Minireview: Gut Microbiota: The Neglected Endocrine Organ Tập 28 Số 8 - Trang 1221-1238 - 2014
Gerard Clarke, Roman M. Stilling, Paul J. Kennedy, Catherine Stanton, John F. Cryan, Timothy G. Dinan
The concept that the gut microbiota serves as a virtual endocrine organ arises from a number of important observations. Evidence for a direct role arises from its metabolic capacity to produce and regulate multiple compounds that reach the circulation and act to influence the function of distal organs and systems. For example, metabolism of carbohydrates results in the production of short-...... hiện toàn bộ
Endocrine-Disrupting Organotin Compounds Are Potent Inducers of Adipogenesis in Vertebrates Tập 20 Số 9 - Trang 2141-2155 - 2006
Felix Grün, Hajime Watanabe, Zahra Zamanian, Lauren S. Maeda, Kayo Arima, Ryan Cubacha, David M. Gardiner, Jun Kanno, Taisen Iguchi, Bruce Blumberg
AbstractDietary and xenobiotic compounds can disrupt endocrine signaling, particularly of steroid receptors and sexual differentiation. Evidence is also mounting that implicates environmental agents in the growing epidemic of obesity. Despite a long-standing interest in such compounds, their identity has remained elusive. Here we show that the persistent and ubiqui...... hiện toàn bộ