Automethylation of protein arginine methyltransferase 6 (PRMT6) regulates its stability and its anti-HIV-1 activitySpringer Science and Business Media LLC - Tập 10 - Trang 1-10 - 2013
Diane N Singhroy, Thibault Mesplède, Arielle Sabbah, Peter K Quashie, Jean-Pierre Falgueyret, Mark A Wainberg
Protein arginine methyltransferase 6 (PRMT6) is a nuclear enzyme that methylates arginine residues on histones and transcription factors. In addition, PRMT6 inhibits HIV-1 replication in cell culture by directly methylating and interfering with the functions of several HIV-1 proteins, i.e. Tat, Rev and nucleocapsid (NC). PRMT6 also displays automethylation capacity but the role of this post-transl...... hiện toàn bộ
MicroRNAs expression in CD4 T cells from HTLV-1 individualsSpringer Science and Business Media LLC - Tập 11 - Trang 1-1 - 2014
Kátia Kaori Otaguiri, Mariana Tomazini Pinto, Evandra Strazza Rodrigues, Virgínia Mara de Deus Wagatsuma, Maurício Cristiano Rocha Júnior, Osvaldo Massaiti Takayanagui, Dimas Tadeu Covas, Simone Kashima
OA04-03. Characterization of cell-mediated immune responses generated by recombinant modified vaccinia Ankara (rMVA)-HIV-1 in a phase I vaccine trialSpringer Science and Business Media LLC - Tập 6 - Trang 1-1 - 2009
JR Currier, M De Souza, S Ratto-Kim, R Paris, V Nguay, J Cox, P Earl, B Moss, S Sriplienchan, P Thongcharoen, J Kim, M Robb, N Michael, M Marovich
Promising results of an anti-CCR4 antibody, KW-0761, for relapsed Adult T-Cell Leukemia-Lymphoma (ATL)Springer Science and Business Media LLC - Tập 8 - Trang 1-1 - 2011
Atae Utsunomiya, Kensei Tobinai, Kazuhito Yamamoto, Takashi Ishida, Naokuni Uike, Kunihiro Tsukasaki, Kimiharu Uozumi, Masao Tomonaga, Ryuzo Ueda
2-thio-6-azauridine inhibits Vpu mediated BST-2 degradationSpringer Science and Business Media LLC - Tập 13 - Trang 1-14 - 2016
Quan Zhang, Zeyun Mi, Yuming Huang, Ling Ma, Jiwei Ding, Jing Wang, Yongxin Zhang, Yang chen, Jinming Zhou, Fei Guo, Xiaoyu Li, Shan Cen
BST-2 is an interferon-induced host restriction factor that inhibits the release of diverse mammalian enveloped viruses from infected cells by physically trapping the newly formed virions onto the host cell surface. Human Immunodeficiency Virus-1 (HIV-1) encodes an accessory protein Vpu that antagonizes BST-2 by down-regulating BST-2 from the cell surface. Using a cell-based ELISA screening syste...... hiện toàn bộ