Journal of Experimental Orthopaedics

  2197-1153

 

 

Cơ quản chủ quản:  Springer Berlin , Springer Nature

Lĩnh vực:
Orthopedics and Sports Medicine

Các bài báo tiêu biểu

COVID-19 - ESSKA guidelines and recommendations for resuming elective surgery
- 2020
Caroline Mouton, Michael T. Hirschmann, Matthieu Ollivier, Romain Seil, Jacques Ménétrey
Abstract

The roadmap to elective surgery resumption after this COVID-19 pandemic should be progressive and cautious. The aim of this paper was to give recommendations and guidelines for resuming elective orthopedic surgery in the safest environment possible. Elective surgery should be performed in COVID-free facilities and hospital stay should be as short as possible. For matters of safety, patients considered first for surgery should be carefully selected according to COVID infection status/exposure, age, ASA physical status classification system / risk factors, socio-professional situation and surgical indication. A strategy for resuming elective surgery in four phases is proposed. Preoperative testing for COVID-19 infection is highly recommended. In any cases, COVID symptoms including fever and increased temperature should be constantly monitored until the day of surgery. Elective surgery should be postponed at the slightest suspicion of a COVID-19 infection. In case of surgery, adapted personal protective equipment in terms of gowns, gloves, masks and eye protection is highly recommended and described.

Digital image correlation as a tool for three-dimensional strain analysis in human tendon tissue
Tập 1 Số 1 - 2014
Thomas Luyckx, Matthias Verstraete, Karel De Roo, Wim De Waele, Johan Bellemans, Jan Victor
Autologous micro-fragmented adipose tissue for the treatment of diffuse degenerative knee osteoarthritis: an update at 3 year follow-up
Tập 5 Số 1 - 2018
Arcangelo Russo, Daniele Screpis, Sigismondo Luca Di Donato, Stefano Bonetti, Gianluca Piovan, Claudio Zorzi
The role of meniscal repair for prevention of early onset of osteoarthritis
- 2018
Johannes Weber, Matthias Koch, Peter Angele, Johannes Zellner
Biomechanical properties of five different currently used implants for open-wedge high tibial osteotomy
- 2015
Arnaud Diffo Kaze, Stefan Maas, Danièle Waldmann, Andreas Zilian, Klaus Dueck, Dietrich Pape
Computer and robotic – assisted total knee arthroplasty: a review of outcomes
- 2020
Jobe Shatrov, David Parker
Abstract Background

Total knee arthroplasty (TKA) is a successful treatment for tricompartmental knee arthritis. Computer navigation and robotic-assisted-surgery (RAS) have emerged as tools that aim to help plan and execute surgery with greater precision and consistency. We reviewed the most current literature to describe the historical background and outcomes compared to conventional TKA.

Methods

A review and synthesis of the literature comparing the patient reported outcomes (PROM’s) of RA TKA and computer-assisted (CA) TKA to conventional TKA was performed using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.

Results

CAS TKA improves accuracy and consistency of implant position, and appears to provide a small improvement in PROMs and implant survival compared to conventional TKA. RTKA similarly improves implant accuracy compared to conventional techniques and early results suggest a similar small benefit in PROMs compared to conventional TKA. A strengthening trend is emerging showing CAS TKA has greatest benefit to implant survival in people under 65. RTKA survival analysis data is more limited and early results do not allow strong conclusions, however early trends are similar to CAS TKA.

Conclusion

Results for CAS-TKA show improvement in alignment, and early clinical outcomes have revealed promising results, with longer-term data and medium-term survival analysis recently emerging showing small benefits over conventional TKA. RTKA represents another phase of development. Early results show similar trends to that of CAS TKA with longer-term data still to come.

Translational applications of photopolymerizable hydrogels for cartilage repair
Tập 6 Số 1 - 2019
Wenxia Meng, Liang Gao, Jagadeesh K. Venkatesan, Guanglin Wang, Henning Madry, Magali Cucchiarini
AbstractBackground

Articular cartilage lesions generated by trauma or osteoarthritis are the most common causes of pain and disability in patients.

Abstract

The development of photopolymerizable hydrogels has allowed for significant advances in cartilage repair procedures. Such three-dimensional (3D) networks of polymers that carry large amounts of water can be created to resemble the physical characteristics of the articular cartilage and be delivered into ill-defined cartilage defects as a liquid solution prior to polymerization in vivo for perfect fit with the surrounding native tissue. These hydrogels offer an adapted environment to encapsulate and propagate regenerative cells in 3D cultures for cartilage repair. Among them, mesenchymal stem cells and chondrocytes may represent the most adapted sources for implantation. They also represent platforms to deliver therapeutic, biologically active factors that promote 3D cell differentiation and maintenance for in vivo repair.

Conclusion

This review presents the benefits of photopolymerization of hydrogels and describes the photoinitiators and materials in current use for enhanced cartilage repair.

