Pleiades Publishing Ltd
SCOPUS (2007-2022)ESCI-ISI
1990-7508
1990-7516
Cơ quản chủ quản: MAIK NAUKA-INTERPERIODICA , Pleiades Publishing
Lĩnh vực:
Clinical BiochemistryMolecular MedicineBiochemistry
Các bài báo tiêu biểu
Biosensor analysis of the interaction of potential dimerization inhibitors with HIV-1 protease
- 2009
Synthesis and hypoglycemic activity of Bis(L-malato)oxovanadium(IV)
Tập 5 - Trang 260-262 - 2011
In order to create new oral vanadyl organic complexes-based drugs for the treatment of diabetes mellitus we have originally synthesized a biligand vanadyl derivative of L-malic acid (bis(L-malato)oxovanadium(IV)) and investigated its potential as a novel hypoglycemic agent using the experimental streptozotocin-induced diabetes in rats. The oral administration of bis(L-malato)oxovanadium(IV) with drinking water significantly reduced blood and urinary glucose concentrations and also the level of glycated proteins in the streptozotocin-diabetic rats.