Journal of Pharmacy and Pharmacology

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The genus Cratoxylum: traditional use, phytochemistry and pharmacology
Journal of Pharmacy and Pharmacology - Tập 75 Số 10 - Trang 1259-1293 - 2023
Huong, Nguyen Thi, Hop, Nguyen Quang, Son, Ninh The
Synthesis and in-vitro anticancer evaluation of bistacrine congeners
Journal of Pharmacy and Pharmacology - Tập 53 Số 1 - Trang 83-88 - 2010
Ming‐Kuan Hu
Abstract In the search for potential new anticancer drugs, an efficient synthesis of bis-tetrahydroaminoacridine (bis-tacrine) and its congeners was accomplished by bis-amination of 9-chlorotetrahydroacridine and its congeners under heated conditions. The critical chlorides were efficiently prepared from o-aminoaromati...... hiện toàn bộ
Generation and characterization of soluble interleukin-33 receptor fused with immunoglobulin gamma-1 constant domain expressed by Pichia pastoris yeast
Journal of Pharmacy and Pharmacology - Tập 67 Số 3 - Trang 329-337 - 2015
Nguyen, Thi Thanh Thao, Truong, Thi Hoang Dieu, Le, Gia Bao, Duong, Hoa Xo, Nguyen, Quoc Binh, Nguyen, Dang Quan
Effect of tranilast on matrix metalloproteinase production from neutrophils in-vitro
Journal of Pharmacy and Pharmacology - Tập 58 Số 1 - Trang 91-99 - 2010
Toshiyuki Shimizu, Kenichi Kanai, Yoshiyuki Kyo, Harumi Suzaki, Kazuhito Asano, Tadashi Hisamitsu
AbstractTranilast is an anti-allergic agent that blocks the release of chemical mediators, such as histamine and leukotrienes from mast cells, and has been reported to suppress keloid and hypertrophic scar formation. Since matrix metalloproteinases (MMPs) play an essential role in tissue remodelling, this study was undertaken to determine whether tranilast suppress...... hiện toàn bộ
Natural products as targeted modulators of the nuclear factor-κB pathway
Journal of Pharmacy and Pharmacology - Tập 54 Số 4 - Trang 453-472 - 2002
Paul Bremner, Michael Heinrich
Abstract The use of plant extracts to alleviate inflammatory diseases is centuries old and continues to this day. This review assesses the current understanding of the use of such plants and natural products isolated from them in terms of their action against the ubiquitous transcription factor, nuclear factor kappa B (NF-κB). As an activator of many...... hiện toàn bộ
Novel oral fast-disintegrating drug delivery devices with predefined inner structure fabricated by Three-Dimensional Printing
Journal of Pharmacy and Pharmacology - Tập 61 Số 3 - Trang 323-329 - 2009
Deng‐Guang Yu, Xia‐Xia Shen, C. Branford-White, Li‐Min Zhu, Kenneth White, Xiangliang Yang
Abstract Objectives Novel fast-disintegrating drug delivery devices with special inner structure characteristics were designed and fabricated using Three-Dimensional Printing. Methods... hiện toàn bộ
Application of the Ferguson principle to the antibacterial activity of mono- and multi-component solutions of quaternary ammonium surface-active agents
Journal of Pharmacy and Pharmacology - Tập 22 Số Supplement_1 - Trang 157S-162S - 1970
H H Laycock, B A Mulley
Abstract Critical micelle concentrations (cmc) have been measured by the surface tension method for binary mixtures of dodecyltrimethyl-ammonium bromide with tetradecyltrimethylammonium bromide, binary mixtures of C14/C16 homologues, a ternary mixture of the C12/C14/C16 compounds and additionally for each component individually. The antibacterial act...... hiện toàn bộ
Surface Characterization: Understanding Sources of Variability in the Production and Use of Pharmaceuticals
Journal of Pharmacy and Pharmacology - Tập 47 Số 4 - Trang 265-275 - 1995
Graham Buckton
Effects of an Essential Oil from the Bark of Croton cajucara Benth. on Experimental Gastric Ulcer Models in Rats and Mice
Journal of Pharmacy and Pharmacology - Tập 51 Số 3 - Trang 341-346 - 1999
Clélia Akiko Hiruma-Lima, J.S. Gracioso, Domingos Sávio Nunes, Arm Souza Brito
Abstract Croton cajucara Benth. (Euphorbiaceae) is widely used in Amazonian folk medicine for the treatment of a wide range of gastrointestinal symptoms. The essential oil from its bark was investigated for acute toxicity in mice and for its ability to prevent the formation of ulceration of the gastric mucosa in different models of experimentally ind...... hiện toàn bộ
Effects of a Polysaccharide Fraction from the Roots of Bupleurum falcatum L. on Experimental Gastric Ulcer Models in Rats and Mice
Journal of Pharmacy and Pharmacology - Tập 43 Số 10 - Trang 699-704 - 1991
X.‐B. Sun, T Matsumoto, Haruki Yamada
Abstract Effects of an acidic polysaccharide fraction, BR-2, from the roots of Bupleurum falcatum L., on HCl-ethanol, ethanol and water immersion stress-induced gastric lesions in mice and pylorus-ligated ulcers in rats have been studied. Oral administration of BR-2 at doses of 50 to 200 mg kg−1 inhibited the formation of the gastric lesions induced ...... hiện toàn bộ
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