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A prospective study of time to healing and hypertrophic scarring in paediatric burns: every day counts
Oxford University Press (OUP) - Tập 5 - Trang 1-6 - 2017
Elizabeth Chipp, Lisa Charles, Clare Thomas, Kate Whiting, Naiem Moiemen, Yvonne Wilson
It is commonly accepted that burns taking longer than 3 weeks to heal have a much higher rate of hypertrophic scarring than those which heal more quickly. However, some of our patients develop hypertrophic scars despite healing within this 3-week period. We performed a prospective study of 383 paediatric burns treated non-operatively at a regional burns centre over a 2-year period from May 2011 to...... hiện toàn bộ
Đánh giá có hệ thống các phương pháp đo lường khách quan sẹo bỏng Dịch bởi AI
Oxford University Press (OUP) - - 2016
Kwang Chear Lee, Janine Dretzke, Liam Grover, Ann Logan, Naiem Moiemen
Sẹo bỏng có vấn đề vẫn là một khía cạnh khó khăn trong điều trị và có thể ảnh hưởng đáng kể đến chất lượng cuộc sống của những người sống sót sau bỏng. Hiện nay, có rất ít phương pháp điều trị có sẵn trong lâm sàng để kiểm soát sẹo không mong muốn, nhưng các chiến lược chống sẹo dược lý thử nghiệm đang bắt đầu xuất hiện. Sự thành công tương đối của chúng phải được dựa trên các phép đo khách quan c...... hiện toàn bộ
Unstable cardiac injury complicated with septic shock—a challenge
Oxford University Press (OUP) - - 2016
Neha Garg, Kapil Dev Soni, Richa Aggarwal
Abstract Background Road traffic accident accounts for 70 % to 80 % of the blunt cardiac injury. The true incidence varies in the literature due to non-uniform criteria for diagnosis. Case...... hiện toàn bộ
Current progress of skin tissue engineering: Seed cells, bioscaffolds, and construction strategies
Oxford University Press (OUP) - Tập 1 - Trang 63-72 - 2013
Huanjing Bi, Yan Jin
The development of cell biology, molecular biology, and material science, has been propelling biomimic tissue-engineered skins to become more sophisticated in scientificity and more simplified in practicality. In order to improve the safety, durability, elasticity, biocompatibility, and clinical efficacy of tissue-engineered skin, several powerful seed cells have already found their application in...... hiện toàn bộ
Intralesional injection treatment of hypertrophic scars and keloids: a systematic review regarding outcomes
Oxford University Press (OUP) - Tập 3 - Trang 1-10 - 2015
Aurelia Trisliana Perdanasari, Matteo Torresetti, Luca Grassetti, Fabio Nicoli, Yi Xin Zhang, Talal Dashti, Giovanni Di Benedetto, Davide Lazzeri
The aim of this review was to explore the existing body of literature focusing on the intralesional treatments of keloids and hypertrophic scars. A comprehensive systematic review of related articles was conducted across multiple databases. Article selection was limited to those published in the English language between 1950 and 2014. Search terms for the on-line research were “scar(s),” “keloid(s...... hiện toàn bộ
Current understanding of tyrosine kinase BMX in inflammation and its inhibitors
Oxford University Press (OUP) - Tập 2 - Trang 121-124 - 2014
Le Qiu, Fei Wang, Sheng Liu, Xu-Lin Chen
Tec family kinases, which include tyrosine kinase expressed in hepatocellular carcinoma (TEC), Bruton’s tyrosine kinase (BTK), interleukin (IL)-2-inducible T-cell kinase (ITK), tyrosine-protein kinase (TXK), and bone marrow tyrosine kinase on chromosome X (BMX), are the second largest group of non-receptor tyrosine kinases and have a highly conserved carboxyl-terminal kinase domain. BMX was identi...... hiện toàn bộ
Post-burn breast reconstruction using an artificial dermis—a long-term follow-up
Oxford University Press (OUP) - Tập 4 - Trang 1-4 - 2016
Yoav Gronovich, Adi Maisel Lotan, Meir Retchkiman
Full thickness burns of the chest in childhood are a devastating problem that requires challenging reconstructive options. Integra is a bilaminate artificial dermis composed of shark chondroitin 6-sulfate and bovine collagen. The dermal matrix serves as a scaffold for fibroblasts and endothelial cells. Vascularization of the matrix begins after 2–3 weeks, and eventually, the matrix incorporates wi...... hiện toàn bộ
Body image in paediatric burns: a review
Oxford University Press (OUP) - Tập 6 - Trang 1-6 - 2018
Ian C. C. King
Burn injuries in children can result in life-long disfigurement. As medical and surgical techniques of burn management improve survival prospects more than ever before, body image adjustment is increasingly a central consideration in the care of burn-injured individuals. An appreciation that both physiological and psychosocial processes underpin such injuries is key to understanding wound healing....... hiện toàn bộ
Modifications of traditional pressure gloves for improved performance in scar flexion contracture prevention and fingertip circulation inspection
Oxford University Press (OUP) - Tập 2 - Trang 146-147 - 2014
Hongliang Zhao, Yan Chen, Cuiping Zhang, Xiaobing Fu
Current progress in understanding the molecular pathogenesis of burn scar contracture
Oxford University Press (OUP) - Tập 5 - Trang 1-6 - 2017
Jianglin Tan, Jun Wu
Abnormal wound healing is likely to induce scar formation, leading to dysfunction, deformity, and psychological trauma in burn patients. Despite the advancement of medical care treatment, scar contracture in burn patients remains a challenge. Myofibroblasts play a key role in scar contracture. It has been demonstrated that myofibroblasts, as well as inflammatory cells, fibroblasts, endothelial cel...... hiện toàn bộ
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