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Revealing the concealed: A tribute to Donald L. Morton, MD
Springer Science and Business Media LLC -
S. David Nathanson, Ian Wood
Determinants of differential liver-colonizing potential of variants of the MCA-38 murine colon cancer cell line
Springer Science and Business Media LLC - Tập 13 - Trang 141-150 - 1995
James J. Piscatelli, Stephan A. Cohen, Charles S. Berensont, Peter Lance
We investigated factors that might contribute to the differing liver tumor colonizing potentials of MCA-38 colonic cancer cell line variants injected into the ileocolic veins of C57B1/6J mice. Non-colonizing (MCA-38 CD) cells were sensitive to lysis by hepatic ntural killer (NK) cells in vitro (51 Cr-release assay) and cells with high liver-colonizing potential (MCA-38 LD) were resistant. Followin...... hiện toàn bộ
Culture of PNKT-4B cells at invasion permissive and restrictive temperatures. I. Chromosomal analysis
Springer Science and Business Media LLC - Tập 8 - Trang 267-276 - 1990
J. W. Williams, M. D. Smith, D. L. Carlson, C. S. Williams, K. S. Tweedell, R. G. McKinnell
PNKT-4B is an aneuploid cell line derived from a herpesvirus-induced renal adenocarcinoma of Rana pipiens that displays restricted invasion at 21°C or cooler and invasion at 23°C through 28°C. Metaphase chromosomes obtained from subcultures (passages 297; 345–347) grown at 18°C or 28°C were Giemsa stained or N-banded with acidic silver nitrate. Cells grown at 18°C displayed a modal chromosome numb...... hiện toàn bộ
Invasion of micro-organisms
Springer Science and Business Media LLC - Tập 14 Số S1 - Trang 28-30 - 1996
Implications of tumor progression on clinical oncology
Springer Science and Business Media LLC - Tập 3 - Trang 151-188 - 1985
Danny R. Welch, S. P. Tomasovic
Differential modulation of proliferation, matrix metalloproteinase expression and invasion of human head and neck squamous carcinoma cells by c-erbB ligands
Springer Science and Business Media LLC - Tập 17 - Trang 631-639 - 1999
Pornchai O-charoenrat, Peter Rhys-Evans, William J. Court, Gary M. Box, Suzanne A. Eccles
Evidence suggests that there is an association between the abnormal expression of members of the c-erbB receptor tyrosine kinase family and poor prognosis in head and neck squamous cell carcinomas (HNSCC). Until now, the relative contributions of different c-erbB ligands to HNSCC progression have not been clearly defined. In this paper we examined the effects of ligands with different c-erbB recep...... hiện toàn bộ
Suppression of human melanoma metastasis following introduction of chromosome 6 is independent of NME1 (Nm23)
Springer Science and Business Media LLC - Tập 15 - Trang 259-265 - 1997
Mary E. Miele , Abel De La Rosa , Jeong-Hyung Lee , Deana J. Hicks , John U. Dennis , Patricia S. Steeg , Danny R. Welch
Metastasis is suppressed more than 95% following microcell-mediated transfer of a single copy of neomycin-tagged human chromosome 6 (neo6) into the human melanoma cell lines C8161 and MelJuSo. Concomitant with metastasis suppression is upregulation of NME1 (Nm23-H1) mRNA and protein expression. The purposes of this study were to determine whether NME1 expression was responsible for metastasis supp...... hiện toàn bộ
Comparison of ex vivo bioluminescence imaging, Alu-qPCR and histology for the quantification of spontaneous lung and bone metastases in subcutaneous xenograft mouse models
Springer Science and Business Media LLC - - Trang 1-13 - 2024
Marie-Therese Haider, Vera Freytag, Linda Krause, Tanja Spethmann, Tobias Gosau, Mia C. Beine, Christine Knies, Jennifer Schröder-Schwarz, Michael Horn, Kristoffer Riecken, Tobias Lange
Bioluminescence imaging (BLI) is a non-invasive state-of-the-art-method for longitudinal tracking of tumor cells in mice. The technique is commonly used to determine bone metastatic burden in vivo and also suitable ex vivo to detect even smallest bone micro-metastases in spontaneous metastasis xenograft models. However, it is unclear to which extent ex vivo BLI correlates with alternative methods ...... hiện toàn bộ
Targeting IL-6 and RANKL signaling inhibits prostate cancer growth in bone
Springer Science and Business Media LLC - Tập 31 - Trang 921-933 - 2014
Yu Zheng, Dennis Basel, Shu-Oi Chow, Colette Fong-Yee, Sarah Kim, Frank Buttgereit, Colin R. Dunstan, Hong Zhou, Markus J. Seibel
In prostate cancer metastases to bone, cancer cell-derived cytokines stimulate RANKL expression by cells of the osteoblast lineage, which in turn activates osteoclastic bone resorption. However, it is unclear whether cells of the osteoblast lineage signal back to prostate cancer cells, and if so, whether such direct cross-talk can be targeted therapeutically. Using the human prostate cancer cell l...... hiện toàn bộ
Fluid shear stress influences invasiveness of HeLa cells through the induction of autophagy
Springer Science and Business Media LLC - Tập 39 - Trang 495-504 - 2022
Joyjyoti Das, Tapas K. Maiti
Extravasation of metastatic cells from the blood or lymphatic circulation and formation of secondary tumor at a distant site is a key step of cancer metastasis. In this study, we report the role of hemodynamic shear stresses in fostering the release of pro-extravasation factors through the mediation of autophagy in cervical cancer HeLa cells. HeLa cells were exposed to physiological shear stress t...... hiện toàn bộ
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