Neural Development
SCIE-ISI SCOPUS (2006-2023)
1749-8104
Cơ quản chủ quản: BioMed Central Ltd. , BMC
Lĩnh vực:
Developmental Neuroscience
Các bài báo tiêu biểu
Secreted APP regulates the function of full-length APP in neurite outgrowth through interaction with integrin beta1Abstract
Background
β-Amyloid precursor protein (APP) has been reported to play a role in the outgrowth of neurites from cultured neurons. Both cell-surface APP and its soluble, ectodomain cleavage product (APPs-α) have been implicated in regulating the length and branching of neurites in a varie... ...
Tập 3 Số 1 - 2008
Context-dependent functions of specific microRNAs in neuronal development
Tập 5 Số 1 - Trang 25 - 2010
Sp8 exhibits reciprocal induction with Fgf8 but has an opposing effect on anterior-posterior cortical area patterningAbstract
Telencephalic patterning centers, defined by the discrete expression domains of distinct morphogens, Fgf s in the commissural plate (CoP), Wnt s and Bmp s in the cortical hem, and a ventral domain of Sonic hedgehog (Shh ), are postulated to ... ...
Tập 2 Số 1 - 2007
Glypican-1 controls brain size through regulation of fibroblast growth factor signaling in early neurogenesisAbstract Background Cell surface heparan sulfate proteoglycans (HSPGs) act as co-receptors for multiple families of growth factors that regulate animal cell proliferation, differentiation and patterning. Elimination of heparan sulfate during brain development is known to produce severe structural abnormalities. Here we investigate t...
- 2009
Meningeal cells and glia establish a permissive environment for axon regeneration after spinal cord injury in newtsAbstract
Background
Newts have the remarkable ability to regenerate their spinal cords as adults. Their spinal cords regenerate with the regenerating tail after tail amputation, as well as after a gap-inducing spinal cord injury (SCI), such as a complete transection. While most studies on newt sp... ...
- 2011
Semaphorin-6A controls guidance of corticospinal tract axons at multiple choice pointsAbstract
Background
The trajectory of corticospinal tract (CST) axons from cortex to spinal cord involves a succession of choice points, each of which is controlled by multiple guidance molecules. To assess the involvement of transmembrane semaphorins and their plexin receptors in the guidance of... ...
- 2008
Developmental patterning of glutamatergic synapses onto retinal ganglion cellsAbstract Background Neurons receive excitatory synaptic inputs that are distributed across their dendritic arbors at densities and with spatial patterns that influence their output. How specific synaptic distributions are attained during development is not well understood. The distribution of glutamatergic inputs across the dendriti...
- 2008
Brain asymmetry is encoded at the level of axon terminal morphologyAbstract
Background
Functional lateralization is a conserved feature of the central nervous system (CNS). However, underlying left-right asymmetries within neural circuitry and the mechanisms by which they develop are poorly described.
... ...
- 2008
Spinal cord regeneration in Xenopus tadpoles proceeds through activation of Sox2-positive cellsAbstract
Background
In contrast to mammals, amphibians, such as adult urodeles (for example, newts) and anuran larvae (for example, Xenopus ) can regenerate their spinal cord after injury. However, the cellular and molecular mechanisms involved in this process are still ... ...
- 2012
The chemokine receptor cxcr5 regulates the regenerative neurogenesis response in the adult zebrafish brainAbstract
Background
Unlike mammals, zebrafish exhibits extensive neural regeneration after injury in adult stages of its lifetime due to the neurogenic activity of the radial glial cells. However, the genes involved in the regenerative neurogenesis response of the zebrafish brain are largely unkn... ...
Tập 7 Số 1 - 2012