Comparing the efficacy of dual Platelet-Rich Plasma (PRP) and Hyaluronic Acid (HA) therapy with PRP-alone therapy in the treatment of knee osteoarthritis: a systematic review and meta-analysis
Tập 8 Số 1 - 2021
Angeline Ai Ling Aw, Jun Jie Leeu, Xinyu Tao, Hamid Rahmatullah Bin Abd Razak
Abstract Purpose

This study aims to compare the efficacy of a dual therapy of Platelet-Rich Plasma (PRP) and Hyaluronic Acid (HA) compared with PRP-alone therapy in the treatment of knee osteoarthritis (KOA).

Methods

PubMed, Embase, CINAHL, SCOPUS, Cochrane Library, grey literature and bibliographic references were searched from inception to January 2021. Only randomized controlled trials (RCTs) and retrospective cohort studies comparing the effect of PRP and HA versus PRP-alone therapy for KOA were included. Literature retrieval and data extraction were conducted by three independent reviewers. Pooled analysis of Visual Analogue Scale (VAS), Western Ontario and McMaster Universities Arthritis Index (WOMAC), International Knee Documentation Committee (IKDC) scores and adverse events were conducted.

Results

Ten studies (7 RCTs, 3 cohort studies) involving 983 patients were covered. Dual PRP and HA therapy resulted in significant reduction in VAS compared to PRP-alone therapy at 4–6 weeks (P < 0.00001) and 12 months (P < 0.00001). Dual therapy resulted in better WOMAC score improvement at 3 (P = 0.02), 6 (P = 0.05) and 12 months (P < 0.0001) compared to PRP-alone therapy. The IKDC score for dual therapy was also higher at 6 months compared to PRP-alone therapy (P = 0.007). Regarding adverse events, dual therapy was generally safer than PRP-alone therapy (P = 0.02).

Conclusion

While there is a paucity of large high-quality Level I studies, current best evidence suggests that dual therapy with PRP and HA for KOA may be effective at providing pain relief and improvement in function up to 1 year following administration.

Level of evidence

II.

Return to sports after ACL injury 5 years from now: 10 things we must do
Tập 9 Số 1
Alli Gokeler, Alberto Grassi, Roy A.G. Hoogeslag, Albert van Houten, Tim Lehman, Caroline Bolling, Matthew Buckthorpe, Grant E. Norte, Anne Benjaminse, Pieter Heuvelmans, Stefano Di Paolo, Igor Tak, F. Villa
AbstractBackground

The outcome after ACL reconstruction (ACLR) is in general disappointing with unacceptable number of athletes that do not return to pre-injury level of sports, high re-injury rates, early development of osteoarthritis and shorter careers. Athletes after ACLR have high expectation to return to sports which is in contrast with the current outcomes. The aim of this manuscript is to present an overview of factors that are needed to be incorporated and to personalize the rehabilitation process for an athlete who has undergone an ACLR.

Level of evidence

4.

It is not ‘business as usual’ for orthopaedic surgeons in May 2020– the Austrian-German-Swiss experience
Tập 7 Số 1 - 2020
Michael Liebensteiner, Ismail Khosravi, Michael T. Hirschmann, Philipp R. Heuberer, Mo Saffarini, Martin Thaler
Abstract Purpose

To document the status-quo of orthopaedic health-care services as the COVID-19 pandemic recedes, and to determine the rate of resumption of orthopaedic surgery in the German-speaking countries in May 2020.

Methods

A prospective online survey was sent out to 4234 surgeons of the AGA - Society of Arthroscopy and Joint-Surgery (Gesellschaft für Arthroskopie und Gelenkchirurgie, AGA). The survey was created using SurveyMonkey software and consisted of 23 questions relating to the reduction of orthopaedic services at the participating centres and the impact that the pandemic is having on each surgeon.

Results

A total of 890 orthopaedic surgeons responded to the online survey. Approximately 90% of them experienced a reduction in their surgical caseload and patient contact. 38.7% stated that their institutions returned to providing diagnostic arthroscopies. 54.5% reported that they went back to performing anterior cruciate ligament reconstructions (ACLR), 62.6% were performing arthroscopic meniscus procedures, and 55.8% had resumed performing shoulder arthroscopy. Only 31.9% of the surgeons were able to perform elective total joint arthroplasty. 60% of the participants stated that they had suffered substantial financial loss due to the pandemic.

Conclusion

A gradual resumption of orthopaedic health-care services was observed in May 2020. Typical orthopaedic surgical procedures like ACLR, shoulder arthroscopy and elective total joint arthroplasty were reported to be currently performed by 54%, 56% and 32% of surgeons, respectively. Despite signs of improvement, it appears that there is a prolonged curtailment of orthopaedic health-care at present in the middle of Europe.