Journal of Molecular Psychiatry
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2049-9256
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Centenary of Karl Jaspers’s general psychopathology: implications for molecular psychiatry
Tập 2 - Trang 1-5 - 2014
Modern molecular psychiatry benefits immensely from the scientific and
technological advances of general neuroscience (including genetics, epigenetics,
and proteomics). This “progress” of molecular psychiatry, however, will be to a
degree “unbalanced” and “epiphytic” should the development of the corresponding
theoretical frameworks and conceptualization tools that allow contextualization
of the i...
The neurobiology of suicide - A Review of post-mortem studies
Tập 1 - Trang 1-22 - 2013
The neurobiology of suicidal behaviour, which constitutes one of the most
serious problems both in psychiatry and general medical practice, still remains
to a large degree unclear. As a result, scientists constantly look for new
opportunities of explaining the causes underlying suicidality. In order to
elucidate the biological changes occurring in the brains of the suicide victims,
studies based o...
Post-stroke depression and the aging brain
Tập 1 - Trang 1-10 - 2013
Ageing is associated with changes in the function of various organ systems.
Changes in the cardiovascular system affect both directly and indirectly the
function in a variety of organs, including the brain, with consequent
neurological (motor and sensory performance) and cognitive impairments, as well
as leading to the development of various psychiatric diseases. Post-stroke
depression (PSD) is am...
The amygdala between sensation and affect: a role in pain
Tập 1 - Trang 1-14 - 2013
The amygdala is a structure of the temporal lobe thought to be involved in
assigning emotional significance to environmental information and triggering
adapted physiological, behavioral and affective responses. A large body of
literature in animals and human implicates the amygdala in fear. Pain having a
strong affective and emotional dimension, the amygdala, especially its central
nucleus (CeA), ...
Genetics and epigenetics of alcohol dependence
Tập 1 - Trang 1-6 - 2013
Alcohol dependence is a severe and common disorder associated with high
morbidity and mortality rates. Genetic as well as environmental factors are
known to modulate susceptibility to alcohol dependence. There is a growing body
of evidence suggesting that this interaction between the genome and the
environment is mediated by epigenetic mechanisms, e.g. DNA methylation at CpG
sites. Following an in...