PLoS Genetics

  1553-7390

  1553-7404

  Mỹ

Cơ quản chủ quản:  PUBLIC LIBRARY SCIENCE , Public Library of Science

Lĩnh vực:
Cancer ResearchEcology, Evolution, Behavior and SystematicsGeneticsGenetics (clinical)Molecular Biology

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Thông tin về tạp chí

 

Genetics and genomics research has grown at a bewildering pace in the past 15 years. The techniques of these fields are being applied to a wealth of biological questions and experimental systems. PLOS Genetics reflects the full breadth and interdisciplinary nature of this research by publishing outstanding original contributions in all areas of biology. PLOS Genetics publishes human studies, as well as research on model organisms—from mice and flies, to plants and bacteria. Our emphasis is on studies of broad interest that provide significant insight into a biological process or processes. Topics include (but are not limited to) gene discovery and function, population genetics, genome projects, comparative and functional genomics, medical genetics, disease biology, evolution, gene expression, complex traits, chromosome biology, and epigenetics.

Các bài báo tiêu biểu

Delayed and Accelerated Aging Share Common Longevity Assurance Mechanisms
Tập 4 Số 8 - Trang e1000161
Björn Schumacher, Ingrid van der Pluijm, Michael Moorhouse, Theodoros Kosteas, Andria Rasile Robinson, Yousin Suh, Timo M. Breit, Harry van Steeg, Laura J. Niedernhofer, Wilfred F. J. van IJcken, Andrzej Bartke, Stephen R. Spindler, Jan H.J. Hoeijmakers, Arjen van Ooyen, George A. Garinis
Double Strand Breaks Can Initiate Gene Silencing and SIRT1-Dependent Onset of DNA Methylation in an Exogenous Promoter CpG Island
Tập 4 Số 8 - Trang e1000155
Heather M. O’Hagan, Helai P. Mohammad, Stephen B. Baylin
Transcriptional profiling of aging in human muscle reveals a common aging signature
Tập preprint Số 2006 - Trang e115 - 2005
Jacob M. Zahn, Rebecca Sonu, Hannes Vogel, Emily Crane, Krystyna Mazan-Mamczarz, Ralph Rabkin, Ron Davis, Kevin G. Becker, Art B. Owen, Stuart K. Kim
Lifespan Regulation by Evolutionarily Conserved Genes Essential for Viability
Tập 3 Số 4 - Trang e56
Sean P. Curran, Gary Ruvkun
AGEMAP: A Gene Expression Database for Aging in Mice
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Jacob M. Zahn, Suresh Poosala, Art B. Owen, Donald K. Ingram, Ana Lustig, Arnell Carter, Ashani T. Weeraratna, Dennis D. Taub, Myriam Gorospe, Krystyna Mazan-Mamczarz, Edward G. Lakatta, Kenneth R. Boheler, X.Z. Shawn Xu, Mark P. Mattson, Geppino Falco, Minoru S.H. Ko, David Schlessinger, Jeffrey Firman, Sarah Kummerfeld, William H. Wood, Alan B. Zonderman, Stuart K. Kim, Kevin G. Becker
Acute Versus Chronic Loss of Mammalian Azi1/Cep131 Results in Distinct Ciliary Phenotypes
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Emma A. Hall, Margaret Keighren, Matthew J. Ford, Tracey Davey, Andrew P. Jarman, Lee B. Smith, Ian J. Jackson, Pleasantine Mill
Motor and Sensory Deficits in the teetering Mice Result from Mutation of the ESCRT Component HGS
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Jennifer A. Watson, Bula J. Bhattacharyya, Jada H Vaden, Julie A. Wilson, Mert Icyuz, Alan D. Howard, Edward Phillips, Tara M. DeSilva, Gene P. Siegal, Andrew J. Bean, Gwendalyn D. King, Scott E. Phillips, Richard J. Miller, Scott M. Wilson
Cell-Type Specific Features of Circular RNA Expression
Tập 9 Số 9 - Trang e1003777
Julia Salzman, Raymond Chen, Mari Olsen, Peter L. Wang, Patrick O. Brown
Paralog buffering contributes to the variable essentiality of genes in cancer cell lines
Tập 15 Số 10 - Trang e1008466
Barbara De Kegel, Colm J. Ryan
Genic Intolerance to Functional Variation and the Interpretation of Personal Genomes
Tập 9 Số 8 - Trang e1003709
Slavé Petrovski, Quanli Wang, Erin L. Heinzen, Andrew S. Allen, David B. Goldstein