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Full-length HIV-1 immunogens induce greater T lymphocyte responses to conserved epitopes than conserved-region-only HIV-1 immunogens in monkeys
Springer Science and Business Media LLC - - 2012
Katherine Stephenson, Adam J. SanMiguel, NL Simmons, Kiersten S. Smith, James Szinger, BT Korber, DH Barouch
Partial inhibition of HIV replication by type-I interferons: impact of cell-to-cell viral transfer
Springer Science and Business Media LLC - Tập 6 - Trang 1-1 - 2009
Daniela Vendrame, Marion Sourisseau, Virginie Perrin, Olivier Schwartz, Fabrizio Mammano
Partial rescue of V1V2 mutant infectivity by HIV-1 cell-cell transmission supports the domain’s exceptional capacity for sequence variation
Springer Science and Business Media LLC - Tập 11 - Trang 1-22 - 2014
Oliver F Brandenberg, Peter Rusert, Carsten Magnus, Jacqueline Weber, Jürg Böni, Huldrych F Günthard, Roland R Regoes, Alexandra Trkola
Variable loops 1 and 2 (V1V2) of the HIV-1 envelope glycoprotein gp120 perform two key functions: ensuring envelope trimer entry competence and shielding against neutralizing antibodies. While preserving entry functionality would suggest a high need for V1V2 sequence optimization and conservation, shielding efficacy is known to depend on a high flexibility of V1V2 giving rise to its substantial se...... hiện toàn bộ
Determinants of FIV and HIV Vif sensitivity of feline APOBEC3 restriction factors
Springer Science and Business Media LLC - Tập 13 - Trang 1-23 - 2016
Zeli Zhang, Qinyong Gu, Ananda Ayyappan Jaguva Vasudevan, Anika Hain, Björn-Philipp Kloke, Sascha Hasheminasab, Daniel Mulnaes, Kei Sato, Klaus Cichutek, Dieter Häussinger, Ignacio G. Bravo, Sander H. J. Smits, Holger Gohlke, Carsten Münk
Feline immunodeficiency virus (FIV) is a global pathogen of Felidae species and a model system for Human immunodeficiency virus (HIV)-induced AIDS. In felids such as the domestic cat (Felis catus), APOBEC3 (A3) genes encode for single-domain A3Z2s, A3Z3 and double-domain A3Z2Z3 anti-viral cytidine deaminases. The feline A3Z2Z3 is expressed following read-through transcription and alternative splic...... hiện toàn bộ
Immune activation, viral replication and mucosal depletion
Springer Science and Business Media LLC - Tập 3 - Trang 1-1 - 2006
Zvi Grossman
Willingness to participate in vaccine trials among MSM in São Paulo, Brazil
Springer Science and Business Media LLC - Tập 9 - Trang 1-1 - 2012
G Calazans, A Kalichman, M Veras, R Gamboa, M Ribeiro
Vicriviroc (SCH 417690) Distribution from the Gut to Gut-Associated Lymphoid Tissues (GALT) and to Peripheral Lymphoid Tissues Following an Oral Dose
Springer Science and Business Media LLC - Tập 2 - Trang 1-1 - 2005
Ian Knemeyer, Lee Crossman, Mark Wirth
Recombinant DNA/MVA/ChAdV-63-elicited T cells specific for conserved regions of the HIV-1 proteome recognize HIV-1 infected cells and suppress HIV-1
Springer Science and Business Media LLC - Tập 9 - Trang 1-1 - 2012
T Ahmed, N Borthwick, H Yang, G Hancock, L Yorke, U Ebrahimsa, A Rose, A Black, E Hayton, A McMichael, L Dorrell, T Hanke
More than meets the I: the diverse antiviral and cellular functions of interferon-induced transmembrane proteins
Springer Science and Business Media LLC - Tập 14 - Trang 1-11 - 2017
Guoli Shi, Olivier Schwartz, Alex A. Compton
The first responders of human antiviral immunity are components of the intrinsic immune response that reside within each and every one of our cells. This cell-autonomous arsenal consists of nucleic acid sensors and antiviral effectors strategically placed by evolution to detect and restrict invading viruses. While some factors are present at baseline to allow for constant surveillance of the cell...... hiện toàn bộ
Preferential expression of human endogenous retrovirus K (HERV-K/HML-2) type 1 in tumor cells
Springer Science and Business Media LLC - Tập 8 - Trang 1-1 - 2011
Camila M Romano, Fernando L de Melo, Paolo M de A Zanotto
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