Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal Tập 6 Số 269 - 2013
Jianjiong Gao, Bülent Arman Aksoy, Uğur Doğrusöz, Gideon Dresdner, Benjamin Groß, S. Onur Sumer, Yichao Sun, Anders J. Skanderup, Rileen Sinha, Erik Larsson, Ethan Cerami, Chris Sander, Nikolaus Schultz
The cBioPortal enables integration, visualization, and analysis of multidimensional cancer genomic and clinical data.
Delivery of MicroRNA-126 by Apoptotic Bodies Induces CXCL12-Dependent Vascular Protection Tập 2 Số 100 - 2009
Alma Zernecke, Kiril Bidzhekov, Heidi Noels, Erdenechimeg Shagdarsuren, Lin Gan, Bernd Denecke, Mihail Hristov, Thomas Köppel, Maliheh Nazari-Jahantigh, Esther Lutgens, Shusheng Wang, Eric N. Olson, Andreas Schober, Christian Weber
Apoptotic endothelial cells release microRNA-containing microvesicles to modulate the responses of neighboring cells and reduce atherosclerosis in mice.
H 2 S Signals Through Protein S-Sulfhydration Tập 2 Số 96 - 2009
Asif K. Mustafa, Moataz M. Gadalla, Nilkantha Sen, Seyun Kim, Weitong Mu, Sadia K. Gazi, Roxanne K. Barrow, Guangdong Yang, Rui Wang, Solomon H. Snyder
The gaseous messenger hydrogen sulfide regulates target proteins through S-sulfhydration of cysteine residues.
System-Wide Changes to SUMO Modifications in Response to Heat Shock Tập 2 Số 72 - 2009
Filip Gołębiowski, Ivan Matić, Michael H. Tatham, Christian Cole, Yili Yin, Akihiro Nakamura, Jürgen Cox, Geoffrey J. Barton, Matthias Mann, Ronald T. Hay
The small ubiquitin-like modifier protein SUMO is redistributed among many targets to mediate both short- and long-term signaling events.
Tissue Inhibitors of Metalloproteinases in Cell Signaling: Metalloproteinase-Independent Biological Activities Tập 1 Số 27 - 2008
William G. Stetler‐Stevenson
Over the past 20 years, the tissue inhibitors of metalloproteinases (TIMPs) have been implicated in direct regulation of cell growth and apoptosis. However, the mechanisms of these effects have been controversial. Recent work by several laboratories has identified specific signaling pathways and cell surface binding partners for members of the TIMP family. TIMP-2 binding to th...... hiện toàn bộ
Linear Motif Atlas for Phosphorylation-Dependent Signaling Tập 1 Số 35 - 2008
Martin L. Miller, Lars Juhl Jensen, Francesca Diella, Claus Jørgensen, Michele Tinti, Lei Li, Marilyn S. Hsiung, Sirlester A. Parker, Jennifer Bordeaux, Thomas Sicheritz‐Pontén, Marina Olhovsky, Adrian Pasculescu, Jes Alexander, Stefan Knapp, Nikolaj Blom, Peer Bork, Shawn Li, Gianni Cesareni, Tony Pawson, Benjamin E. Turk, Michael B. Yaffe, Søren Brunak, Rune Linding
Created with both in vitro and in vivo data, NetPhorest is an atlas of consensus sequence motifs for 179 kinases and 104 phosphorylation-dependent binding domains and reveals new insight into phosphorylation-dependent signaling.
Signaling by Gasotransmitters Tập 2 Số 68 - 2009
Asif K. Mustafa, Moataz M. Gadalla, Solomon H. Snyder
Nitric oxide, carbon monoxide, and hydrogen sulfide act as messengers in the cardiovascular, immune, and nervous systems.