Working memory, long-term memory, and medial temporal lobe function
Tóm tắt
Early studies of memory-impaired patients with medial temporal lobe (MTL) damage led to the view that the hippocampus and related MTL structures are involved in the formation of long-term memory and that immediate memory and working memory are independent of these structures. This traditional idea has recently been revisited. Impaired performance in patients with MTL lesions on tasks with short retention intervals, or no retention interval, and neuroimaging findings with similar tasks have been interpreted to mean that the MTL is sometimes needed for working memory and possibly even for visual perception itself. We present a reappraisal of this interpretation. Our main conclusion is that, if the material to be learned exceeds working memory capacity, if the material is difficult to rehearse, or if attention is diverted, performance depends on long-term memory even when the retention interval is brief. This fundamental notion is better captured by the terms subspan memory and supraspan memory than by the terms short-term memory and long-term memory. We propose methods for determining when performance on short-delay tasks must depend on long-term (supraspan) memory and suggest that MTL lesions impair performance only when immediate memory and working memory are insufficient to support performance. In neuroimaging studies, MTL activity during encoding is influenced by the memory load and correlates positively with long-term retention of the material that was presented. The most parsimonious and consistent interpretation of all the data is that subspan memoranda are supported by immediate memory and working memory and are independent of the MTL.
Từ khóa
Tài liệu tham khảo
1992, The performance of postencephalitic amnesic subjects on two behavioural tests of memory: Concurrent discrimination learning and delayed matching-to-sample, Cortex, 28, 359, 10.1016/S0010-9452(13)80146-3
Atkinson RC , Shiffrin RM . 1968. Human memory: A proposed system and its control processes. In The psychology of learning and motivation: II (ed. Spence KW , Spence JT ). Academic Press, Oxford, England.
Baddeley AD , Hitch GJ . 1974. Working memory. In The psychology of learning and motivation: Advances in research and theory (ed. Bower GH ), pp. 47–89. Academic, New York.
Bergmann HC , Rijpkema M , Fernández G , Kessels RPC . 2010. Neural substrates of working memory and long-term memory. Program no. 603.15/KKK59, 2010 Neuroscience Meeting Planner. Society for Neuroscience, San Diego, CA.
2005, Visual working memory for simple and complex visual stimuli, Psychon Bull Rev, 12, 1127, 10.3758/BF03206454
1982, Neuronal firing in the inferotemporal cortex of the monkey in a visual memory task, J Neurosci, 2, 361, 10.1523/JNEUROSCI.02-03-00361.1982
2000, Perceptual and mnemonic matching-to-sample in humans: Contributions of the hippocampus, perirhinal, and other medial temporal lobe cortices, Cortex, 36, 301, 10.1016/S0010-9452(08)70843-8
Jeneson A , Wixted JT , Hopkins RO , Squire LR . 2011a. Intact visual working memory capacity after medial temporal lobe damage. Cognitive Neuroscience 18th Annual Meeting, San Francisco, CA.
1972, Disorders of learning and memory after temporal lobe lesions in man, Clin Neur, 19, 421, 10.1093/neurosurgery/19.CN_suppl_1.421
2009, Performance-related sustained and anticipatory activity in human medial temporal lobe during delayed match-to-sample, J Neurosci, 23, 11880
1990, Picture recognition vs. picture discrimination learning in monkeys with medial temporal removals, Exp Brain Res, 79, 18
Schon K , Newmark RE , Ross RS , Quiroz YT , Stern CE . 2010. Working memory load effects in hippocampal subfields: A high-resolution fMRI study. Program no. 398.14/KKK40, 2010 Neuroscience Meeting Planner. Society for Neuroscience, San Diego, CA.
2003, Making memories without trying: Medial temporal lobe activity associated with incidental memory formation during recognition, J Neurosci, 23, 6748, 10.1523/JNEUROSCI.23-17-06748.2003
2009, Perception and the medial temporal lobe: Evaluating the current evidence, Neuron, 6, 657
2004, Neural activity predicts individual differences in visual working memory capacity, Nature, 15, 748