The amygdala is a structure of the temporal lobe thought to be involved in
assigning emotional significance to environmental information and triggering
adapted physiological, behavioral and affective responses. A large body of
literature in animals and human implicates the amygdala in fear. Pain having a
strong affective and emotional dimension, the amygdala, especially its central
nucleus (CeA), ... hiện toàn bộ
Vanessa Nieratschker, Anil Batra, Andreas J Fallgatter
Alcohol dependence is a severe and common disorder associated with high
morbidity and mortality rates. Genetic as well as environmental factors are
known to modulate susceptibility to alcohol dependence. There is a growing body
of evidence suggesting that this interaction between the genome and the
environment is mediated by epigenetic mechanisms, e.g. DNA methylation at CpG
sites. Following an in... hiện toàn bộ
In the last years, physiological aging became a general concept that includes
all the changes that occur in organism with old age. It is obvious now, that in
developing and developed countries, new health problems concerning older
population appear. One of these major concerns is probably dementia. Sooner or
later, all forms of dementia lead to learning deficit, memory loss, low
attention span, im... hiện toàn bộ
Aurel Popa-Wagner, Karolina Furczyk, Joerg Richter, Gisela Irmisch, Johannes Thome
The neurotrophins brain-derived neurotrophic factor (BDNF) and neurotrophic
factor 3 (NT3) could play a role in addictive behavior. Interactions between
BDNF and dopamine transmission influence the alcohol intake. It has been
hypothesized that extensive alcohol consumption leads to diminished circulating
BDNF levels and impaired BDNF-mediated protective mechanisms. What is more,
alcohol dependency... hiện toàn bộ
Karolina Furczyk, Barbora Schutová, Tanja M Michel, Johannes Thome, Andreas Büttner
The neurobiology of suicidal behaviour, which constitutes one of the most
serious problems both in psychiatry and general medical practice, still remains
to a large degree unclear. As a result, scientists constantly look for new
opportunities of explaining the causes underlying suicidality. In order to
elucidate the biological changes occurring in the brains of the suicide victims,
studies based o... hiện toàn bộ
Gabriel R Cojocaru, Aurel Popa-Wagner, Elena C Stanciulescu, Loredana Babadan, Ana-Maria Buga
Ageing is associated with changes in the function of various organ systems.
Changes in the cardiovascular system affect both directly and indirectly the
function in a variety of organs, including the brain, with consequent
neurological (motor and sensory performance) and cognitive impairments, as well
as leading to the development of various psychiatric diseases. Post-stroke
depression (PSD) is am... hiện toàn bộ