Learning and Memory
SCIE-ISI SCOPUS (1994-2023)
1072-0502
1549-5485
Mỹ
Cơ quản chủ quản: Cold Spring Harbor Laboratory Press , COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT
Lĩnh vực:
Neuropsychology and Physiological PsychologyCellular and Molecular NeuroscienceCognitive Neuroscience
Các bài báo tiêu biểu
Context and Behavioral Processes in Extinction: Table 1.This article provides a selective review and integration of the behavioral
literature on Pavlovian extinction. The first part reviews evidence that
extinction does not destroy the original learning, but instead generates new
learning that is especially context-dependent. The second part examines
insights provided by research on several related behavioral phenomena (the
interference paradig... ... hiện toàn bộ
Tập 11 Số 5 - Trang 485-494 - 2004
From Acquisition to Consolidation: On the Role of Brain-Derived Neurotrophic Factor Signaling in Hippocampal-Dependent LearningOne of the most rigorously investigated problems in modern neuroscience is to decipher the mechanisms by which experience-induced changes in the central nervous system are translated into behavioral acquisition, consolidation, retention, and subsequent recall of information. Brain-derived neurotrophic factor (BDNF) has recently emerged as one of the most potent molecular mediators of not o... ... hiện toàn bộ
Tập 9 Số 5 - Trang 224-237 - 2002
Enhanced Human Memory Consolidation With Post-Learning Stress: Interaction With the Degree of Arousal at EncodingAbundant evidence indicates that endogenous stress hormones such as
epinephrine and corticosterone modulate memory consolidation in animals. We
recently provided the first demonstration that an endogenous stress hormone
(epinephrine) can enhance human memory consolidation. However, these findings
also suggested that post-learning stress hormone activation does not uniformly
enhance memory ... ... hiện toàn bộ
Tập 10 Số 4 - Trang 270-274 - 2003
Sex influences on the neurobiology of learning and memoryIn essentially every domain of neuroscience, the generally implicit assumption that few, if any, meaningful differences exist between male and female brain function is being challenged. Here we address how this development is influencing studies of the neurobiology of learning and memory. While it has been commonly held that males show an advantage on spatial tasks, and females on verbal t... ... hiện toàn bộ
Tập 16 Số 4 - Trang 248-266 - 2009
Different Training Procedures Recruit Either One or Two Critical Periods for Contextual Memory Consolidation, Each of Which Requires Protein Synthesis and PKAWe have used a combined genetic and pharmacological approach to define the time course of the requirement for protein kinase A (PKA) and protein synthesis in long-term memory for contextual fear conditioning in mice. The time course of amnesia in transgenic mice that express R(AB) and have genetically reduced PKA activity in the hippocampus parallels that observed both in mice treated with... ... hiện toàn bộ
Tập 5 Số 4 - Trang 365-374 - 1998
Spontaneous RecoverySpontaneous recovery from extinction is one of the most basic phenomena of
Pavlovian conditioning. Although it can be studied by using a variety of
designs, some procedures are better than others for identifying the
involvement of underlying learning processes. A wide range of different
learning mechanisms has been suggested as being engaged by extinction, most of
which have implications f... ... hiện toàn bộ
Tập 11 Số 5 - Trang 501-509 - 2004
Running is the neurogenic and neurotrophic stimulus in environmental enrichmentEnvironmental enrichment (EE) increases dentate gyrus (DG) neurogenesis and brain-derived neurotrophic factor (BDNF) levels. However, running is considered an element of EE. To dissociate effects of physical activity and enrichment on hippocampal neurogenesis and BDNF levels, young female C57Bl/6 mice were housed under control, running, enrichment, or enrichment plus running conditions, an... ... hiện toàn bộ
Tập 18 Số 9 - Trang 605-609 - 2011
Working memory, long-term memory, and medial temporal lobe functionEarly studies of memory-impaired patients with medial temporal lobe (MTL) damage led to the view that the hippocampus and related MTL structures are involved in the formation of long-term memory and that immediate memory and working memory are independent of these structures. This traditional idea has recently been revisited. Impaired performance in patients with MTL lesions on tasks with ... ... hiện toàn bộ
Tập 19 Số 1 - Trang 15-25 - 2012
Environmental Enrichment Modifies the PKA-Dependence of Hippocampal LTP and Improves Hippocampus-Dependent MemorycAMP-dependent protein kinase (PKA) is critical for the expression of some forms of long-term potentiation (LTP) in area CA1 of the mouse hippocampus and for hippocampus-dependent memory. Exposure to spatially enriched environments can modify LTP and improve behavioral memory in rodents, but the molecular bases for the enhanced memory performance seen in enriched animals are undefined. We ... ... hiện toàn bộ
Tập 8 Số 1 - Trang 26-34 - 2001
Different mechanisms of fear extinction dependent on length of time since fear acquisitionFear extinction is defined as a decline in conditioned fear responses (CRs) following nonreinforced exposure to a feared conditioned stimulus (CS). Behavioral evidence indicates that extinction is a form of inhibitory learning: Extinguished fear responses reappear with the passage of time (spontaneous recovery), a shift of context (renewal), and unsignaled presentations of the unconditione... ... hiện toàn bộ
Tập 13 Số 2 - Trang 216-223 - 2006