Neural Development

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Tcf7L2 is essential for neurogenesis in the developing mouse neocortex
Neural Development - Tập 13 - Trang 1-10 - 2018
Olga Chodelkova, Jan Masek, Vladimir Korinek, Zbynek Kozmik, Ondrej Machon
Generation of neurons in the embryonic neocortex is a balanced process of proliferation and differentiation of neuronal progenitor cells. Canonical Wnt signalling is crucial for expansion of radial glial cells in the ventricular zone and for differentiation of intermediate progenitors in the subventricular zone. We detected abundant expression of two transcrtiption factors mediating canonical Wnt ...... hiện toàn bộ
The BTB/POZ zinc finger protein Broad-Z3 promotes dendritic outgrowth during metamorphic remodeling of the peripheral stretch receptor dbd
Neural Development - Tập 6 - Trang 1-16 - 2011
Janet A Scott, Darren W Williams, James W Truman
Various members of the family of BTB/POZ zinc-finger transcription factors influence patterns of dendritic branching. One such member, Broad, is notable because its BrZ3 isoform is widely expressed in Drosophila in immature neurons around the time of arbor outgrowth. We used the metamorphic remodeling of an identified sensory neuron, the dorsal bipolar dendrite sensory neuron (dbd), to examine the...... hiện toàn bộ
Eph/Ephrin Signaling Controls Progenitor Identities In The Ventral Spinal Cord
Neural Development - Tập 12 - Trang 1-11 - 2017
Julien Laussu, Christophe Audouard, Anthony Kischel, Poincyane Assis-Nascimento, Nathalie Escalas, Daniel J. Liebl, Cathy Soula, Alice Davy
In the vertebrate spinal cord, motor neurons (MN) are generated in stereotypical numbers from a pool of dedicated progenitors (pMN) whose number depends on signals that control their specification but also their proliferation and differentiation rates. Although the initial steps of pMN specification have been extensively studied, how pMN numbers are regulated over time is less well characterized. ...... hiện toàn bộ
Linking neuronal lineage and wiring specificity
Neural Development - Tập 13 - Trang 1-19 - 2018
Hongjie Li, S. Andrew Shuster, Jiefu Li, Liqun Luo
Brain function requires precise neural circuit assembly during development. Establishing a functional circuit involves multiple coordinated steps ranging from neural cell fate specification to proper matching between pre- and post-synaptic partners. How neuronal lineage and birth timing influence wiring specificity remains an open question. Recent findings suggest that the relationships between li...... hiện toàn bộ
Dynamic Pax6 expression during the neurogenic cell cycle influences proliferation and cell fate choices of retinal progenitors
Neural Development - Tập 4 - Trang 1-19 - 2009
Yi-Wen Hsieh, Xian-Jie Yang
The paired homeobox protein Pax6 is essential for proliferation and pluripotency of retinal progenitors. However, temporal changes in Pax6 protein expression associated with the generation of various retinal neurons have not been characterized with regard to the cell cycle. Here, we examine the dynamic changes of Pax6 expression among chicken retinal progenitors as they progress through the neurog...... hiện toàn bộ
Ultrabithorax confers spatial identity in a context-specific manner in the Drosophila postembryonic ventral nervous system
Neural Development - Tập 7 Số 1 - Trang 31 - 2012
Elizabeth C. Marin, Katie E Dry, Danielle R Alaimo, Kirstin Rudd, Anthony R. Cillo, Michael E. Clenshaw, Nicolas Négre, Kevin P. White, James W. Truman
Midline crossing is not required for subsequent pathfinding decisions in commissural neurons
Neural Development - Tập 7 - Trang 1-13 - 2012
Jennifer Bonner, Michael Letko, Oliver Brant Nikolaus, Lisa Krug, Alexandria Cooper, Benjamin Chadwick, Phoebe Conklin, Amy Lim, Chi-Bin Chien, Richard I Dorsky
Growth cone navigation across the vertebrate midline is critical in the establishment of nervous system connectivity. While midline crossing is achieved through coordinated signaling of attractive and repulsive cues, this has never been demonstrated at the single cell level. Further, though growth cone responsiveness to guidance cues changes after crossing the midline, it is unclear whether midlin...... hiện toàn bộ
Development, functional organization, and evolution of vertebrate axial motor circuits
Neural Development - Tập 13 - Trang 1-12 - 2018
Kristen P. D’Elia, Jeremy S. Dasen
Neuronal control of muscles associated with the central body axis is an ancient and essential function of the nervous systems of most animal species. Throughout the course of vertebrate evolution, motor circuits dedicated to control of axial muscle have undergone significant changes in their roles within the motor system. In most fish species, axial circuits are critical for coordinating muscle ac...... hiện toàn bộ
Secreted APP regulates the function of full-length APP in neurite outgrowth through interaction with integrin beta1
Neural Development - Tập 3 Số 1 - 2008
Tracy L. Young‐Pearse, Allen Ching-Way Chen, Rui B. Chang, César Márquez, Dennis J. Selkoe
Abstract Background β-Amyloid precursor protein (APP) has been reported to play a role in the outgrowth of neurites from cultured neurons. Both cell-surface APP and its soluble, ectodomain cleavage product (APPs-α) have been implicated in regulating the length and branching of neurites in a varie...... hiện toàn bộ
Correction: A single-cell transcriptomic atlas of complete insect nervous systems across multiple life stages
Neural Development - Tập 17 - Trang 1-2 - 2022
Marc Corrales, Benjamin T. Cocanougher, Andrea B. Kohn, Jason D. Wittenbach, Xi S. Long, Andrew Lemire, Albert Cardona, Robert H. Singer, Leonid L. Moroz, Marta Zlatic
Tổng số: 280   
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