Neural Development

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Amplification of neural stem cell proliferation by intermediate progenitor cells in Drosophila brain development
Neural Development - Tập 3 - Trang 1-18 - 2008
Bruno C Bello, Natalya Izergina, Emmanuel Caussinus, Heinrich Reichert
In the mammalian brain, neural stem cells divide asymmetrically and often amplify the number of progeny they generate via symmetrically dividing intermediate progenitors. Here we investigate whether specific neural stem cell-like neuroblasts in the brain of Drosophila might also amplify neuronal proliferation by generating symmetrically dividing intermediate progenitors. Cell lineage-tracing and g...... hiện toàn bộ
Meningeal defects alter the tangential migration of cortical interneurons in Foxc1hith/hith mice
Neural Development - - 2012
Konstantinos Zarbalis, Youngshik Choe, Julie A. Siegenthaler, Lori Orosco, Samuel J. Pleasure
Olfactory discrimination largely persists in mice with defects in odorant receptor expression and axon guidance
Neural Development - Tập 7 - Trang 1-14 - 2012
Thomas K Knott, Pasil A Madany, Ashley A Faden, Mei Xu, Jörg Strotmann, Timothy R Henion, Gerald A Schwarting
The defining feature of the main olfactory system in mice is that each olfactory sensory neuron expresses only one of more than a thousand different odorant receptor genes. Axons expressing the same odorant receptor converge onto a small number of targets in the olfactory bulb such that each glomerulus is made up of axon terminals expressing just one odorant receptor. It is thought that this preci...... hiện toàn bộ
In vivo functional analysis of Drosophila Robo1 immunoglobulin-like domains
Neural Development - - 2016
Marie C. Reichert, Haley E. Brown, Tony Evans
Tcf7L2 is essential for neurogenesis in the developing mouse neocortex
Neural Development - Tập 13 - Trang 1-10 - 2018
Olga Chodelkova, Jan Masek, Vladimir Korinek, Zbynek Kozmik, Ondrej Machon
Generation of neurons in the embryonic neocortex is a balanced process of proliferation and differentiation of neuronal progenitor cells. Canonical Wnt signalling is crucial for expansion of radial glial cells in the ventricular zone and for differentiation of intermediate progenitors in the subventricular zone. We detected abundant expression of two transcrtiption factors mediating canonical Wnt ...... hiện toàn bộ
Transcriptional control of axonal guidance and sorting in dorsal interneurons by the Lim-HD proteins Lhx9 and Lhx1
Neural Development - Tập 4 - Trang 1-23 - 2009
Oshri Avraham, Yoav Hadas, Lilach Vald, Sophie Zisman, Adi Schejter, Axel Visel, Avihu Klar
Lim-HD proteins control crucial aspects of neuronal differentiation, including subtype identity and axonal guidance. The Lim-HD proteins Lhx2/9 and Lhx1/5 are expressed in the dorsal spinal interneuron populations dI1 and dI2, respectively. While they are not required for cell fate acquisition, their role in patterning the axonal trajectory of dI1 and dI2 neurons remains incompletely understood. U...... hiện toàn bộ
The Neuroscience Peer Review Consortium
Neural Development - Tập 4 - Trang 1-3 - 2009
Clifford B Saper, John HR Maunsell
As the Neuroscience Peer Review Consortium (NPRC) ends its first year, it is worth looking back to see how the experiment has worked. In order to encourage dissemination of the details outlined in this Editorial, it will also be published in other journals in the Neuroscience Peer Review Consortium.
The BTB/POZ zinc finger protein Broad-Z3 promotes dendritic outgrowth during metamorphic remodeling of the peripheral stretch receptor dbd
Neural Development - Tập 6 - Trang 1-16 - 2011
Janet A Scott, Darren W Williams, James W Truman
Various members of the family of BTB/POZ zinc-finger transcription factors influence patterns of dendritic branching. One such member, Broad, is notable because its BrZ3 isoform is widely expressed in Drosophila in immature neurons around the time of arbor outgrowth. We used the metamorphic remodeling of an identified sensory neuron, the dorsal bipolar dendrite sensory neuron (dbd), to examine the...... hiện toàn bộ
Upregulation of the zebrafish Nogo-A homologue, Rtn4b, in retinal ganglion cells is functionally involved in axon regeneration
Neural Development - - 2015
Cornelia U. Welte, Sarah Engel, Claudia A. O. Stuermer
Midkine-A functions upstream of Id2a to regulate cell cycle kinetics in the developing vertebrate retina
Neural Development - Tập 7 - Trang 1-16 - 2012
Jing Luo, Rosa A Uribe, Sarah Hayton, Anda-Alexandra Calinescu, Jeffrey M Gross, Peter F Hitchcock
Midkine is a small heparin binding growth factor expressed in numerous tissues during development. The unique midkine gene in mammals has two paralogs in zebrafish: midkine-a (mdka) and midkine-b (mdkb). In the zebrafish retina, during both larval development and adult photoreceptor regeneration, mdka is expressed in retinal stem and progenitor cells and functions as a molecular component of the r...... hiện toàn bộ
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