Amplification of neural stem cell proliferation by intermediate progenitor cells in Drosophila brain developmentNeural Development - Tập 3 - Trang 1-18 - 2008
Bruno C Bello, Natalya Izergina, Emmanuel Caussinus, Heinrich Reichert
In the mammalian brain, neural stem cells divide asymmetrically and often amplify the number of progeny they generate via symmetrically dividing intermediate progenitors. Here we investigate whether specific neural stem cell-like neuroblasts in the brain of Drosophila might also amplify neuronal proliferation by generating symmetrically dividing intermediate progenitors. Cell lineage-tracing and g...... hiện toàn bộ
Electroporation-based methods for in vivo, whole mount and primary culture analysis of zebrafish brain developmentNeural Development - Tập 2 - Trang 1-11 - 2007
Michael Hendricks, Suresh Jesuthasan
Electroporation is a technique for the introduction of nucleic acids and other macromolecules into cells. In chick embryos it has been a particularly powerful technique for the spatial and temporal control of gene expression in developmental studies. Electroporation methods have also been reported for Xenopus, zebrafish, and mouse. We present a new protocol for zebrafish brain electroporation. Usi...... hiện toàn bộ
Olfactory discrimination largely persists in mice with defects in odorant receptor expression and axon guidanceNeural Development - Tập 7 - Trang 1-14 - 2012
Thomas K Knott, Pasil A Madany, Ashley A Faden, Mei Xu, Jörg Strotmann, Timothy R Henion, Gerald A Schwarting
The defining feature of the main olfactory system in mice is that each olfactory sensory neuron expresses only one of more than a thousand different odorant receptor genes. Axons expressing the same odorant receptor converge onto a small number of targets in the olfactory bulb such that each glomerulus is made up of axon terminals expressing just one odorant receptor. It is thought that this preci...... hiện toàn bộ
FGF signaling controls Shh-dependent oligodendroglial fate specification in the ventral spinal cordNeural Development - Tập 13 - Trang 1-19 - 2018
Marie-Amélie Farreny, Eric Agius, Sophie Bel-Vialar, Nathalie Escalas, Nagham Khouri-Farah, Chadi Soukkarieh, Cathy Danesin, Fabienne Pituello, Philippe Cochard, Cathy Soula
Most oligodendrocytes of the spinal cord originate from ventral progenitor cells of the pMN domain, characterized by expression of the transcription factor Olig2. A minority of oligodendrocytes is also recognized to emerge from dorsal progenitors during fetal development. The prevailing view is that generation of ventral oligodendrocytes depends on Sonic hedgehog (Shh) while dorsal oligodendrocyte...... hiện toàn bộ
A conserved juxtacrine signal regulates synaptic partner recognition in Caenorhabditis elegansNeural Development - - 2011
Joori Park, Philip Louis Knezevich, William Wung, Shanté Nicole O'Hanlon, Akshi Goyal, Kelli L. Benedetti, Benjamin Barsi‐Rhyne, Mekala R. Raman, Natalyn Mock, Martina Bremer, Miri VanHoven
Abstract
Background
An essential stage of neural development involves the assembly of neural circuits via formation of inter-neuronal connections. Early steps in neural circuit formation, including cell migration, axon guidance, and the localization of synaptic components, are well described. How...... hiện toàn bộ