Oxford University Press (OUP)
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A prospective study of time to healing and hypertrophic scarring in paediatric burns: every day counts
Oxford University Press (OUP) - Tập 5 - Trang 1-6 - 2017
It is commonly accepted that burns taking longer than 3 weeks to heal have a much higher rate of hypertrophic scarring than those which heal more quickly. However, some of our patients develop hypertrophic scars despite healing within this 3-week period. We performed a prospective study of 383 paediatric burns treated non-operatively at a regional burns centre over a 2-year period from May 2011 to......
Current progress of skin tissue engineering: Seed cells, bioscaffolds, and construction strategies
Oxford University Press (OUP) - Tập 1 - Trang 63-72 - 2013
The development of cell biology, molecular biology, and material science, has been propelling biomimic tissue-engineered skins to become more sophisticated in scientificity and more simplified in practicality. In order to improve the safety, durability, elasticity, biocompatibility, and clinical efficacy of tissue-engineered skin, several powerful seed cells have already found their application in......
Current progress in understanding the molecular pathogenesis of burn scar contracture
Oxford University Press (OUP) - Tập 5 - Trang 1-6 - 2017
Abnormal wound healing is likely to induce scar formation, leading to dysfunction, deformity, and psychological trauma in burn patients. Despite the advancement of medical care treatment, scar contracture in burn patients remains a challenge. Myofibroblasts play a key role in scar contracture. It has been demonstrated that myofibroblasts, as well as inflammatory cells, fibroblasts, endothelial cel......
Morphometric evaluation of wound healing in burns treated with Ulmo (Eucryphia cordifolia) honey alone and supplemented with ascorbic acid in guinea pig (Cavia porcellus)Abstract Background In the context of the search for cost-efficient treatments, Ulmo (Eurcyphia cordifolia) honey is an excellent alternative for treating burn wounds and could have a profound medical, social, and economic impact. Ascorbic acid is an enzymatic co-factor necessary for the synthesis of collagen and the proliferation o...
Oxford University Press (OUP) - - 2016
A systematic and quantitative method for wound-dressing evaluation
Oxford University Press (OUP) - Tập 3 - Trang 1-8 - 2015
For patients with skin defects such as burns, wound dressing plays important roles in protecting the wound. Before a novel wound dressing is applied to a patient, a series of tests should be performed to ensure its safety and efficacy. Different types of animal wound-healing models have been used to study the bio-function of different wound dressings; however, a systematic way to evaluate the effe......
Comparative effectiveness of Biobrane®, RECELL® Autologous skin Cell suspension and Silver dressings in partial thickness paediatric burns: BRACS randomised trial protocolAbstract
Background
Mixed partial thickness burns are the most common depth of burn injury managed at a large Australian paediatric hospital specialty burns unit. Prolonged time until re-epithelialisation is associated with increased burn depth and scar formation. Whilst current ... ...
Oxford University Press (OUP) - Tập 7 - 2019
A case study of blast eye injury at work place
Oxford University Press (OUP) - Tập 1 - Trang 140-143 - 2013
This case report aims at investigating whether two consecutive surgical settings would be beneficial in achieving postoperative success for the patient with blast eye injury. A 45-year-old male patient admitted on 17th October 2011 with history of blast eye injury. Right eye examination revealed central corneal laceration with incarceration of lens matter, multiple foreign bodies also seen embedde......
Pre-expanded occipito-dorsal flap reconstruction for neck burns: A novel approach
Oxford University Press (OUP) - Tập 2 - Trang 88-90 - 2014
Reconstruction of the neck following a burn injury poses a significant challenge to reconstructive burn surgeons. Here, we report a case of successful application of pre-expanded occipito-dorsal flaps in the reconstruction of postburn scars and contractures in the neck. The patient was a 10-year-old boy who sustained scars and contractures secondary to a burn injury 4 years ago. “Super-thin” flaps......
Topical antimicrobial agents for pediatric burns
Oxford University Press (OUP) - Tập 5 - Trang 1-8 - 2017
While topical antimicrobial agents are indicated for most if not all burn wounds, the choice of a topical agent must consider many factors such as the wound depth, anticipated time to healing, need for surgical intervention, and the known cytotoxicity of the agent. Especially relevant to the pediatric burn patient are the antimicrobial agent’s properties related to causing pain or irritation and t......
Development of a heart rate variability and complexity model in predicting the need for life-saving interventions amongst trauma patients
Oxford University Press (OUP) - Tập 7 - Trang 1-11 - 2019
Triage trauma scores are utilised to determine patient disposition, interventions and prognostication in the care of trauma patients. Heart rate variability (HRV) and heart rate complexity (HRC) reflect the autonomic nervous system and are derived from electrocardiogram (ECG) analysis. In this study, we aimed to develop a model incorporating HRV and HRC, to predict the need for life-saving interve......
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