Systemic inflammation and cardiac surgery: an update Tập 16 Số 5 - Trang 353-360 - 2001
George Asimakopoulos
Cardiac surgery with cardiopulmonary bypass (CPB) is associated with the development of a systemic inflammatory response that can often lead to dysfunction of major organs. The systemic inflammation can be assessed intra- and postoperatively by measuring concentrations of inflammatory mediators in plasma and tissues. These concentrations, however, do not always correlate with the degree o...... hiện toàn bộ Mini extracorporeal circuit for coronary artery bypass grafting: initial clinical and biochemical results Tập 19 Số 4 - Trang 239-246 - 2004
David Breen, Wim B. Gerritsen, Frans G. Waanders, Fred J.L.M. Haas
Background: The new concept of mini-extracorporeal circulation (MECC) for coronary artery bypass grafts (MCABG) consists of minimal priming volume, a heparin-coated closed circuit, a centrifugal pump, active drainage, blood cardioplegia and a cell-saving device. The potential organ protective effect of this technique during CABG is unknown. Initial clinical outcomes, oxidative stress, alv...... hiện toàn bộ A comparison study of haemolysis production in three contemporary centrifugal pumps Tập 29 Số 5 - Trang 411-416 - 2014
Steve Bottrell, Martin R. Bennett, S Augustin, Clarke A. Thuys, Bradley Schultz, Allison M. Horton, Stephen Horton
One challenge in providing extracorporeal circulation is to supply optimal flow while minimising adverse effects, such as haemolysis. To determine if the recent generation constrained vortex pumps with their inherent design improvements would lead to reduced red cell trauma, we undertook a study comparing three devices. Utilizing a simulated short-term ventricular assist circuit primed wi...... hiện toàn bộ Cardioplegic strategies to protect the hypertrophic heart during cardiac surgery Tập 26 Số 1_suppl - Trang 48-56 - 2011
M.Saadeh Suleiman, Matthew Hancock, Ratnesh K. Shukla, Cha Rajakaruna, Gianni D. Angelini
Cardioplegic arrest and cardiopulmonary bypass are key triggers of myocardial injury during aortic valve surgery. Cardioplegic ischaemic arrest is associated with disruption to metabolic and ionic homeostasis in cardiomyocytes. These changes predispose the heart to reperfusion injury caused by elevated intracellular reactive oxygen species and calcium. Cardiopulmonary bypass is associated...... hiện toàn bộ Hỗ trợ ECMO trong hội chứng viêm đa hệ thống liên quan đến SARS-CoV-2 ở trẻ em Dịch bởi AI Tập 36 Số 5 - Trang 524-528 - 2021
Shubhi Kaushik, Neha Ahluwalia, Sandeep Gangadharan, Maria Esperenza, Raghav Murthy, George Ofori‐Amanfo, Scott I. Aydin
Trong báo cáo này, chúng tôi mô tả trường hợp bệnh nhân nam, 5 tuổi, mắc hội chứng viêm đa hệ thống liên quan đến SARS-CoV-2 với suy hô hấp tiến triển và sốc mất trương lực mạch máu, cần hỗ trợ ngoài cơ thể tuần hoàn (ECMO). Khi nhập viện, kết quả xét nghiệm phiên mã ngược-polymerase chuỗi (RT-PCR) cho SARS-CoV-2 là âm tính, tuy nhiên kết quả xét nghiệm kháng thể SARS-CoV-2 là dương tính. Nhiều dấ...... hiện toàn bộ #Hội chứng viêm đa hệ thống #ECMO #SARS-CoV-2 #nhi khoa #suy hô hấp #sốc mất trương lực #đột quỵ
A recovery model of partial cardiopulmonary bypass in the rat Tập 16 Số 3 - Trang 215-220 - 2001
Olivier Fabre, Rachid Zegdi, André Vincentelli, Michèle Cambillaud, Alain Prat, Alain Carpentier, Jean‐Noël Fabiani
This study was undertaken to develop a recovery model of cardiopulmonary bypass (CPB) in rats. Twenty male Wistar rats (475-550 g) were anaesthetized, mechanically ventilated and the femoral vessels cannulated. The extracorporeal circulation circuit comprised a roller pump, a venous reservoir and a modified Capiox 308 paediatric membrane oxygenator. Priming consisted of 20 ml of fresh hom...... hiện toàn bộ Expression of soluble endothelial adhesion molecules in clinical cardiopulmonary bypass Tập 13 Số 5 - Trang 314-321 - 1998
Joseph Galea, Naomi Rebuck, Adam Finn, A. Manché, Neil Moat
Soluble endothelial adhesion molecule expression in clinical cardiopulmonary bypass (CPB) was investigated. Neutrophil-mediated endothelial injury plays an important role in CPB-induced organ dysfunction. The adhesion of neutrophil to the endothelium is central to this process. It has been well documented that CPB induces neutrophil activation and changes in neutrophil adhesion molecule e...... hiện toàn bộ Impact of cardiopulmonary bypass on peripheral tissue metabolism and microvascular blood flow Tập 23 Số 6 - Trang 339-346 - 2008
Jiří Manďák, Marek Pojar, Norbert Cibicek, Vladimír Lonský, Vladimír Palička, D Kakrdová, J Nedvı́dková, J Kubíček, Pavel Živný
The aim of this study was to monitor and compare the changes in metabolism and blood flow in the skeletal muscles during cardiac operations performed with cardiopulmonary bypass (CPB) and operations without CPB (off-pump) by means of interstitial microdialysis (Figure 1). Surgical revascularization, coronary artery bypass grafting (CABG), was performed in 40 patients randomized to two gro...... hiện toàn bộ