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Revealing the concealed: A tribute to Donald L. Morton, MD
Springer Science and Business Media LLC -
S. David Nathanson, Ian Wood
Determinants of differential liver-colonizing potential of variants of the MCA-38 murine colon cancer cell line
Springer Science and Business Media LLC - Tập 13 - Trang 141-150 - 1995
James J. Piscatelli, Stephan A. Cohen, Charles S. Berensont, Peter Lance
We investigated factors that might contribute to the differing liver tumor colonizing potentials of MCA-38 colonic cancer cell line variants injected into the ileocolic veins of C57B1/6J mice. Non-colonizing (MCA-38 CD) cells were sensitive to lysis by hepatic ntural killer (NK) cells in vitro (51 Cr-release assay) and cells with high liver-colonizing potential (MCA-38 LD) were resistant. Followin...... hiện toàn bộ
Culture of PNKT-4B cells at invasion permissive and restrictive temperatures. I. Chromosomal analysis
Springer Science and Business Media LLC - Tập 8 - Trang 267-276 - 1990
J. W. Williams, M. D. Smith, D. L. Carlson, C. S. Williams, K. S. Tweedell, R. G. McKinnell
PNKT-4B is an aneuploid cell line derived from a herpesvirus-induced renal adenocarcinoma of Rana pipiens that displays restricted invasion at 21°C or cooler and invasion at 23°C through 28°C. Metaphase chromosomes obtained from subcultures (passages 297; 345–347) grown at 18°C or 28°C were Giemsa stained or N-banded with acidic silver nitrate. Cells grown at 18°C displayed a modal chromosome numb...... hiện toàn bộ
Invasion of micro-organisms
Springer Science and Business Media LLC - Tập 14 Số S1 - Trang 28-30 - 1996
Implications of tumor progression on clinical oncology
Springer Science and Business Media LLC - Tập 3 - Trang 151-188 - 1985
Danny R. Welch, S. P. Tomasovic
Differential modulation of proliferation, matrix metalloproteinase expression and invasion of human head and neck squamous carcinoma cells by c-erbB ligands
Springer Science and Business Media LLC - Tập 17 - Trang 631-639 - 1999
Pornchai O-charoenrat, Peter Rhys-Evans, William J. Court, Gary M. Box, Suzanne A. Eccles
Evidence suggests that there is an association between the abnormal expression of members of the c-erbB receptor tyrosine kinase family and poor prognosis in head and neck squamous cell carcinomas (HNSCC). Until now, the relative contributions of different c-erbB ligands to HNSCC progression have not been clearly defined. In this paper we examined the effects of ligands with different c-erbB recep...... hiện toàn bộ
Suppression of human melanoma metastasis following introduction of chromosome 6 is independent of NME1 (Nm23)
Springer Science and Business Media LLC - Tập 15 - Trang 259-265 - 1997
Mary E. Miele , Abel De La Rosa , Jeong-Hyung Lee , Deana J. Hicks , John U. Dennis , Patricia S. Steeg , Danny R. Welch
Metastasis is suppressed more than 95% following microcell-mediated transfer of a single copy of neomycin-tagged human chromosome 6 (neo6) into the human melanoma cell lines C8161 and MelJuSo. Concomitant with metastasis suppression is upregulation of NME1 (Nm23-H1) mRNA and protein expression. The purposes of this study were to determine whether NME1 expression was responsible for metastasis supp...... hiện toàn bộ
The influence of the ambient temperature on tumour growth, metastasis and survival in mice
Springer Science and Business Media LLC - Tập 6 - Trang 213-219 - 1988
W. De Neve, J. Van Der Elst, F. Geerts, R. Van Loon, V. De Clerck, G. Storme
The effect of ambient temperature was analysed on the behaviour of MO4 cells which are malignant, invasive and metastasizing C3H mouse fibroblastic cells when implanted in the tail of the syngeneic animal. Raising the ambient temperature to 28°C increases growth of the primary tumour, incidence of metastases and shortens survival. Lowering the ambient temperature to 13°C prevents all these phenome...... hiện toàn bộ
Imaging and quantifying the dynamics of tumor-associated proteolysis
Springer Science and Business Media LLC - Tập 26 - Trang 299-309 - 2008
Mansoureh Sameni, Dora Cavallo-Medved, Julie Dosescu, Christopher Jedeszko, Kamiar Moin, Stefanie R. Mullins, Mary B. Olive, Deborah Rudy, Bonnie F. Sloane
The roles of proteases in cancer are dynamic. Furthermore, the roles or functions of any one protease may differ from one stage of cancer to another. Proteases from tumor-associated cells (e.g., fibroblasts, inflammatory cells, endothelial cells) as well as from tumor cells make important contributions to ‘tumor proteolysis’. Many tumors exhibit increases in expression of proteases at the level of...... hiện toàn bộ
Comparison of ex vivo bioluminescence imaging, Alu-qPCR and histology for the quantification of spontaneous lung and bone metastases in subcutaneous xenograft mouse models
Springer Science and Business Media LLC - - Trang 1-13 - 2024
Marie-Therese Haider, Vera Freytag, Linda Krause, Tanja Spethmann, Tobias Gosau, Mia C. Beine, Christine Knies, Jennifer Schröder-Schwarz, Michael Horn, Kristoffer Riecken, Tobias Lange
Bioluminescence imaging (BLI) is a non-invasive state-of-the-art-method for longitudinal tracking of tumor cells in mice. The technique is commonly used to determine bone metastatic burden in vivo and also suitable ex vivo to detect even smallest bone micro-metastases in spontaneous metastasis xenograft models. However, it is unclear to which extent ex vivo BLI correlates with alternative methods ...... hiện toàn bộ
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