Springer Science and Business Media LLC
SCIE-ISI SCOPUS (2011-2023)
2045-8118
Cơ quản chủ quản: BioMed Central Ltd. , BMC
Lĩnh vực:
Developmental NeuroscienceCellular and Molecular NeuroscienceMedicine (miscellaneous)Neurology
Các bài báo tiêu biểu
The hCMEC/D3 cell line as a model of the human blood brain barrierAbstract
Since the first attempts in the 1970s to isolate cerebral microvessel endothelial cells (CECs) in order to model the blood–brain barrier (BBB) in vitro , the need for a human BBB model that closely mimics the in vivo phenotype and is reproducible and easy to grow, has been widely recognized by ... ...
Tập 10 Số 1 - 2013
A blood–brain barrier overview on structure, function, impairment, and biomarkers of integrityAbstract The blood–brain barrier is playing a critical role in controlling the influx and efflux of biological substances essential for the brain’s metabolic activity as well as neuronal function. Thus, the functional and structural integrity of the BBB is pivotal to maintain the homeostasis of the brain microenvironment. The different cells and structures contribut... ...
- 2020
The pulsating brain: A review of experimental and clinical studies of intracranial pulsatility
Tập 8 Số 1 - 2011
Nonsurgical therapy for hydrocephalus: a comprehensive and critical review
Tập 13 - Trang 1-20 - 2016
Pharmacological interventions have been tested experimentally and clinically to prevent hydrocephalus and avoid the need for shunting beginning in the 1950s. Clinical trials of varied quality have not demonstrated lasting and convincing protective effects through manipulation of cerebrospinal fluid production, diuresis, blood clot fibrinolysis, or manipulation of fibrosis in the subarachnoid compa......
Modeling the blood–brain barrier using stem cell sourcesAbstract
The blood–brain barrier (BBB) is a selective endothelial interface that controls trafficking between the bloodstream and brain interstitial space. During development, the BBB arises as a result of complex multicellular interactions between immature endothelial cells and neural progenitors, neurons, radial glia, and pericytes. As the brain develop... ...
Tập 10 Số 1 - 2013
Role of iPSC-derived pericytes on barrier function of iPSC-derived brain microvascular endothelial cells in 2D and 3D
Tập 16 Số 1 - 2019
Developmental changes in the transcriptome of the rat choroid plexus in relation to neuroprotectionAbstract
Background
The choroid plexuses are the interface between the blood and the cerebrospinal fluid (CSF) contained within the ventricular spaces of the central nervous system. The tight junctions linking adjacent cells of the choroidal epithelium create a physical barrier to paracellular mo... ...
- 2013