Emerging landscape of molecular interaction networks: Opportunities, challenges and prospectsSpringer Science and Business Media LLC - Tập 47 - Trang 1-26 - 2022
Gauri Panditrao, Rupa Bhowmick, Chandrakala Meena, Ram Rup Sarkar
Network biology finds application in interpreting molecular interaction networks and providing insightful inferences using graph theoretical analysis of biological systems. The integration of computational bio-modelling approaches with different hybrid network-based techniques provides additional information about the behaviour of complex systems. With increasing advances in high-throughput techno...... hiện toàn bộ
Removal of radioactive strontium from the rat by feeding stable strontiumSpringer Science and Business Media LLC - Tập 1 - Trang 99-107 - 1979
S. G. Kshirsagar
The effect of administering the stable isotope of strontium (as phos-phate) at different dietary levels to adult rats (fed on a cereal and pulse-based diet containing 0.4% Ca) on the retention of radiostrontium (89Sr) and radiocalcium (45Ca) in the femur and the whole skeleton was studied for a period up to 6 weeks after an intraperitoneal injection of the two radioisotopes. The ability of stronti...... hiện toàn bộ
Comparison of compositional constraints: Nuclear genome vs plasmid genome of Pseudomonas syringae pv. tomato DC3000Springer Science and Business Media LLC - Tập 47 - Trang 1-14 - 2022
Yengkhom Sophiarani, Supriyo Chakraborty
Pseudomonas syringae pathovar (pv) tomato DC3000 (PsPto) causes bacterial speck disease in Solanum lycopersicum (tomato) and Arabidopsis thaliana. This bacterium has attracted a lot of attention from researchers. Codon usage bias (CUB) analysis is a helpful tool to understand the gene and genome biology of an organism and also provides insights into the evolutionary mechanism. Several studies have...... hiện toàn bộ
Molecular organization of great millet (Sorghum vulgare) DNASpringer Science and Business Media LLC - Tập 6 - Trang 795-809 - 1984
Lakshmi Sivaraman, Vidya S. Gupta, P. K. Ranjekar
Approximately 52% of the nuclear genome of great millet(Sorghum vulgare) consists of repetitive DNA which can be grouped into very fast, fast and slow components. The reiteration frequencies of the fast and slow reassociating components are {dy7000} and 92 respectively. Approximately 90% of the genome consists of repeated sequences interspersed amongst themselves and with single copy sequences. Th...... hiện toàn bộ
MiR-222 inhibition alleviates Staphylococcal Enterotoxin B-induced inflammatory acute lung injury by targeting Foxo3Springer Science and Business Media LLC - Tập 45 - Trang 1-11 - 2020
Liang Chen, Jun Chen, Guogang Xie, Limei Zhu
Acute lung injury (ALI) is a common acute and severe disease in clinical practice. Staphylococcal Enterotoxin B (SEB) is a superantigen that can cause inflammatory ALI. MiR-222 has been demonstrated to be upregulated in SEB-induced inflammatory ALI, but its exact roles and functions remain ill-defined. In this study, SEB exposure led to inflammatory ALI and high expression of miR-222 in model mice...... hiện toàn bộ
Target-specific gene delivery in plant systems and their expression: Insights into recent developmentsSpringer Science and Business Media LLC - Tập 45 - Trang 1-12 - 2020
Debdyuti Nandy, Amrita Maity, Arup Kumar Mitra
In order to improve crop plants in terms of their yield, drought resistance, pest resistance, nutritional value, etc., modern agriculture has relied upon plant genetic engineering. Since the advent of recombinant DNA technology, several tools have been used for genetic transformations in plants such as Agrobacterium tumefaciens, virus-mediated gene transfer, direct gene transfer systems such as el...... hiện toàn bộ
Proteomic analysis of cell lines to identify the irinotecan resistance proteinsSpringer Science and Business Media LLC - Tập 35 - Trang 557-564 - 2010
Xing-Chen Peng, Feng-Ming Gong, Meng Wei, Xi Chen, Ye Chen, Ke Cheng, Feng Gao, Feng Xu, Feng Bi, Ji-Yan Liu
Chemotherapeutic drug resistance is a frequent cause of treatment failure in colon cancer patients. Several mechanisms have been implicated in drug resistance. However, they are not sufficient to exhaustively account for this resistance emergence. In this study, two-dimensional gel electrophoresis (2-DE) and the PDQuest software analysis were applied to compare the differential expression of irino...... hiện toàn bộ