Effect of FPZ, a total flavonoids ointment topical application from Pouzolzia zeylanica var. microphylla, on mice skin infectionsRevista Brasileira de Farmacognosia - Tập 28 - Trang 732-737 - 2018
Xian-Mei Chen, Zhi-Hui Li, Shu-Hong Tao, Yan-Fen Chen, Zhuo-Han Chen, Li-Bing Guo
The present study was designed to investigate the effect of FPZ, a total flavonoids ointment topical application from Pouzolzia zeylanica var. microphylla (Wedd.) Masam, Urticaceae, on skin infections in mice. FPZ ointment anti-infective effect was investigated on Staphylococcus aureus-induced skin abscess and skin ulcers in mice by evaluating the variation in abscess volume, histopathology of ski...... hiện toàn bộ
Growth inhibition of human breast cancer cells and down-regulation of ODC1 and ADA genes by Nepeta binaloudensisRevista Brasileira de Farmacognosia - Tập 27 - Trang 84-90 - 2016
Akbar Safipour Afshar, Fatemeh Saeid Nematpour, Mahshid Meshkani, Arezosadat Khafi
Nepeta binaloudensis Jamzad, Lamiaceae, is a rare medicinal plant endemic to Iran. In spite of many studies about the chemical constituents and antibacterial effects of this species, no report has been provided about its cytotoxic and anticancer activities. In this study we have evaluated the effects of EtOH 70%, hexane and aqueous extracts of N. binaloudensis on the cell proliferation and n-hexan...... hiện toàn bộ
Evaluation of acetylcholinesterase inhibitory activity of Brazilian red macroalgae organic extractsRevista Brasileira de Farmacognosia - Tập 25 - Trang 657-662 - 2015
Levi P. Machado, Luciana R. Carvalho, Maria Cláudia M. Young, Elaine M. Cardoso-Lopes, Danilo C. Centeno, Leonardo Zambotti-Villela, Pio Colepicolo, Nair S. Yokoya
Alzheimer’s disease affects nearly 36.5 million people worldwide, and acetylcholinesterase inhibition is currently considered the main therapeutic strategy against it. Seaweed biodiversity in Brazil represents one of the most important sources of biologically active compounds for applications in phytotherapy. Accordingly, this study aimed to carry out a quantitative and qualitative assessment of H...... hiện toàn bộ
Embriotoxic and Antioxidant Effects of Cymbopogon citratus Leaf Volatile Oil on ZebrafishRevista Brasileira de Farmacognosia - Tập 33 - Trang 778-789 - 2023
Kiara Cândido Duarte da Silva, Bárbara do Carmo Rodrigues Virote, Maria de Fátima Santos, Tássia Flávia Dias Castro, Moisés Silvestre de Azevedo Martins, William Franco Carneiro, Luis David Solis Murgas
This study aimed to characterize the phytochemical composition and in vivo embryotoxic potential of Cymbopogon citratus Stapf, Poaceae, volatile oil in zebrafish (Danio rerio) embryos. Volatile oil was obtained by steam distillation and analysed using gas chromatography-mass spectrometry. Embryotoxicity was assessed using eight concentrations (50, 25, 12.5, 6.25, 3.12, 1.56, 0.78, and 0.39 μg/ml) ...... hiện toàn bộ
Antinociceptive Effect of Volatile Oils from Ocimum basilicum Flowers on Adult ZebrafishRevista Brasileira de Farmacognosia - Tập 31 - Trang 282-289 - 2021
Francisco Lucas A. Batista, José Ismael F. de Araújo, Sandra Maria B. de Araújo, Daniela Braga de Sousa, Francisco Bastos C. Sobrinho, Franciglauber Silva Bezerra, Maria Gabriely de Lima Silva, Maria Rayane C. de Oliveira, Roger Henrique S. da Costa, Lindaiane Bezerra Rodrigues, Francisco Ernani A. Magalhães, Henrique Douglas Melo Coutinho, Irwin Rose Alencar de Menezes
The species Ocimum basilicum L., Lamiaceae, is popular for culinary purposes and medicinal use as a larvicide, repellent, antifungal, and antimicrobial agent. Therefore, the aim of the present study is to evaluate the chemical composition and antinociceptive effect of the volatile oil of O. basilicum flowers using adult zebrafish (Danio rerio) (n = 6/group) treated orally (20 µl) with volatile oil...... hiện toàn bộ
Vitamin K: a Potential Neuroprotective AgentRevista Brasileira de Farmacognosia - Tập 33 - Trang 676-687 - 2023
Kaberi Chatterjee, Papiya Mitra Mazumder, Sugato Banerjee
Neurodegeneration, a progressive disease due to the arrested development of atrophy and regression of neuron function, is the most common disorder people go through. The treatment of the disease is generally symptomatic, and after a certain time, the effectivity of the drug decreases. A less toxic compound, vitamin K, a lipophilic (fat-soluble) vitamin, shows some promising results. Generally, vit...... hiện toàn bộ