Journal of Pharmacy and Pharmacology
SCOPUS (1949-2023)SCIE-ISI
0022-3573
Cơ quản chủ quản: OXFORD UNIV PRESS , Oxford University Press
Lĩnh vực:
PharmacologyPharmaceutical Science
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Nanoparticle Uptake by the Rat Gastrointestinal Mucosa: Quantitation and Particle Size DependencyAbstract
Polystyrene microspheres in the size range 50 nm to 3 μm were fed by gavage to female Sprague Dawley rats daily for 10 days at a dose of 1.25 mg kg−1. Previous histological evidence of the uptake of these particles and their absorption across the gastrointestinal tract and passage via the mesentery lymph supply and lymph nodes to the liver a... ... hiện toàn bộ
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Nanosuspensions: a promising drug delivery strategyAbstract
Nanosuspensions have emerged as a promising strategy for the efficient delivery of hydrophobic drugs because of their versatile features and unique advantages. Techniques such as media milling and high-pressure homogenization have been used commercially for producing nanosuspensions. Recently, the engineering of nanosuspensions employing emu... ... hiện toàn bộ
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St John's wort (Hypericum perforatum L.): a review of its chemistry, pharmacology and clinical propertiesAbstract
The chemical composition of St. John's wort has been well-studied. Documented pharmacological activities, including antidepressant, antiviral, and antibacterial effects, provide supporting evidence for several of the traditional uses stated for St John's wort. Many pharmacological activities appear to be attributable to hypericin and to the ... ... hiện toàn bộ
Tập 53 Số 5 - Trang 583-600 - 2010
Pharmacology of diferuloyl methane (curcumin), a non-steroidal anti-inflammatory agentAbstract
Some pharmacological actions of curcumin (diferuloyl methane) have been examined in rats, mice and cats. The compound possesses significant anti-inflammatory activity in acute as well as in chronic models of inflammation. It is as potent as phenylbutazone in the carrageenan oedema test but only half as potent in chronic tests. Curcumin posse... ... hiện toàn bộ
Tập 25 Số 6 - Trang 447-452 - 2011
Drug-delivery Products and the Zydis Fast-dissolving Dosage FormAbstract
Many patients find it difficult to swallow tablets and hard gelatin capsules and do not take their medication as prescribed. It is estimated that 50% of the population is affected by this problem which results in a high incidence of non-compliance and ineffective therapy. The difficulty is experienced in particular by paediatric and geriatri... ... hiện toàn bộ
Tập 50 Số 4 - Trang 375-382 - 2011
A Survey of the Antibacterial Activity of Some New Zealand HoneysAbstract
To assess the variation in antibacterial activity of honey a survey was carried out on 345 samples of unpasteurized honey obtained from commercial apiarists throughout New Zealand. Most of the honeys were considered to be monofloral, from 26 different floral sources. The honeys were tested against Staphylococcus aureus in an agar well diffus... ... hiện toàn bộ
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Stimulation of locomotor activity following injection of dopamine into the nucleus accumbens
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An in-vitro investigation of mucosa-adhesive materials for use in controlled drug deliveryAbstract
An in-vitro test system was developed to investigate the adhesiveness of various materials to mucus. The results obtained showed good agreement with the findings of previous in-vivo evaluations of mucosa-adhesives. Further investigations found that these materials become adhesive on hydration. Chain length, and the presence of ionizable grou... ... hiện toàn bộ
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