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Role of neurotrophins and neurotrophin receptors in the in vitro invasion and heparanase production of human prostate cancer cells
Springer Science and Business Media LLC - Tập 17 - Trang 307-314 - 1999
E. Timothy Walch, Dario Marchetti
The role of the neurotrophins (NTs) and their corresponding receptors (NTRs) TrkA, TrkB, TrkC, and p75NTR in neoplasia has received relatively little attention. However, because malignant cell migration within the prostate occurs predominantly by direct extension around prostatic nerves, the presence and possible upregulation of NTs from autocrine/paracrine sources and NTR expression within prosta...... hiện toàn bộ
Revealing the concealed: A tribute to Donald L. Morton, MD
Springer Science and Business Media LLC -
S. David Nathanson, Ian Wood
Is survival really better after repeated lung metastasectomy?
Springer Science and Business Media LLC - Tập 38 Số 1 - Trang 73-75 - 2021
Francesca Fiorentino, Tom Treasure
Chemically modified tetracyclines inhibit human melanoma cell invasion and metastasis
Springer Science and Business Media LLC - - 1998
Richard E. B. Seftor, Elisabeth A. Seftor, Joseph E. De Larco, David E. Kleiner, Jill Leferson, William G. Stetler-Stevenson, Thomas F. McNamara, Lorne M. Golub, Mary J. C. Hendrix
Recent work has shown that chemically modified tetracyclines (CMTs) are potent inhibitors of matrix metal-loproteinase (MMP) activity, both in vitro and in vivo, which is distinct from their antimicrobial activities (Golub et al. Crit Rev Oral Biol Med, 2, 297-321, 1991; Ryan et al. Curr Opin Rheumatol, 8, 238-47, 1996). The process of tumor cell invasion requires MMP-mediated degradation of extra...... hiện toàn bộ
A new pseudo-peptide of Arg-Gly-Asp (RGD) with inhibitory effect on tumor metastasis and enzymatic degradation of extracellular matrix
Springer Science and Business Media LLC - Tập 16 - Trang 94-104 - 1998
Hideki Fujii, Naoyuki Nishikawa, Hiroyuki Komazawa, Makoto Suzuki, Masayoshi Kojima, Isamu Itoh, Aya Obata, Koichi Ayukawa, Ichiro Azuma, Ikuo Saiki
A series of pseudo-peptide analogs of the Arg-Gly-Asp (RGD) sequence of fibronectin have been synthe-sized, and their anti-metastatic effects in mice and inhibitory effects on tumor cell invasion in vitro have been examined. The partially modified retro pseudo-peptide of RGD, Rrev-COCH2CO-D (FC-63), was more effective in inhibiting tumor metastasis than the original RGDS peptide. Replacement of th...... hiện toàn bộ
Determinants of differential liver-colonizing potential of variants of the MCA-38 murine colon cancer cell line
Springer Science and Business Media LLC - Tập 13 - Trang 141-150 - 1995
James J. Piscatelli, Stephan A. Cohen, Charles S. Berensont, Peter Lance
We investigated factors that might contribute to the differing liver tumor colonizing potentials of MCA-38 colonic cancer cell line variants injected into the ileocolic veins of C57B1/6J mice. Non-colonizing (MCA-38 CD) cells were sensitive to lysis by hepatic ntural killer (NK) cells in vitro (51 Cr-release assay) and cells with high liver-colonizing potential (MCA-38 LD) were resistant. Followin...... hiện toàn bộ
MUC1 Mediates Transendothelial Migration in vitro by Ligating Endothelial Cell ICAM-1
Springer Science and Business Media LLC - Tập 22 - Trang 475-483 - 2005
Jennifer J. Rahn, Jeffrey W. Chow, Garnet J. Horne, Brian K. Mah, Joanne T. Emerman, Pat Hoffman, Judith C. Hugh
MUC1 is a transmembrane glycoprotein expressed by normal breast epithelium and virtually all breast cancers. MUC1 is normally restricted to the apical surface of epithelia and loss of this polarized distribution in breast carcinomas is associated with lymph node metatases. Our previous work found that MUC1 can bind intercellular adhesion molecule-1 (ICAM-1), mediating adhesion of breast cancer cel...... hiện toàn bộ
Culture of PNKT-4B cells at invasion permissive and restrictive temperatures. I. Chromosomal analysis
Springer Science and Business Media LLC - Tập 8 - Trang 267-276 - 1990
J. W. Williams, M. D. Smith, D. L. Carlson, C. S. Williams, K. S. Tweedell, R. G. McKinnell
PNKT-4B is an aneuploid cell line derived from a herpesvirus-induced renal adenocarcinoma of Rana pipiens that displays restricted invasion at 21°C or cooler and invasion at 23°C through 28°C. Metaphase chromosomes obtained from subcultures (passages 297; 345–347) grown at 18°C or 28°C were Giemsa stained or N-banded with acidic silver nitrate. Cells grown at 18°C displayed a modal chromosome numb...... hiện toàn bộ
Transparent reporting of experimental parameters in assays measuring phenotypic steps in metastasis
Springer Science and Business Media LLC - - 2018
Robin Boiy, Jonas Steenbrugge, Jan Van Deun, An Hendrix, Evelyne Meyer, Olivier De Wever
Invasion of micro-organisms
Springer Science and Business Media LLC - Tập 14 Số S1 - Trang 28-30 - 1996
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