Lasers in Surgery and Medicine
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Photodynamic therapy in the treatment of microbial infections: Basic principles and perspective applications
Lasers in Surgery and Medicine - Tập 38 Số 5 - Trang 468-481 - 2006
AbstractBackground and ObjectivesPhotodynamic therapy (PDT) appears to be
endowed with several favorable features for the treatment of infections
originated by microbial pathogens, including a broad spectrum of action, the
efficient inactivation of antibiotic‐resistant strains, the low mutagenic
potential, and the lack of selection of photoresistant microbial cells.
Therefore, intensive studies ar...
Initiation of apoptosis and autophagy by photodynamic therapy
Lasers in Surgery and Medicine - Tập 38 Số 5 - Trang 482-488 - 2006
AbstractBackground and ObjectivesThis study was designed to examine modes of
cell death after photodynamic therapy (PDT).Study DesignMurine leukemia L1210
cells and human prostate Bax‐deficient DU145 cells were examined after
PDT‐induced photodamage to the endoplasmic reticulum (ER). Phase contrast,
fluorescence and electron microscopy were used to identify changes in cellular
morphology, chromati...
Cultured epithelial cells response to phototherapy with low intensity laser
Lasers in Surgery and Medicine - Tập 39 Số 4 - Trang 365-372 - 2007
AbstractBackground and ObjectivesLittle is known about the intracellular
response of epithelial cells to phototherapy. The aim of this in vitro study was
to analyze the effect of phototherapy with low‐energy lasers with different
wavelengths and powers on cultured epithelial cell growth under different
nutritional conditions.Study Design/Materials and MethodsEpithelial cell
cultures (Vero cell lin...
Treatment of experimentally induced transient cerebral ischemia with low energy laser inhibits nitric oxide synthase activity and up‐regulates the expression of transforming growth factor‐beta 1
Lasers in Surgery and Medicine - Tập 31 Số 4 - Trang 283-288 - 2002
AbstractBackground and ObjectivesNitric oxide (NO) has been shown to be
neurotoxic while transforming growth factor‐beta 1 (TGF‐β1) is neuroprotective
in the stroke model. The present study investigates the effects of low energy
laser on nitric oxide synthase (NOS) and TGF‐β1 activities after cerebral
ischemia and reperfusion injury.Study Design/Materials and MethodsCerebral
ischemia was induced f...
In vivo effects of low level laser therapy on inducible nitric oxide synthase
Lasers in Surgery and Medicine - Tập 41 Số 3 - Trang 227-231 - 2009
AbstractBackground and ObjectiveLow level laser therapy (LLLT) has been
demonstrated to modulate inflammatory processes with evidence suggesting that
treatment protocol, such as wavelength, total energy, and number of treatments
determine the clinical efficacy. In this study, the effects of LLLT mediated by
different wavelengths and continuous versus pulsed delivery mode were quantified
in a trans...
Stem cell proliferation under low intensity laser irradiation: A preliminary study
Lasers in Surgery and Medicine - Tập 40 Số 6 - Trang 433-438 - 2008
AbstractBackground and ObjectivesPhototherapy with low intensity laser
irradiation has shown to be effective in promoting the proliferation of
different cells. The aim of this in vitro study was to evaluate the potential
effect of laser phototherapy (660 nm) on human dental pulp stem cell (hDPSC)
proliferation.Study Design/Materials and MethodsThe hDPSC cell strain was used.
Cells cultured under n...
Irradiation at 780 nm increases proliferation rate of osteoblasts independently of dexamethasone presence
Lasers in Surgery and Medicine - Tập 38 Số 4 - Trang 332-336 - 2006
Transcranial application of low‐energy laser irradiation improves neurological deficits in rats following acute stroke
Lasers in Surgery and Medicine - Tập 38 Số 1 - Trang 70-73 - 2006
AbstractBackground and ObjectivesLow‐level laser therapy (LLLT) has been shown
to have beneficial effects on ischemic skeletal and heart muscles tissues. The
aim of the present study was to approve the effectiveness of LLLT treatment at
different locations on the brain in acute stroked rats.Study Design/Materials
and MethodsStroke was induced in 169 rats that were divided into four groups:
control...
Modulations of VEGF and iNOS in the rat heart by low level laser therapy are associated with cardioprotection and enhanced angiogenesis
Lasers in Surgery and Medicine - Tập 38 Số 7 - Trang 682-688 - 2006
AbstractBackground and ObjectivesIt has been shown previously that low‐level
laser therapy (LLLT) significantly reduces infarct size following induction of
myocardial infarction in rats and dogs. The aim of the present study was to
investigate the effect of LLLT on the expression of vascular endothelial growth
factor (VEGF) and inducible nitric oxide synthase (iNOS).Study Design and
Material and M...
Anti‐Inflammatory effects of low‐level laser therapy (660 nm) in the early phase in carrageenan‐induced pleurisy in rat
Lasers in Surgery and Medicine - Tập 40 Số 7 - Trang 500-508 - 2008
AbstractBackground and ObjectiveIn the classic model of pleurisy there is little
evidence about the anti‐inflammatory effects of low‐level laser therapy (LLLT)
as well the dosage characteristics, such as wavelength, total energy, number and
pattern of treatment. In this study we investigated the potential effects of
LLLT on modulating the pro‐inflammatory and anti‐inflammatory mediators of acute
i...
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