Wiley

Công bố khoa học tiêu biểu

* Dữ liệu chỉ mang tính chất tham khảo

Sắp xếp:  
Androgen‐Induced Prostate‐Specific Antigen Gene Expression Is Mediated via Dihydrotestosterone in LNCaP Cells
Wiley - Tập 24 Số 5 - Trang 681-687 - 2003
Yuan‐Shan Zhu, Li‐Qun Cai, Xueke You, Juan Cordero, Ying Huang, Julianne Imperato‐McGinley
ABSTRACT: Prostate cancer is a leading cause of cancer death in American males. Androgens play an essential role in prostate development, growth and pathogenesis of benign prostate hyperplasia, and prostate cancer. Although testosterone is the main androgen secreted from the testes, dihydrotestosterone (DHT), a more potent androgen converted from testosterone by 5α‐reductase isozymes, type 1 and 2... hiện toàn bộ
High Levels of Sperm DNA Denaturation as the Sole Semen Abnormality in a Patient After Chemotherapy for Testis Cancer
Wiley - Tập 25 Số 1 - Trang 23-24 - 2004
Leslie A. Deane, Sharon Sharir, Keith Jarvi, Armand Zini
ANDROLOGY LAB CORNER*: One Semen Sample or 2? Insights From a Study of Fertile Men
Wiley - Tập 28 Số 5 - Trang 638-643 - 2007
Abbie Stokes‐Riner, Sally W. Thurston, Charlene Brazil, David S. Guzick, Fan Liu, James W. Overstreet, Christina Wang, Amy E. Sparks, Richard S. Crow, Shanna H. Swan
Relationship of Spermatozoal Migration in Cervical Mucus to Bovine Fertility
Wiley - Tập 2 Số 2 - Trang 103-107 - 1981
Hans L. Kummerfeld, Steven P. Lorton, R.H. Foote
Frozen bovine semen from males of wellestablished, generally high fertility levels was thawed and used in three experiments for In vitro capillary tube migration through cervical mucus. Bovine cervical mucus from individual heifers or a group of heifers was evaluated in these assays. Correlations between spermatozoal migration and bull fertility were small and not significant. Significant differen... hiện toàn bộ
Quantification of Bovine Sperm Separation by a Swim‐up Method Relationship to Sperm Motility, Integrity of Acrosomes, Sperm Migration in Polyacrylamide Gel and Fertility
Wiley - Tập 8 Số 4 - Trang 259-266 - 1987
J.J. Parrish, R.H. Foote
The number of bovine spermatozoa separated in a swim‐up procedure was quantified using an electronic cell counter. In an initial test of the swim‐up procedure, non‐frozen sperm samples with different ratios of live to dead cells were prepared and tested for the number of spermatozoa counted by the swim‐up procedure. In ejaculates from six bulls, the number of spermatozoa swimming up was related to... hiện toàn bộ
Oxidative Stress: A Common Factor in Testicular Dysfunction
Wiley - Tập 29 Số 5 - Trang 488-498 - 2008
Terry T. Turner, Jeffrey J. Lysiak
ABSTRACT:Oxidative stress results from the production of oxygen radicals in excess of the antioxidant capacity of the stressed tissue. Many conditions or events associated with male infertility are inducers of oxidative stress. X‐irradiation, for example, or exposure to environmental toxicants and the physical conditions of varicocele and cryptorchidism have been demonstrated to increase testicula... hiện toàn bộ
The Action of Calcitonin on the TM4 Sertoli Cell Line and on Rat Sertoli Cell‐Enriched Cultures
Wiley - Tập 10 Số 4 - Trang 321-331 - 1989
Atif M. Nakhla, Jennie P. Mather, Olli A. Jänne, C. Wayne Bardin
The effects of synthetic salmon calcitonin on primary Sertoli cell‐enriched cultures and on an established cell line (TM4 cells, derived from immature mouse Sertoli cells) were studied. Synthetic salmon calcitonin stimulated the conversion of [3H]adenine to [3H]cyclic AMP in both cell systems. In addition, this peptide stimulated the secretion of rABP in primary Sertoli cellenriched cultures prepa... hiện toàn bộ
A Simple, Clinical Assay to Evaluate The Acrosin Activity of Human Spermatozoa
Wiley - Tập 10 Số 3 - Trang 221-231 - 1989
William P. Kennedy, J. M. Kaminski, H.H. van der Ven, Rajasingam S. Jeyendran, D Reid, Jane M. Blackwell, P. Bielfeld, Lourens J.D. Zaneveld
Acrosin, a sperm‐specific arosomal proteinase, has an essential role in the fertilization process. Low levels of acrosin appear to be associated with subfertility and infertility, and the acrosin activity of spermatozoa may potentially be a useful indicator of semen quality. The standard acrosin tests employed by research laboratories are too complicated and/or time consuming for clinical use; the... hiện toàn bộ
Hypoxia‐Inducible Factor‐1α Is Constitutively Expressed in Murine Leydig Cells and Regulates 3β‐Hydroxysteroid Dehydrogenase Type 1 Promoter Activity
Wiley - Tập 30 Số 2 - Trang 146-156 - 2009
Jeffrey J. Lysiak, Jennifer L. Kirby, Jacques Tremblay, Robin I. Woodson, Michael A. Reardon, Lisa A. Palmer, Terry T. Turner
ABSTRACT: Hypoxia‐inducible factor‐1α (HIF‐1α) is a transcription factor that plays an essential role in oxygen homeostasis. HIF‐1α is constitutively made in cells; however, it is ubiquitinated and degraded under normoxic conditions. Hypoxia prevents the ubiquitination of HIF‐1α, resulting in stabilization of the protein and activation of target genes. Because of its vascular arrangement and the h... hiện toàn bộ
The Actions of Calcitonin on the TM3 Leydig Cell Line and on Rat Leydig Cell‐Enriched Cultures
Wiley - Tập 10 Số 4 - Trang 311-320 - 1989
Atif M. Nakhla, C. Wayne Bardin, Yoram Salomon, Jennie P. Mather, Olli A. Jänne
Studies demonstrating calcitonin receptors on Leydig cells have suggested that these cells may be one of the many sites affected by this peptide. To investigate this possibility, the effect of synthetic salmon calcitonin on the TM3 Leydig cell line (derived from immature mouse Leydig cells) and on primary Leydig cell‐enriched preparations was examined. Synthetic salmon calcitonin stimulated the co... hiện toàn bộ
Tổng số: 43   
  • 1
  • 2
  • 3
  • 4
  • 5