Journal of Molecular Psychiatry

  2049-9256

 

 

 

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Association study in siblings and case-controls of serotonin- and oxytocin-related genes with high functioning autism
- 2014
Johanna Nyffeler, Susanne Walitza, Elise Bobrowski, Ronnie Gundelfinger, Edna Grünblatt
Journal of Molecular Psychiatry
- 2013
Johannes Thome
Genetics and epigenetics of alcohol dependence
Tập 1 - Trang 1-6 - 2013
Vanessa Nieratschker, Anil Batra, Andreas J Fallgatter
Alcohol dependence is a severe and common disorder associated with high morbidity and mortality rates. Genetic as well as environmental factors are known to modulate susceptibility to alcohol dependence. There is a growing body of evidence suggesting that this interaction between the genome and the environment is mediated by epigenetic mechanisms, e.g. DNA methylation at CpG sites. Following an in...... hiện toàn bộ
The neurobiology of suicide - A Review of post-mortem studies
Tập 1 - Trang 1-22 - 2013
Karolina Furczyk, Barbora Schutová, Tanja M Michel, Johannes Thome, Andreas Büttner
The neurobiology of suicidal behaviour, which constitutes one of the most serious problems both in psychiatry and general medical practice, still remains to a large degree unclear. As a result, scientists constantly look for new opportunities of explaining the causes underlying suicidality. In order to elucidate the biological changes occurring in the brains of the suicide victims, studies based o...... hiện toàn bộ
NRXN1 deletions identified by array comparative genome hybridisation in a clinical case series – further understanding of the relevance of NRXN1 to neurodevelopmental disorders
Tập 1 - Trang 1-7 - 2013
Sarah Curran, Joo Wook Ahn, Hannah Grayton, David A Collier, Caroline Mackie Ogilvie
Microdeletions in the NRXN1 gene have been associated with a range of neurodevelopmental disorders, including autism spectrum disorders, schizophrenia, intellectual disability, speech and language delay, epilepsy and hypotonia. In the present study we performed array CGH analysis on 10,397 individuals referred for diagnostic cytogenetic analysis, using a custom oligonucleotide array, which include...... hiện toàn bộ
Centenary of Karl Jaspers’s general psychopathology: implications for molecular psychiatry
Tập 2 - Trang 1-5 - 2014
Johannes Thome
Modern molecular psychiatry benefits immensely from the scientific and technological advances of general neuroscience (including genetics, epigenetics, and proteomics). This “progress” of molecular psychiatry, however, will be to a degree “unbalanced” and “epiphytic” should the development of the corresponding theoretical frameworks and conceptualization tools that allow contextualization of the i...... hiện toàn bộ
Neuroregeneration and dementia: new treatment options
Tập 1 - Trang 1-6 - 2013
Smaranda Ioana Mitran, Bogdan Catalin, Veronica Sfredel, Tudor-Adrian Balseanu
In the last years, physiological aging became a general concept that includes all the changes that occur in organism with old age. It is obvious now, that in developing and developed countries, new health problems concerning older population appear. One of these major concerns is probably dementia. Sooner or later, all forms of dementia lead to learning deficit, memory loss, low attention span, im...... hiện toàn bộ
Methylphenidate enhances neural stem cell differentiation
Tập 1 - Trang 1-5 - 2013
Jasmin Bartl, Takatoshi Mori, Peter Riederer, Hiroki Ozawa, Edna Grünblatt
The psychostimulant methylphenidate (MPH) is the first choice of drug treatment in Attention-Deficit/Hyperactivity Disorder (ADHD). Since therapy often begins at a time when the brain is still developing and the long-term consequences of MPH are still not fully clarified, we examined the influences of an acute treatment with MPH on the differentiation and proliferation of murine neural stem cells ...... hiện toàn bộ
Erratum to: Methylphenidate enhances neural stem cell differentiation
Tập 1 - Trang 1-2 - 2013
Jasmin Bartl, Takatoshi Mori, Peter Riederer, Hiroki Ozawa, Edna Grünblatt