Kathryn M. Burleson, Linda K. Hansen, Amy P. N. Skubitz
Ovarian carcinoma patients frequently develop malignant ascites containing
single and aggregated tumor cells, or spheroids. Spheroids have been shown to be
resistant to many therapies, but their contribution to ovarian cancer
dissemination remains undetermined. We have previously shown that ascites
spheroids adhere to extracellular matrix (ECM) proteins and live human
mesothelial cells via β1 inte... hiện toàn bộ