Neonatology
SCIE-ISI SCOPUS (1959-1997,2007-2023)
1661-7800
1661-7819
Thụy Sĩ
Cơ quản chủ quản: S. Karger AG , KARGER
Lĩnh vực:
Developmental BiologyPediatrics, Perinatology and Child Health
Các bài báo tiêu biểu
Can Adverse Neonatal Experiences Alter Brain Development and Subsequent Behavior?Self-destructive behavior in current society promotes a search for psychobiological factors underlying this epidemic. Perinatal brain plasticity increases the vulnerability to early adverse experiences, thus leading to abnormal development and behavior. Although several epidemiological investigations have correlated perinatal and neonatal complications with abnormal adult behavior, our und... ... hiện toàn bộ
Tập 77 Số 2 - Trang 69-82 - 2000
Clinical Importance of Pain and Stress in Preterm NeonatesClinical and laboratory investigations of neonatal pain suggest that preterm neonates have an increased sensitivity to pain and that acute painful stimuli lead to the development of prolonged periods of hyperalgesia. Non-noxious stimuli during these periods of hyperalgesia may expose preterm neonates to established or chronic pain. Acute physiologic changes caused by painful or stressful s... ... hiện toàn bộ
Tập 73 Số 1 - Trang 1-9 - 1998
Development of the Epidermis in the NewbornHistological development of the epidermis was studied on skin samples from 169 infants (gestation 24–40 weeks, age up to 1 year). Gestation markedly influenced epidermal development. Before 30 weeks, the epidermis is thin, has few cell layers and a poorly formed stratum corneum, but by 34 weeks it has largely matured. Postnatal influence on epidermal development is marked in the preterm in... ... hiện toàn bộ
Tập 49 Số 2 - Trang 74-80 - 1986
The Biology of Erythropoietin in the Central Nervous System and Its Neurotrophic and Neuroprotective PotentialThis review summarizes published as well as preliminary data on the biology of erythropoietin (Epo) in the developing and mature human central nervous system (CNS). Both Epo receptor (Epo-R) and Epo gene expression underlie developmental changes and a brain-specific regulation. These features suggest a different role of Epo in normal brain development than in neuroprotection and neuronal t... ... hiện toàn bộ
Tập 79 Số 3-4 - Trang 228-235 - 2001
Hair Cortisol as a Potential Biologic Marker of Chronic Stress in Hospitalized Neonates<i>Background:</i> As preterm and term infants in the neonatal intensive care unit (NICU) undergo multiple stressful/painful procedures, research is required that addresses chronic stress. <i>Objectives:</i> To determine whether (a) hair cortisol levels differed between term and preterm infants exposed to stress in the NICU and (b) an association exists between hair... ... hiện toàn bộ
Tập 92 Số 1 - Trang 42-49 - 2007
Neurodevelopmental Outcome of Extremely Low Birth Weight Infants from the Vermont Oxford Network: 1998–2003<i>Background:</i> Physicians and parents face significant uncertainties when making care decisions for extremely low birth weight (ELBW) infants. Many published estimates of death and developmental outcome are from well-funded university programs and may not reflect outcomes of infants from a variety of settings. The best estimates of the probabilities of death and severe disa... ... hiện toàn bộ
Tập 97 Số 4 - Trang 329-338 - 2010
Inflammatory Mediators and Neonatal Brain DamageInflammatory mediators are multifunctional cytokines that play important roles both in normal central nervous system (CNS) development and in the response of the brain to diverse forms of injury. Interleukin (IL)-1β, tumor necrosis factor-α and IL-6 are among the best-characterized early-response cytokines. Recent data suggest that they may be synthesized and secreted by several CNS cell t... ... hiện toàn bộ
Tập 79 Số 3-4 - Trang 224-227 - 2001
Hypoxia-Ischemia in the Neonatal Rat Brain: Histopathology after Post-Treatment with NMDA and Non NMDA Receptor AntagonistsIn a model of perinatal hypoxic-ischemic brain damage, we examined the neuroprotective efficacy of posttreatment with the NMDA receptor antagonist MK-801 and the AMPA receptor antagonist NBQX. Unilateral brain damage developed in 95% of rat pups subjected to hypoxia-ischemia with a 27.8 ± 1.2% weight deficit of the damaged hemisphere. MK-801 in doses of 0.3 and 0.5 mg/kg i.p. reduced the b... ... hiện toàn bộ
Tập 66 Số 4 - Trang 205-213 - 1994
Erythropoietin Concentrations in Cerebrospinal Fluid of Nonhuman Primates and Fetal Sheep following High-Dose Recombinant ErythropoietinErythropoietin (Epo) decreases neuronal injury and cell death in vitro and in vivo. To lay the groundwork for use of Epo as a potential therapy for brain injury, we tested the hypothesis that systemic dosing of high-dose recombinant Epo (rEpo) would result in neuroprotective rEpo concentrations in the spinal fluid of adult and developing animals. This report characterizes the pharmacokinet... ... hiện toàn bộ
Tập 85 Số 2 - Trang 138-144 - 2004
Tác Động Của Áp Lực Dương Liên Tục Đến Cơ Chế Phổi Và Thể Tích Phổi Ở Trẻ Sơ Sinh Dịch bởi AI Chúng tôi đã nghiên cứu tác động của áp lực dương liên tục (CPAP) đến cơ chế phổi và thể tích khí trong lồng ngực ở 15 lần quan sát trên 12 trẻ sơ sinh khỏe mạnh. Như dự đoán, thể tích khí trong lồng ngực tăng lên và tổng kháng trở phổi giảm. Độ co giãn động giảm xuống trong tất cả các lần quan sát. 43% áp lực được áp dụng đã được truyền qua các cấu trúc trung thất.
Tập 29 Số 3-4 - Trang 178-186 - 1976