Thiazolopyrimidine derivatives as novel class of small molecule tyrosinase inhibitorSpringer Science and Business Media LLC - Tập 17 - Trang 1-11 - 2023
Nastaran Ghasemi, Shahram Moradi, Aida Iraji, Mohammad Mahdavi
Tyrosinase, the rate-limiting enzyme of melanogenesis, plays a crucial role in
hyperpigmentation. As a result, in this study, a novel class of
thiazolopyrimidine derivatives was developed and synthesized as tyrosinase
inhibitor. The structure of derivatives was characterized using various
spectroscopy techniques, including FTIR, Mass, 1H-NMR, and 13C-NMR. Next, the
inhibitory activities of all der... hiện toàn bộ
Novel 8-Methoxycoumarin-3-Carboxamides with potent anticancer activity against liver cancer via targeting caspase-3/7 and β-tubulin polymerizationSpringer Science and Business Media LLC - Tập 17 - Trang 1-22 - 2023
Ahmad Alzamami, Eman M. Radwan, Eman Abo-Elabass, Mohammed El Behery, Hussah Abdullah Alshwyeh, Ebtesam Al-Olayan, Abdulmalik S. Altamimi, Nashwah G. M. Attallah, Najla Altwaijry, Mariusz Jaremko, Essa M. Saied
In the present study, we explored the potential of coumarin-based compounds,
known for their potent anticancer properties, by designing and synthesizing a
novel category of 8-methoxycoumarin-3-carboxamides. Our aim was to investigate
their antiproliferative activity against liver cancer cells. Toward this, we
developed a versatile synthetic approach to produce a series of
8-methoxycoumarin-3-carbo... hiện toàn bộ
Species diversity of different insect families trapped under beer-based volatile fermentationSpringer Science and Business Media LLC - Tập 14 - Trang 1-12 - 2020
Mazher Farid Iqbal, Yu-Long Feng
Insect species composition is an important phenomenon playing a significant role
in the ecosystem. Chemical control of insects and pests releases toxic materials
to the environment. These chemicals are dangerous to human populations. In this
situation, there is a dire need to develop strategies to overcome the haphazard
use of chemicals. The present investigations were carried out to explore the
d... hiện toàn bộ
The effect of microwave stabilization on the properties of whole wheat flour and its further interpretation by molecular dockingSpringer Science and Business Media LLC - Tập 15 - Trang 1-9 - 2021
Chenling Qu, Qiankui Yang, Lina Ding, Xueke Wang, Shengqiang Liu, Min Wei
In order to stabilize the whole wheat flour and extend its shelf life, microwave
was employed to heat the wheat bran to inactivate the lipase in this paper. The
effects of microwave heating of wheat bran on the lipase activities, gluten
properties, dough properties and storage stability of the stabilized whole wheat
flour, and the quality of steamed bread made of stabilized whole wheat flour
were ... hiện toàn bộ
Synthesis, characterization, and antibacterial activity studies of two Co(II) complexes with 2-[(E)-(3-acetyl-4-hydroxyphenyl)diazenyl]-4-(2-hydroxyphenyl)thiophene-3-carboxylic acid as a ligandSpringer Science and Business Media LLC - Tập 18 Số 1
Emmanuel Sopbué Fondjo, Sorelle Songmi Feuze, Jean-De-Dieu Tamokou, Apollinaire Tsopmo, Giscard Doungmo, Peter F. W. Simon, Donald Léonel Feugap Tsamo, Bruno Lenta Ndjakou, Kuiate Jules-Roger
AbstractTwo new Cobalt(II) complexes 12 and 13 have been synthesized from
2-[(E)-(3-acetyl-4-hydroxyphenyl)diazenyl]-4-(2-hydroxyphenyl)thiophene-3-carboxylic
acid (11) as a novel ligand. These three new compounds were characterized on the
basis of their powder X-Ray Diffraction, UV–Vis, IR, NMR, elemental analysis and
MS spectral data. DFT/B3LYP mode of calculations were carried out to determine
... hiện toàn bộ
Green and simple production of graphite intercalation compound used sodium bicarbonate as intercalation agentSpringer Science and Business Media LLC - Tập 16 - Trang 1-10 - 2022
Xin Wang, Guogang Wang, Long Zhang
In view of the technical difficulties in the preparation of graphite
intercalation compound (GIC) such as complex processes, the need to use strong
acid reagents, and the product containing corrosive elements. A novel, efficient
and simple method used sodium bicarbonate as intercalation agent was developed,
which combined with mechanical force and chemical method for the green
production of GIC. T... hiện toàn bộ
Compost preparation, chemical analyses and users’ perception in the utilization of water hyacinth, EthiopiaSpringer Science and Business Media LLC - Tập 16 - Trang 1-10 - 2022
Dessie Tibebe, Kehali Jembere, Addisu Kidie, Marelign Adugna, Teferi Alem, Gizachew Teshome
Lake Tana is the largest freshwater body in Ethiopia. Currently, the lake has
been facing alarming environmental degradation and loss of biodiversity due to
the invasion of water hyacinth. Although the weed is invasive, it can be
converted into various benefits. Hence, this study was conducted in North
Eastern Lake Tana, Sheha Gomengie Kebele. The main objective is compost
preparation in terms of ... hiện toàn bộ
Synthesis, antiplasmodial activity and in silico molecular docking study of pinocembrin and its analogsSpringer Science and Business Media LLC - Tập 16 - Trang 1-30 - 2022
Yadessa Melaku, Melat Solomon, Rajalakshmanan Eswaramoorthy, Uwe Beifuss, Vladimir Ondrus, Yalemtsehay Mekonnen
Malaria remains the major health problem responsible for many mortality and
morbidity in developing countries. Because of the development of resistance by
Plasmodium species, searching effective antimalarial agents becomes increasingly
important. Pinocembrin is a flavanone previously isolated as the most active
antiplasmodial compound from the leaves of Dodonaea angustifolia. For a better
understa... hiện toàn bộ