid peroxidation in washed human spermatozoa was induced by
aerobic incubation at 32 C and measured by malonaldehyde production; loss of
motility during the incubation was determined simultaneously. Malonaldehyde
production at the point of complete loss of motility, defined as the
lipoperoxidative lethal end‐point (LLE), was 0.10 ± 0.03 nmol/108 cells (X̄ ±
SD, n = 40), and was indep...
Significance of Reactive Oxygen Species and Antioxidants in Defining the Efficacy of Sperm Preparation Techniques
Tập 9 Số 6 - Trang 367-376 - 1988
The mechanisms responsible for mediating the influence of sperm preparation
protocols on human sperm function have been investigated. Techniques that
involved the separation of motile spermatozoa prior to centrifugation were found
to yield sperm suspensions of highest quality. If the spermatozoa were
centrifuged prior to isolation of the motile cells, sperm function was impaired.
The detrimental e...
Oxidative Stress: A Common Factor in Testicular Dysfunction
Tập 29 Số 5 - Trang 488-498 - 2008
ABSTRACT:Oxidative stress results from the production of oxygen radicals in
excess of the antioxidant capacity of the stressed tissue. Many conditions or
events associated with male infertility are inducers of oxidative stress.
X‐irradiation, for example, or exposure to environmental toxicants and the
physical conditions of varicocele and cryptorchidism have been demonstrated to
increase testicula...
Comparison of Chromatin Assays for DNA Fragmentation Evaluation in Human Sperm
Tập 27 Số 1 - Trang 53-59 - 2006
ABSTRACT: Sperm chromatin integrity is vital for successful pregnancy and
transmission of genetic material to the offspring. We evaluated chromatin
integrity in sperm from 60 infertile men and 7 fertile donors comparing the
sperm chromatin structure assay (SCSA), TdT‐mediated‐dUTP nick end labeling
(TUNEL), the sperm chromatin dispersion (SCD) test, and acridine orange staining
technique (AOT). Th...
Semen Cryopreservation in Domestic Animals: A Damaging and Capacitating Phenomenon Minireview
Tập 21 Số 1 - Trang 1-7 - 2000
Transgenerational Effect of the Endocrine Disruptor Vinclozolin on Male Spermatogenesis
Tập 27 Số 6 - Trang 868-879 - 2006
ABSTRACT: The current study was designed to examine the actions of a model
endocrine disruptor on embryonic testis development and male fertility. Pregnant
rats (F0) that received a transient embryonic exposure to an environmental
endocrine disruptor, vinclozolin, had male offspring (F1) with reduced
spermatogenic capacity. The reduced spermatogenetic capacity observed in the F1
male offspring was...
Managing the Risks of Prostate Disease During Testosterone Replacement Therapy in Older Men: Recommendations for a Standardized Monitoring Plan
Tập 24 Số 3 - Trang 299-311 - 2003
Urinary Metabolites of Di(2‐ethylhexyl) Phthalate Are Associated With Decreased Steroid Hormone Levels in Adult Men
Tập 30 Số 3 - Trang 287-297 - 2009
ABSTRACT: Experimental animal studies have demonstrated that exposure to some
phthalates may be associated with altered endocrine function and adverse effects
on male reproductive development and function, but human studies are limited. In
the present study, urine and serum samples were collected from 425 men recruited
through a US infertility clinic. Urinary concentrations of mono(2‐ethylhexyl)
p...
The Sperm Chromatin Structure Assay Relationship with Alternate Tests of Semen Quality and Heterospermic Performance of Bulls
Tập 9 Số 2 - Trang 109-115 - 1988
Data obtained by the sperm chromatin structure assay (SCSA) on spermatozoa from
nine bulls were correlated with fertility, measured by heterospermic performance
(–0.94, P < 0.01) and by alternate tests of sperm quality, including motility,
acrosome integrity, Sephadex filtration and morphology of spermatozoa (all
significant at P < 0.05 to P < 0.01). The SCSA uses flow cytometry to determine
the s...
Normal and Abnormal Development of the Male Urogenital Tract
Tập 13 Số 6 - Trang 465-475 - 1992
ABSTRACT: Androgen‐dependent male urogenital development occurs via
mesenchymal‐epithelial interactions in which mesenchyme induces epithelial
morphogenesis, regulates epithelial proliferation, and evokes expression of
tissue‐specific secretory proteins. Mesenchymal‐epithelial interactions continue
to be important into adulthood. For example, mesenchyme of the urogenital sinus
(UGM) and seminal ve...