Anti-inflammatory Effects of South American Tanacetum vulgareJournal of Pharmacy and Pharmacology - Tập 50 Số 9 - Trang 1069-1074 - 1998
Guillermo Schinella, Rosa M. Giner, Marı́a del Carmen Recio, Perla M. de Buschiazzo, José-Luis Rı́os, Salvador Máñez
Abstract
In recent years the role of phenolic compounds and sesquiterpene lactones, particularly parthenolide, in the anti-migraine and anti-inflammatory effects of Tanacetum parthenium (Asteraceae) has attracted much attention. However, the closely-related cosmopolitan species T. vulgare has remained outside the mainstream of research in this field....... hiện toàn bộ
Drug repositioning: a brief overviewJournal of Pharmacy and Pharmacology - Tập 72 Số 9 - Trang 1145-1151 - 2020
Jean‐Pierre Jourdan, Ronan Bureau, Christophe Rochais, Patrick Dallemagne
Abstract
Objectives
Drug repositioning, that is, the use of a drug in an indication other than the one for which it was initially marketed, is a growing trend. Its origins lie mainly in the attrition experienced in recent years in the field of new drug discovery.
...... hiện toàn bộ
The anti-arthritic effect of ursolic acid on zymosan-induced acute inflammation and adjuvant-induced chronic arthritis modelsJournal of Pharmacy and Pharmacology - Tập 60 Số 10 - Trang 1347-1354 - 2010
Suk-Yun Kang, Seo‐Yeon Yoon, Dae‐Hyun Roh, Mi‐Jeong Jeon, Hyoung‐Sig Seo, Dong-Kyu Uh, Young‐Bae Kwon, Hyun‐Woo Kim, Ho Jae Han, Hye‐Jung Lee, Jang‐Hern Lee
Abstract
Ursolic acid (UA) is pentacyclic triterpenoic acid that naturally occurs in many medicinal herbs and plants. In this study, we examined the possible suppressive effect of UA extracted from Oldenlandia diffusa on zymosan-induced acute inflammation in mice and complete Freund's adjuvant (CFA)-induced arthritis in rats. UA treatment (per oral) ...... hiện toàn bộ