Technology in Cancer Research and Treatment

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SKA3 Promotes Cell Growth in Breast Cancer by Inhibiting PLK-1 Protein Degradation
Technology in Cancer Research and Treatment - Tập 19 - Trang 153303382094748 - 2020
Liwei Ruan, Pengpeng Li, Langping Jin
Breast cancer (Bca) remains the most common form of malignancy affecting females in China, leading to significant reductions in the mental and physical health of those with this condition. While spindle and kinetochore associated complex subunit 3 (SKA3) is known to be linked with cervical cancer progression, whether it is similarly associated with Bca progression remains unknown. Using s...... hiện toàn bộ
A Review of Progress in Clinical Photodynamic Therapy
Technology in Cancer Research and Treatment - Tập 4 Số 3 - Trang 283-293 - 2005
Zheng Huang
Photodynamic therapy (PDT) has received increased attention since the regulatory approvals have been granted to several photosensitizing drugs and light applicators worldwide. Much progress has been seen in basic sciences and clinical photodynamics in recent years. This review will focus on new developments of clinical investigation and discuss the usefulness of various forms of PDT techn...... hiện toàn bộ
Image-Guided Stereotactic Body Radiation Therapy for Clinically Localized Prostate Cancer: Preliminary Clinical Results
Technology in Cancer Research and Treatment - Tập 9 Số 5 - Trang 473-477 - 2010
Giampaolo Bolzicco, Maria Silvia Favretto, E. Scremin, C. Tambone, A. Tasca, Rosabianca Guglielmi
Stereotactic body radiotherapy (SBRT) is a new treatment modality for prostate cancer. The current study evaluates CyberKnife® SBRT and reports toxicity and early Prostate-Specific Antigen (PSA) kinetics. From June 2006 to August 2009, 45 low-and intermediate-risk prostate cancer patients received Cyberknife SBRT of 35 Gy in five fractions with 95% minimum target coverage. Median follow-u...... hiện toàn bộ
Stereotactic Body Radiotherapy: An Emerging Treatment Approach for Localized Prostate Cancer
Technology in Cancer Research and Treatment - Tập 8 Số 5 - Trang 387-392 - 2009
Jay L. Friedland, Debra Freeman, Mary Ellen Masterson-McGary, David M. Spellberg
Here we report results from the first cohort of over 100 patients treated with hypofractionated, stereotactic body radiotherapy (SBRT) for early stage prostate cancer. Between February 2005 and December 2006, 112 patients with localized, biopsy-proven adenocarcinoma of the prostate (clinical stage T1cN0M0 to T2cN0M0) were treated in Naples, FL on a CyberKnife system (Accuray Incorporated,...... hiện toàn bộ
CyberKnife Radiotherapy for Localized Prostate Cancer: Rationale and Technical Feasibility
Technology in Cancer Research and Treatment - Tập 2 Số 1 - Trang 25-29 - 2003
Christopher King, Jöerg Lehmann, John R. Adler, Jenny Hai
There is a clear dose response for localized prostate cancer radiotherapy and there probably is a radiobiological rationale for hypo-fractionation. Combining the two should maximize tumor control and increase the therapeutic ratio. This study examines the rationale and technical feasibility of CyberKnife radiotherapy (a robotic arm-driven linear accelerator) for localized prostate cancer....... hiện toàn bộ
Targeting Accuracy in Real-time Tumor Tracking via External Surrogates: A Comparative Study
Technology in Cancer Research and Treatment - Tập 9 Số 6 - Trang 551-561 - 2010
Ahmad Esmaili Torshabi, Andrea Pella, Marco Riboldi, G. Baroni
The use of external surrogates to predict tumor motion in real-time for extra-cranial sites requires the use of accurate correlation models. This is extremely challenging when motion prediction is to be performed over several breathing cycles, as occurs for realtime tumor tracking with Cyberknife® Synchrony®. In this work we compare three different approaches to infer tumor motion based o...... hiện toàn bộ
Low Generation Polypropylenimine Dendrimer Graft β-cyclodextrin: An Efficient Vector for Gene Delivery System
Technology in Cancer Research and Treatment - Tập 7 Số 2 - Trang 103-108 - 2008
Wei Zhang, Zhe Chen, Xiaoxiao Song, Jianmin Si, Guping Tang
The purpose of this study was to evaluate the characterization of a new cationic vector. Low generation polypropylenimine (DAB-8) was conjugated to β-cyclodextrin (β-CyD), and the chemical characters of the vector were investigated and confirmed by 1 H NMR, FT-IR, TGA, TEM, particle size, and zeta potential assay. The biological property was identified by MTT assay an...... hiện toàn bộ
The Diagnostic Efficacy and Biological Effects of microRNA-29b for Colon Cancer
Technology in Cancer Research and Treatment - Tập 15 Số 6 - Trang 772-779 - 2016
Leping Li, Ying Guo, Yuezhi Chen, Jinshen Wang, Zhen Lei, Xiaobo Guo, Jinglei Liu, Changqing Jing
Background: Colorectal cancer is one of the most common cancers worldwide in terms of both incidence and mortality. The associations of expressions of tissue and plasma miR-29b were not detected in this study. Methods: There are 400 healthy age- and gender-matched controls enrolled in this stu...... hiện toàn bộ
The Assessment of Clinical Usage and Prognostic Value of YKL-40 Serum Levels in Patients With Rectal Cancer Without Distant Metastasis
Technology in Cancer Research and Treatment - Tập 17 - 2018
Małgorzata Fuksiewicz, Beata Kotowicz, Andrzej Rutkowski, Joanna Achinger-Kawecka, Michał Wągrodzki, M Kowalska
Background: Colorectal cancer is one of the most common and significant malignancies in the world. YKL-40 (chitinase-3-like protein 1) is involved in cell proliferation, migration, inflammation, and tissue remodeling; and serum levels of YKL-40 are associated with patient outcome in various cancers. The aim of this study was to assess the potential clinic...... hiện toàn bộ
Factors Associated with Pulmonary Function Changes in Patients Undergoing Microwave Ablation for Pulmonary Ground-Glass Nodules
Technology in Cancer Research and Treatment - Tập 21 - 2022
Weida Wu, Jianyang Peng, Hongbin Gao, Yuanzhen Lin, Qunying Lin, Zhicheng Weng
Purpose: Microwave ablation has become an alternative treatment for pulmonary ground-glass nodules (GGN) and is widely accepted by clinicians. However, its effect on lung function remains unknown. Therefore, this retrospective study aimed to explore pulmonary function changes and associated risk factors in patients undergoing computed tomography (CT)-guided microwave ablation (MWA) for tr...... hiện toàn bộ
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