Respirology

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The immunology of tuberculosis: From bench to bedside
Respirology - Tập 15 Số 3 - Trang 433-450 - 2010
Keertan Dheda, Stephan Schwander, Bingdong Zhu, Richard N. van Zyl-Smit, Ying Zhang
ABSTRACTTuberculosis (TB) is an international public health priority and kills almost two million people annually. TB is out of control in Africa due to increasing poverty and HIV coinfection, and drug‐resistant TB threatens to destabilize TB control efforts in several regions of the world. Existing diagnostic tools and therapeutic interventions for TB are suboptim...... hiện toàn bộ
MUC5AC and inflammatory mediators associated with respiratory outcomes in the British 1946 birth cohort
Respirology - Tập 18 Số 6 - Trang 1003-1010 - 2013
Lauren Johnson, Syed Imran Ali Shah, Andrew Loh, Lynne E. Vinall, Ana Teixeira, Karine Rousseau, John W. Holloway, Rebecca Hardy, Dallas M. Swallow
AbstractBackground and objectiveDysregulation of respiratory mucins, MUC5AC in particular, has been implicated in respiratory disease and MUC5AC expression is up‐regulated in respon...... hiện toàn bộ
Invasive pulmonary aspergillosis associated with influenza B
Respirology - Tập 10 Số 1 - Trang 116-119 - 2005
Nobuchika Hasejima, Kunio Yamato, Shinji Takezawa, Hiroaki Kobayashi, Chikabumi Kadoyama
Abstract:  Invasive pulmonary aspergillosis (IPA) usually occurs in immunocompromised patients. However, rarely, this infection can occur in normal hosts. This review of the literature identified 13 cases of IPA associated with influenza, of which 12 had influenza A and the type of influenza was not mentioned in the other case. Reported here is a case of IPA, which w...... hiện toàn bộ
Long‐term follow‐up after bronchoscopic lung volume reduction treatment with coils in patients with severe emphysema
Respirology - Tập 20 Số 2 - Trang 319-326 - 2015
Jorine E. Hartman, Karin Klooster, Kiki Gortzak, Nick H.T. ten Hacken, Dirk‐Jan Slebos
AbstractBackground and objectiveBronchoscopic lung volume reduction coil (LVR‐coil) treatment has been shown to be safe and clinically effective in patients with severe emphysema in the short term; however, long‐term safety and effectiveness has not been evaluated. The ...... hiện toàn bộ
Springing forward to medium‐term results for endobronchial coils for emphysema
Respirology - Tập 20 Số 2 - Trang 176-178 - 2015
Pallav L. Shah, Samuel V. Kemp
Heat shock response decreases endotoxin‐induced acute lung injury in rats
Respirology - Tập 4 Số 4 - Trang 325-330 - 1999
Younsuck Koh, Chae‐Man Lim, Mi Jung Kim, Tae Sun Shim, Sang‐Do Lee, Woo Sung Kim, Dong‐Soon Kim, Wondong Kim
Objective:Transient whole‐body hyperthermia was reported to reduce lung damage in a rat with intra‐abdominal sepsis produced by caecal perforation. Methodology: In order to determine the effect of heat shock response on acute lung injury induced by endotoxin, which plays a central role in the pathogenes...... hiện toàn bộ
Exhaled nitric oxide continues to reflect airway hyperresponsiveness and disease activity in inhaled corticosteroid‐treated adult asthmatic patients
Respirology - Tập 8 Số 4 - Trang 479-486 - 2003
David W. Reid, DP Johns, Bryce Feltis, Chris Ward, E. Haydn Walters
Objective:  Exhaled nitric oxide (eNO) has been used as a surrogate of airway inflammation in mild asthma. However, whether eNO levels reflect disease activity in symptomatic asthmatics receiving moderate doses of inhaled corticosteroid (ICS) is more uncertain.Methodology:  To examine the relationship between eNO levels, sputum...... hiện toàn bộ
Investigation of the association between dietary intake, disease severity and airway inflammation in asthma
Respirology - Tập 18 Số 3 - Trang 447-454 - 2013
Bronwyn S. Berthon, Lesley MacDonald‐Wicks, Peter G. Gibson, Lisa G. Wood
AbstractBackground and objectiveDietary intake is an important modifiable risk factor for asthma and may be related to disease severity and inflammation, through the effects of intake of anti‐oxidant‐rich foods and pro‐inflammatory nutrients. This study aimed to examine dietary intake in asthma in relation to asthma severity, lung...... hiện toàn bộ
Obesity, obstructive sleep apnoea and metabolic syndrome
Respirology - Tập 17 Số 2 - Trang 223-236 - 2012
Jamie C.M. Lam, Jcw Mak, Msm Ip
ABSTRACTOSA is increasingly recognized as a major health problem in developed countries. Obesity is the most common risk factor in OSA and hence, the prevalence of OSA is undoubtedly rising given the epidemic of obesity. Recent data also suggest that OSA is highly associated with the metabolic syndrome, and it is postulated that OSA contributes to cardiometabolic d...... hiện toàn bộ
Clinical significance of serum hyaluronan in chronic fibrotic interstitial pneumonia
Respirology - Tập 18 Số 8 - Trang 1236-1243 - 2013
Yayoi Inokoshi, Yoshinori Tanino, Xintao Wang, Suguru Sato, Naoko Fukuhara, Takefumi Nikaido, Atsuro Fukuhara, Junpei Saito, Charles W. Frevert, Mitsuru Munakata
AbstractBackground and objectiveHyaluronan is an important constituent of the extracellular matrix in lungs, and growing evidence demonstrates its important biological properties in the lung. However, its role in interstitial pneumonia remains to be fully clarified. The goal of this study was to clarify the role of hyaluronan in i...... hiện toàn bộ
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