Species diversity of different insect families trapped under beer-based volatile fermentationSpringer Science and Business Media LLC - Tập 14 - Trang 1-12 - 2020
Mazher Farid Iqbal, Yu-Long Feng
Insect species composition is an important phenomenon playing a significant role in the ecosystem. Chemical control of insects and pests releases toxic materials to the environment. These chemicals are dangerous to human populations. In this situation, there is a dire need to develop strategies to overcome the haphazard use of chemicals. The present investigations were carried out to explore the d...... hiện toàn bộ
Vibrational spectral analysis, XRD-structure, computation, exo⇔endo isomerization and non-linear optical crystal of 5-((5-chloro-1H-indol-2-yl)methylene)-1,3-diethyl-2-thioxodihy-dropyrimidine-4,6 (1H,5H)-dioneSpringer Science and Business Media LLC - Tập 13 - Trang 1-14 - 2019
Mezna Saleh Altowyan, Assem Barakat, Abdullah Mohammed Al-Majid, Hazem A. Ghabbour, Abdelkader Zarrouk, Ismail Warad
This work deals with the synthesis and characterization of the novel 5-((5-chloro-1H-indol-2-yl)methylene)-1,3-diethyl-2-thioxodihydro-pyrimidine-4,6(1H,5H)-dione π-bridge (D–A–D) donor–acceptor–donor compound. Its exo-isomer structure has been proven by XRD-single-crystal analysis for the first time. The IR, UV–Vis., MS, CHN-, 1H and 13C NMR analysis were also carried out. The DFT-optimized struc...... hiện toàn bộ
Effects of simulated digestion on the phenolic composition and antioxidant activity of different cultivars of lychee pericarpSpringer Science and Business Media LLC - Tập 13 - Trang 1-10 - 2019
Qingzhu Zeng, Zhuohui Xu, Mingrui Dai, Xuejiao Cao, Xiong Xiong, Shan He, Yang Yuan, Mingwei Zhang, Lihong Dong, Ruifen Zhang, Dongxiao Su
Lychee pericarp is rich in phenolic and has good antioxidant activity. The effects of simulated gastric (SGF) and intestinal fluid (SIF) digestion on the contents, composition, and antioxidant activities of the phenolic substances in the pericarp of different lychee cultivars (cv Jizui, Lizhiwang, Guiwei, Yuhe, Nuomici and Guihong) were investigated. Compared with distilled water (DW) treatment, t...... hiện toàn bộ
Indole-based FLT3 inhibitors and related scaffolds as potential therapeutic agents for acute myeloid leukemiaSpringer Science and Business Media LLC - Tập 17 - Trang 1-31 - 2023
Hend A. A. Ezelarab, Taha F. S. Ali, Samar H. Abbas, Heba A. Hassan, Eman A. M. Beshr
Fms-like tyrosine kinase 3 (FLT3) mutation mechanisms are among the most common genetic abnormalities detected in about 30% of acute myeloid leukemia (AML) patients. These mutations are accompanied by poor clinical response, although all these progressions in identifying and interpreting biological AML bio-targets. Several small structured FLT3 inhibitors have been ameliorated to struggle against ...... hiện toàn bộ
Solubility of mesalazine in pseudo-binary mixtures of choline chloride/ethylene glycol deep eutectic solvent and water at 293.15 K to 313.15 KSpringer Science and Business Media LLC - Tập 17 - Trang 1-12 - 2023
Elina Armani, Parisa Jafari, Salar Hemmati, Elaheh Rahimpour, Mohammad Barzegar-Jalali, Abolghasem Jouyban
Mesalazine (5-ASA) is a medication utilized to treat inflammatory bowel diseases involving ulcerative colitis and Crohn’s disease. Mesalazine has fewer side effects but the low solubility and bioavailability of it is responsible for its delayed onset of action. Hence, the goal of this study is to determine the molar solubility of 5-ASA in aqueous pseudo-binary mixtures containing low toxic biocomp...... hiện toàn bộ
Computational approaches: discovery of GTPase HRas as prospective drug target for 1,3-diazine scaffoldsSpringer Science and Business Media LLC - Tập 13 - Trang 1-13 - 2019
Sanjiv Kumar, Deepika Sharma, Balasubramanian Narasimhan, Kalavathy Ramasamy, Syed Adnan Ali Shah, Siong Meng Lim, Vasudevan Mani
Heterocyclic 1,3-diazine nucleus is a valuable pharmacophore in the field of medicinal chemistry and exhibit a wide spectrum of biological activities. PharmMapper, a robust online tool used for establishing the target proteins based on reverse pharmacophore mapping. PharmMapper study is carried out to explore the pharmacological activity of 1,3-diazine derivatives using reverse docking program. Ph...... hiện toàn bộ
Synthesis and biological evaluation of [131I]iodocarvedilol as a potential radiopharmaceutical for heart imagingSpringer Science and Business Media LLC -
M. A. Motaleb, K M Attalah, H. A. Shweeta, Ismail Ibrahim
AbstractThe optimization of the radiolabeling yield of carvedilol with iodine-131 was described. Dependence of the labeling yield of [131I]iodocarvedilol on the concentration of carvedilol, chloramine-T content, pH of the reaction mixture and reaction time was studied in details. Carvedilol was labeled with iodine-131 at pH 6 with a labeling yi...... hiện toàn bộ