Journal of Gastroenterology and Hepatology (Australia)
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Altered phenotype of dextran sulfate sodium colitis in interferon regulatory factor‐1 knock‐out miceAbstract Background and Aims: Interferon regulatory factor‐1 (IRF‐1) is a transcription factor with antiviral, proinflammatory and tumor suppressor properties. We examined the role of IRF‐1 in dextran sulfate sodium colitis, a murine model of inflammatory bowel disease, to determine if absence of the gene would protect against colitis....
Journal of Gastroenterology and Hepatology (Australia) - Tập 20 Số 3 - Trang 371-380 - 2005
Clinical usefulness of subgrouping of patients with non‐cardiac chest pain according to characteristic symptoms in KoreaAbstract Background: Non‐cardiac chest pain (NCCP) is a heterogeneous disorder. There is controversy about the associations between symptoms and causes in NCCP patients. The purpose of the present study was to evaluate the clinical usefulness of subgrouping according to characteristic symptoms in NCCP patients.Pati...
Journal of Gastroenterology and Hepatology (Australia) - Tập 22 Số 3 - Trang 320-325 - 2007
Cystic fibrosis: An update for clinicians. Part 1: Nutrition and gastrointestinal complicationsAbstract During three decades, the demographics of cystic fibrosis (CF ) has undergone a significant change. Advances in nutritional and pulmonary management allow the vast majority of patients reaching adulthood today. With increasing survival, new and previously less common aspects of ...
Journal of Gastroenterology and Hepatology (Australia) - Tập 29 Số 7 - Trang 1344-1355 - 2014
Des‐γ‐carboxyprothrombin, α‐fetoprotein and AFP‐L3 in patients with chronic hepatitis, cirrhosis and hepatocellular carcinomaAbstract Background and Aim: Hepatocellular carcinoma (HCC) is a common complication in patients with chronic viral hepatitis. Detection of HCC at an early stage is critical for a favorable clinical outcome. The study aim was to: (i) compare the levels of des‐γ‐carboxyprothrombin (DCP), α‐fetoprotein (AFP) and AFP‐L3 in HCC patients and in ch...
Journal of Gastroenterology and Hepatology (Australia) - Tập 23 Số 10 - Trang 1541-1548 - 2008
Expression of the caudal‐type homeodomain transcription factor CDX2 is related to clinical outcome in biliary tract carcinomaAbstract Background and Aim: The caudal‐type homeodomain transcriptional factor CDX2, a member of the caudal‐related homeobox gene family, plays a crucial role in the regulation of cell proliferation and differentiation in the gut. Recent studies have reported that expression of CDX2 was an independent marker of outcome in patients with resec...
Journal of Gastroenterology and Hepatology (Australia) - Tập 22 Số 3 - Trang 389-394 - 2007
Diabetes is an independent risk factor for peptic ulcer bleeding: A nationwide population‐based cohort studyAbstract Background and Aims Diabetic patients reportedly have a higher incidence of peptic ulcer disease. The aim of this study was to investigate if type II diabetic patients have higher risk of developing peptic ulcer bleeding (P...
Journal of Gastroenterology and Hepatology (Australia) - Tập 28 Số 8 - Trang 1295-1299 - 2013
Nonalcoholic fatty liver disease is associated with an almost twofold increased risk of incident type 2 diabetes and metabolic syndrome. Evidence from a systematic review and meta‐analysisAbstract Background and Aim: The magnitude of the risk of incident type 2 diabetes (T2D) and metabolic syndrome (MetS) among patients with nonalcoholic fatty liver disease (NAFLD) is poorly known. We gauged the risk of developing T2D and MetS in patients with NAFLD diagnosed by either serum liver enzymes (aminotransferases or gamma‐...
Journal of Gastroenterology and Hepatology (Australia) - Tập 31 Số 5 - Trang 936-944 - 2016
Clinical association between non‐alcoholic fatty liver disease and the development of hypertensionAbstract Background and Aim Non‐alcoholic fatty liver disease (NAFLD ) is getting an increasing attention for its clinical implications on cardiovascular disease (CVD ). However, epidemiologic data are not so evi...
Journal of Gastroenterology and Hepatology (Australia) - Tập 29 Số 11 - Trang 1926-1931 - 2014
Visceral adipose tissue area is an independent risk factor for hepatic steatosisAbstract Background and Aim: Recent data indicate that hepatic steatosis is associated with insulin resistance, dyslipidemia and obesity (especially central body fat distribution). There have been few studies on the correlation between biopsy‐proven hepatic steatosis and the above factors in a disease‐free population. The aim of the present st...
Journal of Gastroenterology and Hepatology (Australia) - Tập 23 Số 6 - Trang 900-907 - 2008
Predicting mortality in patients with cirrhosis of liver with application of neural network technologyAbstract Background: Prediction of mortality from cirrhosis is important in planning optimal timing of liver transplantation and other interventions. We evaluated the role of the Artificial Neural Network (ANN), which uses non‐linear statistics for pattern recognition in predicting one‐year liver disease‐related mortality using information av...
Journal of Gastroenterology and Hepatology (Australia) - Tập 18 Số 9 - Trang 1054-1060 - 2003
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