A comparison study of haemolysis production in three contemporary centrifugal pumps
Tóm tắt
One challenge in providing extracorporeal circulation is to supply optimal flow while minimising adverse effects, such as haemolysis. To determine if the recent generation constrained vortex pumps with their inherent design improvements would lead to reduced red cell trauma, we undertook a study comparing three devices. Utilizing a simulated short-term ventricular assist circuit primed with whole human blood, we examined changes in plasma free haemoglobin values over a six-day period. The three pumps investigated were the Maquet Rotaflow, the Levitronix PediVAS and the Medos Deltastream DP3.This study demonstrated that all three pumps produced low levels of haemolysis and are suitable for use in a clinical environment. The Levitronix PediVAS was significantly less haemolytic than either the Rotaflow (p<0.05) or the DP3 (p<0.05). There was no significant difference in plasma free haemoglobin between the Rotaflow and the DP3 (p=0.71).
Từ khóa
Tài liệu tham khảo
Conrad S, 2012, ECMO. Extracorporeal cardiopulmonary support in critical care, 4, 102
Levitronix Technologies. Bearingless pump technology. http://www.levitronix.com/en/Bearingless_Pumps.html (2010, accessed June 2013)
Schöb R. Centrifugal pump without bearings or seals. http://www.worldpumps.com (2002, Retrieved June 2013)
Medos Medizintechnik AG, 2013, Stolberg Germany MEDOS Medizintechnik AG
Petermann H, 2005, Strömungsmaschinen, 7