Obesity, obstructive sleep apnoea and metabolic syndromeRespirology - Tập 17 Số 2 - Trang 223-236 - 2012
Jamie C.M. Lam, Jcw Mak, Msm Ip
ABSTRACTOSA is increasingly recognized as a major health problem in developed countries. Obesity is the most common risk factor in OSA and hence, the prevalence of OSA is undoubtedly rising given the epidemic of obesity. Recent data also suggest that OSA is highly associated with the metabolic syndrome, and it is postulated that OSA contributes to cardiometabolic d...... hiện toàn bộ
The immunology of tuberculosis: From bench to bedsideRespirology - Tập 15 Số 3 - Trang 433-450 - 2010
Keertan Dheda, Stephan Schwander, Bingdong Zhu, Richard N. van Zyl-Smit, Ying Zhang
ABSTRACTTuberculosis (TB) is an international public health priority and kills almost two million people annually. TB is out of control in Africa due to increasing poverty and HIV coinfection, and drug‐resistant TB threatens to destabilize TB control efforts in several regions of the world. Existing diagnostic tools and therapeutic interventions for TB are suboptim...... hiện toàn bộ
Correlates of erectile dysfunction in moderate‐to‐severe chronic obstructive pulmonary disease patientsRespirology - Tập 12 Số 2 - Trang 248-253 - 2007
Fisun Karadağ, H. Nursun Özcan, Aslıhan Karul, Emel Ceylan, Orhan Çildağ
Objective and background: Erectile dysfunction (ED) has important negative effects on male quality of life and self‐esteem. The aim of this study was to acquire an insight into the sexual status of COPD patients.Methods: Ninety‐five male patients aged 48–75 years, with moderate‐to‐severe stable COPD, and 30 age‐matched subjec...... hiện toàn bộ
Interferon‐γ responses after isoniazid chemotherapy for latent tuberculosisRespirology - Tập 13 Số 3 - Trang 468-472 - 2008
Kazue Higuchi, Nobuyuki Harada, Toru Mori
Background and objective: Chemotherapy for Mycobacterium tuberculosis infection may decrease interferon (IFN)‐γ responses to early secretory antigenic target 6 and culture filtrate protein (CFP)‐10; a reaction that could be useful to monitor the success of treatment. We investigated IFN‐γ responses in subjects with latent TB infection befo...... hiện toàn bộ
Women and tobaccoRespirology - Tập 8 Số 2 - Trang 123-130 - 2003
Judith Mackay, Amanda Amos
Abstract: Smoking prevalence is lower among women than men in most countries, yet there are about 200 million women in the world who smoke, and in addition, there are millions more who chew tobacco. Approximately 22% of women in developed countries and 9% of women in developing countries smoke, but because most women live in developing countries, there are numerical...... hiện toàn bộ
Histological diagnosis of interstitial lung diseases by cryo‐transbronchial biopsyRespirology - Tập 19 Số 5 - Trang 683-688 - 2014
Oren Fruchter, Ludmila Fridel, Bayya Abed El Raouf, Nader Abdel‐Rahman, Dror Rosengarten, Mordechai R. Kramer
AbstractBackground and objectiveThe gold standard for the histological diagnosis of interstitial lung diseases (ILD) is an open lung biopsy (OLB). Tissue samples obtained by forceps transbronchial lung biopsi...... hiện toàn bộ
The role of acute and chronic respiratory colonization and infections in the pathogenesis of COPDRespirology - Tập 22 Số 4 - Trang 634-650 - 2017
Janice M. Leung, Pei Yee Tiew, Micheál Mac Aogáin, Kurtis F. Budden, V. Wee Yong, Sajan Thomas, Kévin Pethe, Philip M. Hansbro, Sanjay H. Chotirmall
ABSTRACT
COPD is a major global concern, increasingly so in the context of ageing populations. The role of infections in disease pathogenesis and progression is known to be important, yet the mechanisms involved remain to be fully elucidated. While COPD... hiện toàn bộ
Bronchial epithelial cells: The key effector cells in the pathogenesis of chronic obstructive pulmonary disease?Respirology - Tập 20 Số 5 - Trang 722-729 - 2015
Wei Gao, Ling‐Ling Li, Yujie Wang, Sini Zhang, Ian M. Adcock, Peter J. Barnes, Mao Huang, Xin Yao
AbstractThe primary function of the bronchial epithelium is to act as a defensive barrier aiding the maintenance of normal airway function. Bronchial epithelial cells (BEC) form the interface between the external environment and the internal milieu, making it a major target of inhaled insults. However, <...... hiện toàn bộ