Journal of Experimental Orthopaedics

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Comparative in vitro treatment of mesenchymal stromal cells with GDF-5 and R57A induces chondrogenic differentiation while limiting chondrogenic hypertrophy
Journal of Experimental Orthopaedics - Tập 10 - Trang 1-11 - 2023
Manuel Weißenberger, Mike Wagenbrenner, Joachim Nickel, Rasmus Ahlbrecht, Torsten Blunk, Andre F. Steinert, Fabian Gilbert
Hypertrophic cartilage is an important characteristic of osteoarthritis and can often be found in patients suffering from osteoarthritis. Although the exact pathomechanism remains poorly understood, hypertrophic de-differentiation of chondrocytes also poses a major challenge in the cell-based repair of hyaline cartilage using mesenchymal stromal cells (MSCs). While different members of the transfo...... hiện toàn bộ
The effect of static stretching exercises on hip range of motion, pain, and disability in patients with non-specific low back pain
Journal of Experimental Orthopaedics - Tập 8 - Trang 1-6 - 2021
Mohamadreza Hatefi, Farideh Babakhani, Mohadeseh Ashrafizadeh
The benefits of providing static stretching exercise targeting the hips in patients with non-specific Low Back Pain (NSLBP) are not well established. The objective of the study was to verify the effects of static stretching on function, pain and range of motion on patients with non-specific Low Back Pain (NSLBP). Thirty females with NSLBP were randomly assigned to two control (n = 15) and experime...... hiện toàn bộ
Technical note: rectangular femoral tunnel for anterior cruciate ligament reconstruction using a new ultrasonic device: a feasibility study
Journal of Experimental Orthopaedics - - 2021
Romain Seil, Caroline Mouton, Christophe Jacquet
Abstract Purpose The goal of this preliminary report was to show the use of novel Ultrasound (US) technology for anterior cruciate ligament (ACL) reconstruction surgery and evaluate its feasibility for the creation of a rectangular femoral bone tunnel during an arthroscopic procedure in a human cada...... hiện toàn bộ
Impacted bone allograft personalised by a novel 3D printed customization kit produces high surgical accuracy in medial opening wedge high tibial osteotomy: a pilot study
Journal of Experimental Orthopaedics - Tập 10 - Trang 1-10 - 2023
Wouter Van Genechten, Annemieke Van Haver, Stijn Bartholomeeusen, Toon Claes, Nathalie Van Beek, Jozef Michielsen, Steven Claes, Peter Verdonk
Contemporary medial opening wedge high tibial osteotomy (MOWHTO) still seems to struggle with inconsistent accuracy outcomes. Our objective was to assess surgical accuracy and short-term clinical outcomes when using 3D planning and a patient-specific instrumentation (PSI) kit to prepare customized bone allografts. Thirty subjects (age 48y ± 13) were included in a double-center prospective case ser...... hiện toàn bộ
Reduction of pin tract infections during external fixation using cadexomer iodine
Journal of Experimental Orthopaedics - - 2020
M. Jansen, Nienke van Egmond, Esmee C Kester, S.C. Mastbergen, Floris P. J. G. Lafeber, Roel J.H. Custers
Abstract Purpose Knee joint distraction (KJD) is a joint-preserving treatment for younger osteoarthritis patients. KJD has shown positive results in regular care, but the external fixation frame often caused pin tract skin infections. Therefore, the use of cadexomer iodine was include...... hiện toàn bộ
Correction: Fixed-loop vs. adjustable-loop cortical button devices for femoral fixation in ACL reconstruction – a systematic review and meta-analysis
Journal of Experimental Orthopaedics - Tập 9 - Trang 1-1 - 2022
Simone Birkebæk Elmholt, Torsten Grønbech Nielsen, Martin Lind
Correction: Comparison of total cold-water immersion’s effects to ice massage on recovery from exercise-induced muscle damage
Journal of Experimental Orthopaedics -
Mohammed Ali Fakhro, Fatima AlAmeen, Rim Fayad
Biomechanical evaluation of a biomimetic spinal construct
Journal of Experimental Orthopaedics - Tập 1 - Trang 1-8 - 2014
Tian Wang, Jonathon R Ball, Mattew H Pelletier, William R Walsh
Laboratory spinal biomechanical tests using human cadaveric or animal spines have limitations in terms of disease transmission, high sample variability, decay and fatigue during extended testing protocols. Therefore, a synthetic biomimetic spine model may be an acceptable substitute. The goal of current study is to evaluate the properties of a synthetic biomimetic spine model; also to assess the m...... hiện toàn bộ
CARGEL Bioscaffold improves cartilage repair tissue after bone marrow stimulation in a minipig model
Journal of Experimental Orthopaedics - Tập 7 - Trang 1-11 - 2020
K. Hede, B. B. Christensen, M. L. Olesen, J. S. Thomsen, C. B. Foldager, M. C. Lind
To gain knowledge of the repair tissue in critically sized cartilage defects using bone marrow stimulation combined with CARGEL Bioscaffold (CB) compared with bone marrow stimulation (BMS) alone in a validated animal model. Six adult Göttingen minipigs received two chondral defects in each knee. The knees were randomized to either BMS combined with CB or BMS alone. The animals were euthanized afte...... hiện toàn bộ
A preclinical numerical assessment of a polyetheretherketone femoral component in total knee arthroplasty during gait
Journal of Experimental Orthopaedics - Tập 4 - Trang 1-8 - 2017
Lennert de Ruiter, Dennis Janssen, Adam Briscoe, Nico Verdonschot
Conventional total knee replacement designs show high success rates but in the long term, the stiff metal components may affect bone quality of the distal femur. In this study we introduce an all-polymer total knee replacement device containing a PEEK femoral component on an UHMWPE tibial implant and study its mechanical integrity, fixation, and stress shielding of the periprosthetic femur. The im...... hiện toàn bộ
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