Systemic inflammation and cardiac surgery: an update Tập 16 Số 5 - Trang 353-360 - 2001
George Asimakopoulos
Cardiac surgery with cardiopulmonary bypass (CPB) is associated with the
development of a systemic inflammatory response that can often lead to
dysfunction of major organs. The systemic inflammation can be assessed intra-
and postoperatively by measuring concentrations of inflammatory mediators in
plasma and tissues. These concentrations, however, do not always correlate with
the degree of observe... hiện toàn bộ
Red blood cell transfusion volume and mortality among patients receiving extracorporeal membrane oxygenation Tập 28 Số 1 - Trang 54-60 - 2013
Andrew Smith, DC Hardison, B. Berly Bridges, Pietsch Jb
Background: Red blood cell (RBC) transfusion is used in the critically ill with
low hemoglobin concentrations to optimize oxygen utilization and delivery
imbalance. Data suggest that RBC transfusion is also independently associated
with significant morbidity. We seek to characterize RBC transfusion volumes
among patients receiving extracorporeal membrane oxygenation (ECMO) support and
test the hyp... hiện toàn bộ
Mini extracorporeal circuit for coronary artery bypass grafting: initial clinical and biochemical results Tập 19 Số 4 - Trang 239-246 - 2004
David Breen, Wim B. Gerritsen, Frans G. Waanders, Fred J.L.M. Haas
Background: The new concept of mini-extracorporeal circulation (MECC) for
coronary artery bypass grafts (MCABG) consists of minimal priming volume, a
heparin-coated closed circuit, a centrifugal pump, active drainage, blood
cardioplegia and a cell-saving device. The potential organ protective effect of
this technique during CABG is unknown. Initial clinical outcomes, oxidative
stress, alveolar shu... hiện toàn bộ
A comparison study of haemolysis production in three contemporary centrifugal pumps Tập 29 Số 5 - Trang 411-416 - 2014
Steve Bottrell, Martin R. Bennett, S Augustin, Clarke A. Thuys, Bradley Schultz, Allison M. Horton, Stephen Horton
One challenge in providing extracorporeal circulation is to supply optimal flow
while minimising adverse effects, such as haemolysis. To determine if the recent
generation constrained vortex pumps with their inherent design improvements
would lead to reduced red cell trauma, we undertook a study comparing three
devices. Utilizing a simulated short-term ventricular assist circuit primed with
whole ... hiện toàn bộ
Cardioplegic strategies to protect the hypertrophic heart during cardiac surgery Tập 26 Số 1_suppl - Trang 48-56 - 2011
M.Saadeh Suleiman, Matthew Hancock, Ratnesh K. Shukla, Cha Rajakaruna, Gianni D. Angelini
Cardioplegic arrest and cardiopulmonary bypass are key triggers of myocardial
injury during aortic valve surgery. Cardioplegic ischaemic arrest is associated
with disruption to metabolic and ionic homeostasis in cardiomyocytes. These
changes predispose the heart to reperfusion injury caused by elevated
intracellular reactive oxygen species and calcium. Cardiopulmonary bypass is
associated with an ... hiện toàn bộ
Hỗ trợ ECMO trong hội chứng viêm đa hệ thống liên quan đến SARS-CoV-2 ở trẻ em Dịch bởi AI Tập 36 Số 5 - Trang 524-528 - 2021
Shubhi Kaushik, Neha Ahluwalia, Sandeep Gangadharan, Maria Esperenza, Raghav Murthy, George Ofori‐Amanfo, Scott I. Aydin
Trong báo cáo này, chúng tôi mô tả trường hợp bệnh nhân nam, 5 tuổi, mắc hội
chứng viêm đa hệ thống liên quan đến SARS-CoV-2 với suy hô hấp tiến triển và sốc
mất trương lực mạch máu, cần hỗ trợ ngoài cơ thể tuần hoàn (ECMO). Khi nhập
viện, kết quả xét nghiệm phiên mã ngược-polymerase chuỗi (RT-PCR) cho SARS-CoV-2
là âm tính, tuy nhiên kết quả xét nghiệm kháng thể SARS-CoV-2 là dương tính.
Nhiều dấ... hiện toàn bộ
#Hội chứng viêm đa hệ thống #ECMO #SARS-CoV-2 #nhi khoa #suy hô hấp #sốc mất trương lực #đột quỵ
A recovery model of partial cardiopulmonary bypass in the rat Tập 16 Số 3 - Trang 215-220 - 2001
Olivier Fabre, Rachid Zegdi, André Vincentelli, Michèle Cambillaud, Alain Prat, Alain Carpentier, Jean‐Noël Fabiani
This study was undertaken to develop a recovery model of cardiopulmonary bypass
(CPB) in rats. Twenty male Wistar rats (475-550 g) were anaesthetized,
mechanically ventilated and the femoral vessels cannulated. The extracorporeal
circulation circuit comprised a roller pump, a venous reservoir and a modified
Capiox 308 paediatric membrane oxygenator. Priming consisted of 20 ml of fresh
homologous b... hiện toàn bộ
Expression of soluble endothelial adhesion molecules in clinical cardiopulmonary bypass Tập 13 Số 5 - Trang 314-321 - 1998
Joseph Galea, Naomi Rebuck, Adam Finn, A. Manché, Neil Moat
Soluble endothelial adhesion molecule expression in clinical cardiopulmonary
bypass (CPB) was investigated. Neutrophil-mediated endothelial injury plays an
important role in CPB-induced organ dysfunction. The adhesion of neutrophil to
the endothelium is central to this process. It has been well documented that CPB
induces neutrophil activation and changes in neutrophil adhesion molecule
expression... hiện toàn bộ
Impact of cardiopulmonary bypass on peripheral tissue metabolism and microvascular blood flow Tập 23 Số 6 - Trang 339-346 - 2008
Jiří Manďák, Marek Pojar, Norbert Cibicek, Vladimír Lonský, Vladimír Palička, D Kakrdová, J Nedvı́dková, J Kubíček, Pavel Živný
The aim of this study was to monitor and compare the changes in metabolism and
blood flow in the skeletal muscles during cardiac operations performed with
cardiopulmonary bypass (CPB) and operations without CPB (off-pump) by means of
interstitial microdialysis (Figure 1). Surgical revascularization, coronary
artery bypass grafting (CABG), was performed in 40 patients randomized to two
groups. Twen... hiện toàn bộ