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Automethylation of protein arginine methyltransferase 6 (PRMT6) regulates its stability and its anti-HIV-1 activity
Springer Science and Business Media LLC - Tập 10 - Trang 1-10 - 2013
Diane N Singhroy, Thibault Mesplède, Arielle Sabbah, Peter K Quashie, Jean-Pierre Falgueyret, Mark A Wainberg
Protein arginine methyltransferase 6 (PRMT6) is a nuclear enzyme that methylates arginine residues on histones and transcription factors. In addition, PRMT6 inhibits HIV-1 replication in cell culture by directly methylating and interfering with the functions of several HIV-1 proteins, i.e. Tat, Rev and nucleocapsid (NC). PRMT6 also displays automethylation capacity but the role of this post-transl...... hiện toàn bộ
MicroRNAs expression in CD4 T cells from HTLV-1 individuals
Springer Science and Business Media LLC - Tập 11 - Trang 1-1 - 2014
Kátia Kaori Otaguiri, Mariana Tomazini Pinto, Evandra Strazza Rodrigues, Virgínia Mara de Deus Wagatsuma, Maurício Cristiano Rocha Júnior, Osvaldo Massaiti Takayanagui, Dimas Tadeu Covas, Simone Kashima
P16-51. Functional characterization of novel SIV epitope specific T cells
Springer Science and Business Media LLC - Tập 6 - Trang 1-1 - 2009
N Winstone, K Mullen, A Wilson, A McDermott
OA04-03. Characterization of cell-mediated immune responses generated by recombinant modified vaccinia Ankara (rMVA)-HIV-1 in a phase I vaccine trial
Springer Science and Business Media LLC - Tập 6 - Trang 1-1 - 2009
JR Currier, M De Souza, S Ratto-Kim, R Paris, V Nguay, J Cox, P Earl, B Moss, S Sriplienchan, P Thongcharoen, J Kim, M Robb, N Michael, M Marovich
Probing Cell-to-cell Transfer of Human T-cell Leukaemia Virus Type-1 Using Novel Inhibitors of Viral Entry
Springer Science and Business Media LLC - - 2005
Chien‐Wen Kuo, Antonis Mirsaliotis, Kulpash Nurkiyanova, David W. Brighty
Promising results of an anti-CCR4 antibody, KW-0761, for relapsed Adult T-Cell Leukemia-Lymphoma (ATL)
Springer Science and Business Media LLC - Tập 8 - Trang 1-1 - 2011
Atae Utsunomiya, Kensei Tobinai, Kazuhito Yamamoto, Takashi Ishida, Naokuni Uike, Kunihiro Tsukasaki, Kimiharu Uozumi, Masao Tomonaga, Ryuzo Ueda
Co-circulation of two envelope variants for both gorilla and chimpanzee Simian Foamy Virus strains among humans and apes living in Central Africa
Springer Science and Business Media LLC - Tập 12 - Trang 1-1 - 2015
Léa Richard, Rejane Rua, Edouard Betsem, Augustin Mouinga-Ondémé, Mirdad Kazanji, Eric Leroy, Florence Buseyne, Philippe V Afonso, Antoine Gessain
Pre-exposure prophylaxis (PrEP) in an era of stalled HIV prevention: Can it change the game?
Springer Science and Business Media LLC - Tập 15 Số 1 - 2018
Robyn Eakle, François Venter, Helen Rees
Site directed mutagenesis studies on HIV-1 reverse transcriptase (RT) shed light on the mechanism of action of a new Ribonuclease H/ DNA polymerase RT dual inhibitor
Springer Science and Business Media LLC - Tập 10 - Trang 1-2 - 2013
Angela Corona, Rita Meleddu, Francesca Esposito, Simona Distinto, Giulia Bianco, Elias Maccioni, Stuart SF Le Grice, Enzo Tramontano
2-thio-6-azauridine inhibits Vpu mediated BST-2 degradation
Springer Science and Business Media LLC - Tập 13 - Trang 1-14 - 2016
Quan Zhang, Zeyun Mi, Yuming Huang, Ling Ma, Jiwei Ding, Jing Wang, Yongxin Zhang, Yang chen, Jinming Zhou, Fei Guo, Xiaoyu Li, Shan Cen
BST-2 is an interferon-induced host restriction factor that inhibits the release of diverse mammalian enveloped viruses from infected cells by physically trapping the newly formed virions onto the host cell surface. Human Immunodeficiency Virus-1 (HIV-1) encodes an accessory protein Vpu that antagonizes BST-2 by down-regulating BST-2 from the cell surface. Using a cell-based ELISA screening syste...... hiện toàn bộ
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