PLoS Genetics

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Identifying Signatures of Natural Selection in Tibetan and Andean Populations Using Dense Genome Scan Data
PLoS Genetics - Tập 6 Số 9 - Trang e1001116
Abigail W. Bigham, Marc Bauchet, Dalila Pinto, Xianyun Mao, Joshua M. Akey, Rui Mei, Stephen W. Scherer, Colleen G. Julian, Megan J. Wilson, David López Herráez, Tom D. Brutsaert, Esteban J. Parra, Lorna G. Moore, Mark D. Shriver
Requirements for F-BAR Proteins TOCA-1 and TOCA-2 in Actin Dynamics and Membrane Trafficking during Caenorhabditis elegans Oocyte Growth and Embryonic Epidermal Morphogenesis
PLoS Genetics - Tập 5 Số 10 - Trang e1000675
Chiara Giuliani, Flavia Troglio, Zhiyong Bai, Falshruti B. Patel, Adriana Zucconi, Maria Grazia Malabarba, Andrea Disanza, Theresia E. B. Stradal, Giuseppe Cassata, Stefano Confalonieri, Jeffrey D. Hardin, Martha C. Soto, Barth D. Grant, Giorgio Scita
MIG-10 Functions with ABI-1 to Mediate the UNC-6 and SLT-1 Axon Guidance Signaling Pathways
PLoS Genetics - Tập 8 Số 11 - Trang e1003054
Yan Xu, Christopher C. Quinn
Pleiotropic Associations of Allelic Variants in a 2q22 Region with Risks of Major Human Diseases and Mortality
PLoS Genetics - Tập 12 Số 11 - Trang e1006314
Alexander M. Kulminski, Liang He, Irina Culminskaya, Yury Loika, Yelena Kernogitski, Konstantin G. Arbeev, Elena Loiko, Liubov Arbeeva, Olivia Bagley, Matt Duan, Arseniy Yashkin, Fang Fang, Mikhail Kovtun, Svetlana Ukraintseva, Deqing Wu, Anatoliy I. Yashin
Positive Selection Drives the Evolution of rhino, a Member of the Heterochromatin Protein 1 Family in Drosophila
PLoS Genetics - Tập 1 Số 1 - Trang e9
Danielle Vermaak, Steven Henikoff, Harmit S. Malik
Conserved piRNA Expression from a Distinct Set of piRNA Cluster Loci in Eutherian Mammals
PLoS Genetics - Tập 11 Số 11 - Trang e1005652
Gung-Wei Chirn, Reazur Rahman, Yuliya A. Sytnikova, Jessica Matts, Mei Zeng, Daniel Gerlach, Michael Yu, Bonnie Berger, Lei Duan, Benjamin T. Kile, Nelson C. Lau
Comparing the DNA Hypermethylome with Gene Mutations in Human Colorectal Cancer
PLoS Genetics - Tập 3 Số 9 - Trang e157
Kornel E. Schuebel, Wei Chen, Leslie Cope, Sabine C. Glöckner, Hiromu Suzuki, Joo Mi Yi, Timothy A. Chan, Leander Van Neste, Wim Van Criekinge, Sandra van den Bosch, Manon van Engeland, Angela H. Ting, Kamwing Jair, Wayne Yu, Minoru Toyota, Kohzoh Imai, Joseph M. Herman, James G. Herman, Stephen B. Baylin
Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with Systemic Lupus Erythematosus
PLoS Genetics - Tập 7 Số 10 - Trang e1002341
Deborah S. Cunninghame Graham, David Morris, Tushar Bhangale, Lindsey A. Criswell, Johanna K. Sandling, Lars Rönnblom, Timothy W. Behrens, Robert Graham, Timothy J. Vyse
Population Structure and Eigenanalysis
PLoS Genetics - Tập 2 Số 12 - Trang e190 - 2006
Nick Patterson, Alkes L. Price, David Reich
Human genome diversity data reveal that L564P is the predominant TPC2 variant and a prerequisite for the blond hair associated M484L gain-of-function effect
PLoS Genetics - Tập 17 Số 1 - Trang e1009236
Julia Böck, Einar Krogsaeter, Marcel Passon, Yu‐Kai Chao, Sapna Sharma, Harald Grallert, Annette Peters, Christian Grimm
The endo-lysosomal two-pore channel (TPC2) has been established as an intracellular cation channel of significant physiological and pathophysiological relevance in recent years. For example, TPC2-/- mice show defects in cholesterol degradation, leading to hypercholesterinemia; TPC2 absence also results in mature-onset obesity, and a role in glucagon secretion and diabetes has been proposed. Infect... hiện toàn bộ
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