A Review of Progress in Clinical Photodynamic Therapy Tập 4 Số 3 - Trang 283-293 - 2005
Zheng Huang
Photodynamic therapy (PDT) has received increased attention since the regulatory
approvals have been granted to several photosensitizing drugs and light
applicators worldwide. Much progress has been seen in basic sciences and
clinical photodynamics in recent years. This review will focus on new
developments of clinical investigation and discuss the usefulness of various
forms of PDT techniques for... hiện toàn bộ
CyberKnife Radiotherapy for Localized Prostate Cancer: Rationale and Technical Feasibility Tập 2 Số 1 - Trang 25-29 - 2003
Christopher King, Jöerg Lehmann, John R. Adler, Jenny Hai
There is a clear dose response for localized prostate cancer radiotherapy and
there probably is a radiobiological rationale for hypo-fractionation. Combining
the two should maximize tumor control and increase the therapeutic ratio. This
study examines the rationale and technical feasibility of CyberKnife
radiotherapy (a robotic arm-driven linear accelerator) for localized prostate
cancer. Its abil... hiện toàn bộ
Stereotactic Body Radiotherapy: An Emerging Treatment Approach for Localized Prostate Cancer Tập 8 Số 5 - Trang 387-392 - 2009
Jay L. Friedland, Debra Freeman, Mary Ellen Masterson-McGary, David M. Spellberg
Here we report results from the first cohort of over 100 patients treated with
hypofractionated, stereotactic body radiotherapy (SBRT) for early stage prostate
cancer. Between February 2005 and December 2006, 112 patients with localized,
biopsy-proven adenocarcinoma of the prostate (clinical stage T1cN0M0 to T2cN0M0)
were treated in Naples, FL on a CyberKnife system (Accuray Incorporated,
Sunnyval... hiện toàn bộ
Image-Guided Stereotactic Body Radiation Therapy for Clinically Localized Prostate Cancer: Preliminary Clinical Results Tập 9 Số 5 - Trang 473-477 - 2010
Giampaolo Bolzicco, Maria Silvia Favretto, E. Scremin, C. Tambone, A. Tasca, Rosabianca Guglielmi
Stereotactic body radiotherapy (SBRT) is a new treatment modality for prostate
cancer. The current study evaluates CyberKnife® SBRT and reports toxicity and
early Prostate-Specific Antigen (PSA) kinetics. From June 2006 to August 2009,
45 low-and intermediate-risk prostate cancer patients received Cyberknife SBRT
of 35 Gy in five fractions with 95% minimum target coverage. Median follow-up
was 20-... hiện toàn bộ
The Diagnostic Efficacy and Biological Effects of microRNA-29b for Colon Cancer Tập 15 Số 6 - Trang 772-779 - 2016
Leping Li, Ying Guo, Yuezhi Chen, Jinshen Wang, Zhen Lei, Xiaobo Guo, Jinglei Liu, Changqing Jing
Background: Colorectal cancer is one of the most common cancers worldwide in
terms of both incidence and mortality. The associations of expressions of tissue
and plasma miR-29b were not detected in this study. Methods: There are 400
healthy age- and gender-matched controls enrolled in this study in a rate of
1:2. The receiver operating characteristic curve analysis was undertaken using
the express... hiện toàn bộ
Low Generation Polypropylenimine Dendrimer Graft β-cyclodextrin: An Efficient Vector for Gene Delivery System Tập 7 Số 2 - Trang 103-108 - 2008
Wei Zhang, Zhe Chen, Xiaoxiao Song, Jianmin Si, Guping Tang
The purpose of this study was to evaluate the characterization of a new cationic
vector. Low generation polypropylenimine (DAB-8) was conjugated to
β-cyclodextrin (β-CyD), and the chemical characters of the vector were
investigated and confirmed by 1 H NMR, FT-IR, TGA, TEM, particle size, and zeta
potential assay. The biological property was identified by MTT assay and gene
transfer efficiency was... hiện toàn bộ
MFAP2 Promotes the Proliferation of Cancer Cells and Is Associated With a Poor Prognosis in Hepatocellular Carcinoma Tập 19 - 2020
Xiang Zhu, Ye Cheng, Fan Wu, Haoyao Sun, Wubin Zheng, Wei Jiang, Junfeng Shi, Shijie Ma, Hongyong Cao
Backgrounds: Microfibril-associated protein 2 (MFAP2) is an extracellular matrix
protein that regulates the function of microfibrils by interacting with
fibrillin. MFAP2 has been reported to play an important role in metabolic
diseases and has been shown to be significantly overexpressed in head and neck
squamous cell carcinoma and Hepatocellular carcinoma (HCC). However, the
molecular function an... hiện toàn bộ
A Competing Endogenous RNA Network Reveals Novel lncRNA, miRNA and mRNA Biomarkers With Diagnostic and Prognostic Value for Early Breast Cancer Tập 19 - Trang 153303382098329 - 2020
Zhongbing Luo, Guie Lai, Tao Jiang, Chuanlin Cao, Tao Peng, Fengen Liu
Background: This study aims to reveal early breast cancer (BC) specific
competing endogenous RNA (ceRNA) network through the expression profiles of
microRNAs (miRNAs), long non-coding RNAs (lncRNAs) and mRNAs. Methods: Based on
The Cancer Genome Atlas (TCGA), we obtained the differentially expressed mRNAs,
miRNAs, and lncRNAs (DEmRNAs, DEmiRNAs and DElncRNAs) between early BC and
normal samples. T... hiện toàn bộ
Desloratadine, a Novel Antigrowth Reagent for Bladder Cancer Tập 19 - 2020
MA Jian-feng, Jin‐Chun Qi, Shoubin Li, Chaohua Zhang, Haijiang Wang, Lijun Shao, Xiaofei Yuan, Quan Sha
Desloratadine, a potent antagonist for human histamine H1 receptor, has been
revealed to exhibit antihistaminic activity and anti-inflammatory activity.
However, it is not yet known whether desloratadine has any effect on the
biological behaviors of tumor cells. In this study, we aimed to investigate the
effects of desloratadine on cell growth and invasion in bladder cancer EJ and
SW780 cells in v... hiện toàn bộ