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Role of Gut Microbiota, Probiotics and Prebiotics in the Cardiovascular Diseases
Springer Science and Business Media LLC - Tập 26 Số 4 - Trang 1172
Anna Oniszczuk, Tomasz Oniszczuk, Marek Gancarz, Jolanta Szymańska
In recent years, there has been a growing interest in identifying and applying new, naturally occurring molecules that promote health. Probiotics are defined as “live microorganisms which, when administered in adequate amounts, confer health benefits on the host”. Quite a few fermented products serve as the source of probiotic strains, with many factors influencing the effectiveness of pro...... hiện toàn bộ
Stereoselective Palladium(II)–Catalyzed Oxycarbonylation of Unsaturated Polyols
Springer Science and Business Media LLC - - 1997
Tibor Gracza, L’uboš Remeň, Peter Szolcsányi, Volker Jäger, Thomas Hasenöhrl
Synthesis and Antimicrobial Activity of Some New Thieno[2,3-b]thiophene Derivatives
Springer Science and Business Media LLC - Tập 18 Số 4 - Trang 4669-4678
Yahia N. Mabkhot, Nabila A. Kheder, Ahmad S. Shawali
A series of thieno[2,3-b]thiophene moiety-containing bis-cyanopyrazoles 5a–c, bis-aminopyrazole 9 and bis-pyridazine derivatives 11 were synthesized and evaluated in vitro for their antimicrobial potential. The antimicrobial activity of some selected products was evaluated and showed good results. 5,5'-(3,4-Dimethylthieno[2,3-b]thiophene-2,5-diyl)bis(3-acetyl-1-(4-chlorophenyl)-1H-pyrazole...... hiện toàn bộ
The Feasibility of Enzyme Targeted Activation for Amino Acid/Dipeptide Monoester Prodrugs of Floxuridine; Cathepsin D as a Potential Targeted Enzyme
Springer Science and Business Media LLC - Tập 17 Số 4 - Trang 3672-3689
Yasuhiro Tsume, Gordon L. Amidon
The improvement of therapeutic efficacy for cancer agents has been a big challenge which includes the increase of tumor selectivity and the reduction of adverse effects at non-tumor sites. In order to achieve those goals, prodrug approaches have been extensively investigated. In this report, the potential activation enzymes for 5¢-amino acid/dipeptide monoester floxuridine prodrugs in panc...... hiện toàn bộ
Melatonin as a Potent and Inducible Endogenous Antioxidant: Synthesis and Metabolism
Springer Science and Business Media LLC - Tập 20 Số 10 - Trang 18886-18906
Dun-Xian Tan, Lucien C. Manchester, Eduardo Esteban‐Zubero, Zhou Zhou, Rüssel J. Reiter
Melatonin is a tryptophan-derived molecule with pleiotropic activities. It is present in almost all or all organisms. Its synthetic pathway depends on the species in which it is measured. For example, the tryptophan to melatonin pathway differs in plants and animals. It is speculated that the melatonin synthetic machinery in eukaryotes was inherited from bacteria as a result of endosymbios...... hiện toàn bộ
Silymarin Constituents Enhance ABCA1 Expression in THP-1 Macrophages
Springer Science and Business Media LLC - Tập 21 Số 1 - Trang 55
Limei Wang, Susanne Rotter, Angela Ladurner, Elke H. Heiß, Nicholas H. Oberlies, Verena M. Dirsch, Atanas G. Atanasov
Silymarin is a hepatoprotective mixture of flavonolignans and flavonoids extracted from the seeds of milk thistle (Silybum marianum L. Gaertn). This study investigates the effect of major bioactive constituents from silymarin, silybin A, silybin B, isosilybin A, isosilybin B, silydianin, silychristin, isosilychristin, and taxifolin, on the expression of ABCA1, an important cholesterol effl...... hiện toàn bộ
Supercritical Fluid Extraction of Plant Flavors and Fragrances
Springer Science and Business Media LLC - Tập 18 Số 6 - Trang 7194-7238
Andrea Capuzzo, Massimo E. Maffei, Andrea Occhipinti
Supercritical fluid extraction (SFE) of plant material with solvents like CO2, propane, butane, or ethylene is a topic of growing interest. SFE allows the processing of plant material at low temperatures, hence limiting thermal degradation, and avoids the use of toxic solvents. Although today SFE is mainly used for decaffeination of coffee and tea as well as production of hop extracts on a...... hiện toàn bộ
Precursor-Dependent Photocatalytic Activity of Carbon Dots
Springer Science and Business Media LLC - Tập 25 Số 1 - Trang 101
Emanuele Amadio, Simone Cailotto, Carlotta Campalani, Lorenzo Branzi, Carlotta Raviola, Davide Ravelli, Elti Cattaruzza, Enrico Trave, A. Benedetti, Maurizio Selva, Alvise Perosa
This work systematically compares both structural features and photocatalytic performance of a series of graphitic and amorphous carbon dots (CDs) prepared in a bottom-up manner from fructose, glucose, and citric acid. We demonstrate that the carbon source and synthetic procedures diversely affect the structural and optical properties of the CDs, which in turn unpredictably influence their...... hiện toàn bộ
Purification and Characterization of Antioxidant Peptides of Pseudosciaena crocea Protein Hydrolysates
Springer Science and Business Media LLC - Tập 22 Số 1 - Trang 57
Ningning Zhang, Chong Zhang, Yuanyuan Chen, Baodong Zheng
Two peptides with antioxidant activity were isolated from Pseudosciaena crocea proteins. Pseudosciaena crocea muscle was hydrolyzed with neutral protease to obtain Pseudosciaena crocea protein hydrolysates (PCPH). After ultrafiltration through molecular weight cut-off membranes of 10, 5 and 3 kDa and assessment of free radical scavenging ability, the fraction (PCPH-IV) with the highest ant...... hiện toàn bộ
Chemical Fingerprint and Multicomponent Quantitative Analysis for the Quality Evaluation of Cyclocarya paliurus Leaves by HPLC–Q–TOF–MS
Springer Science and Business Media LLC - Tập 22 Số 11 - Trang 1927
Yanni Cao, Shengzuo Fang, Zhiqi Yin, Xiangxiang Fu, Xulan Shang, Wanxia Yang, Huimin Yang
Cyclocarya paliurus is an edible and medicinal plant containing various bioactive components with significant health benefits. A combinative method using high-performance liquid chromatography (HPLC) fingerprint and quantitative analysis was developed and successfully applied for characterization and quality evaluation of C. paliurus leaves collected from 18 geographical locations of China...... hiện toàn bộ
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