Discovery and SAR exploration of N-aryl-N-(3-aryl-1,2,4-oxadiazol-5-yl)amines as potential therapeutic agents for prostate cancerSpringer Science and Business Media LLC - Tập 4 - Trang 1-5 - 2010
Mikhail Krasavin, Konstantin A Rufanov, Andrey V Sosnov, Ruben Karapetian, Elena Godovykh, Olga Soldatkina, Yan Lavrovsky, Andrei A Gakh
A new chemical series of antiproliferative compounds was identified via high-throughput screening on DU-145 human prostate carcinoma cell line (hit compound potency - 5.7 μM). Exploration of the two peripheral diversity vectors of the hit molecule in a hit-targeted library and testing of the resulting compounds led to SAR generalizations and identification of the 'best' pharmacophoric moieties. Th...... hiện toàn bộ
GC-MS studies of the chemical composition of two inedible mushrooms of the genus AgaricusSpringer Science and Business Media LLC - Tập 1 - Trang 1-5 - 2007
Assya Petrova, Kalina Alipieva, Emanuela Kostadinova, Daniela Antonova, Maria Lacheva, Melania Gjosheva, Simeon Popov, Vassya Bankova
Mushrooms in the genus Agaricus have worldwide distribution and include the economically important species A. bisporus. Some Agaricus species are inedible, including A. placomyces and A. pseudopratensis, which are similar in appearance to certain edible species, yet are known to possess unpleasant odours and induce gastrointestinal problems if consumed. We have studied the chemical composition of ...... hiện toàn bộ
Microwave synthesis and thermal properties of polyacrylate derivatives containing itaconic anhydride moietiesSpringer Science and Business Media LLC - Tập 6 - Trang 1-11 - 2012
Sameh M Osman, Mohamed H El-Newehy, Salem S Al-Deyab, Ayman El-Faham
Microwave irradiation as an alternative heat source is now a well-known method in synthetic chemistry. Microwave heating has emerged as a powerful technique to promote a variety of chemical reactions, offering reduced pollution, low cost and offer high yields together with simplicity in processing and handling. On the other hand, copolymers containing both hydrophilic and hydrophobic segments are ...... hiện toàn bộ
Preparation and application of melamine cross-linked poly ammonium as shale inhibitorSpringer Science and Business Media LLC - - 2018
Li Zhang, Tiehu Li, Huang Lei, Zhengqin Ye, Zhongbin Ye, Yan Xiao, Lili Li, Qiang Deng, Gang Chen, Jie Zhang, Zhifang Zhang
Bioaccumulative and conchological assessment of heavy metal transfer in a soil-plant-snail food chainSpringer Science and Business Media LLC - - 2012
Dragoş Nica, Marian Bura, I. Gergen, Monica Hărmănescu, Despina-Maria Bordean
Abstract
Background
Copper (Cu), zinc (Zn), cadmium (Cd), and lead (Pb) can pose serious threats to environmental health because they tend to bioaccumulate in terrestrial ecosystems. We investigated under field conditions the transfer of these heavy metals in a soil-plant-snail food chain in Bana...... hiện toàn bộ