Induction of haem oxygenase‐1 increases infection of dog macrophages by L. infantumParasite Immunology - Tập 39 Số 12 - 2017
Breno Fernando Martins de Almeida, K. L. O. Silva, Gabriela Lovizutto Venturin, Vanessa Marin Chiku, Aline Aparecida Correa Leal, Anelise Maria Bosco, Paulo César Ciarlini, Valéria Marçal Felix de Lima
SummaryWe aimed to induce and inhibit HO‐1, ascertaining its effect on infection rate, parasite load and the levels of superoxide, reactive oxygen species (ROS), nitric oxide (NO), ...... hiện toàn bộ
Immunization against malaria with a recombinant proteinParasite Immunology - Tập 16 Số 2 - Trang 63-67 - 1994
Irene T. Ling, Solabomi A. Ogun, Anthony A. Holder
SUMMARYWe have expressed in bacteria the C‐terminal part of Plasmodium yoelii merozoite surface protein‐1 (MSP1) containing the two epidermal growth factor‐like domains. The protein, either alone or fused to glutathione Stransferase, was highly effective as a vaccine and protected mice against challenge infection. Reduction and alkylation...... hiện toàn bộ
Infection with Schistosoma mansoni prevents insulin dependent diabetes mellitus in non‐obese diabetic miceParasite Immunology - Tập 21 Số 4 - Trang 169-176 - 1999
Anne Cooke, Paul Tonks, Frances J. Jones, Helen O’Shea, Patricia Hutchings, Anthony J. C. Fulford, David W. Dunne
The spontaneous development of insulin dependent diabetes mellitus in non‐obese diabetic (NOD) mice has been shown to be mediated by a Th1 response against beta cell antigens. It is known that in murine models of Schistosoma mansoni infection, egg production is associated with a switch from a Th1 to Th2 response. This subsequent dominance of a Th2 r...... hiện toàn bộ
Haemonchus contortus intestine: a prominent source of mucosal antigensParasite Immunology - Tập 29 Số 3 - Trang 139-151 - 2007
Douglas P. Jasmer, Kevin K. Lahmers, Wendy C. Brown
SUMMARY We sought to identify antigens from Haemonchus contortus, an abomasal nematode of small ruminants, that stimulate local (abomasal lymph node, ALN) CD4+ T lymphocyte responses during a primary infection. Results led to a focus on antigens from the parasite intestine. The H. contortus intestin...... hiện toàn bộ
Protease‐activated receptor 2 contributes to Toxoplasma gondii‐mediated gut inflammationParasite Immunology - Tập 39 Số 11 - 2017
Chrystelle Bonnart, Guylène Feuillet, Virginie Vasseur, Nicolas Cénac, Nathalie Vergnolle, Nicolas Blanchard
SummaryToxoplasma gondii is a widespread intracellular parasite, which naturally enters the organism via the oral route and crosses the intestinal barrier to disseminate. In addition to neuronal and ocular pathologies, this pathogen also causes gut inflammation in a number of animals. This infection‐triggered inflammation has been extensi...... hiện toàn bộ
The gut mucosal immune response to Toxoplasma gondiiParasite Immunology - Tập 37 Số 3 - Trang 108-117 - 2015
Sara Cohen, Eric Denkers
SummaryAs an orally acquired pathogen, the immune response to Toxoplasma gondii unfolds in the small intestinal mucosa. There, an array of regulatory and effector immune cells are elicited to combat the parasite through secretion of inflammatory mediators, normally resulting in host protection and pathogen control. Recent studies largely ...... hiện toàn bộ