Journal of Clinical Laboratory Analysis
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Clinical values of circular RNA 0000181 in the screening of gastric cancer
Journal of Clinical Laboratory Analysis - Tập 32 Số 4 - 2018
BackgroundCircular RNAs (circRNAs) are recently found involved in cancer
occurrence and development. However, their values in the diagnosis of gastric
cancers are largely unknown. In this study, we analyzed the values of
hsa_circ_0000181 in the diagnosis of gastric cancer.MethodsUsing divergent
primers, hsa_circ_0000181 expression levels in fresh gastric cancer tissues and
paired adjacent non‐tumo...
What are the cut‐off levels for IL‐6 and CRP in neonatal sepsis?
Journal of Clinical Laboratory Analysis - Tập 24 Số 6 - Trang 407-412 - 2010
AbstractNeonatal sepsis, characterized by systemic signs of infection in the
first month of life, remains an important clinical syndrome. Despite advances in
neonatology, it has high rates of mortality and morbidity. The combine or alone
usage of interleukin‐6 (IL‐6) and C‐reactive protein (CRP) has recently been
proven to be useful in the early diagnosis of sepsis in newborns. The study
included ...
Jacalin: A new laboratory tool in immunochemistry and cellular immunology
Journal of Clinical Laboratory Analysis - Tập 3 Số 4 - Trang 244-251 - 1989
AbstractIn recent years, a new lectin—jacalin—has raised the interest of
immunologists because of its original properties with respect to human
immunoglobulins and lymphocytes. Its structure and carbohydrate binding
specifity are now well documented, and it can be purified easily from jackfruit
seeds by ion exchange or affinity chromatography. The binding and precipitating
specificities of jacalin...
Comparative study of total protein, and total and lipid‐associated serum sialic acid levels in patients with type 2 diabetes mellitus
Journal of Clinical Laboratory Analysis - Tập 17 Số 4 - Trang 124-126 - 2003
AbstractThe aim of the present study was to investigate the serum total protein
(TP), total sialic acid (TSA), lipid‐associated sialic acid (LSA), LSA/TP, and
LSA/TP values in type 2 diabetes mellitus (DM) patients. Two study groups
(healthy controls and type 2 DM subjects) were examined. For the type 2 DM
group, 120 patients (60 females and 60 males) who had been diagnosed and treated
for type 2 ...
Review of in vivo pharmacokinetics and toxicology of phosphorothioate oligonucleotides
Journal of Clinical Laboratory Analysis - Tập 9 Số 2 - Trang 129-137 - 1995
Urokinase gene 3′‐UTR T/C polymorphism is associated with oral cancer
Journal of Clinical Laboratory Analysis - Tập 18 Số 5 - Trang 276-279 - 2004
AbstractUrokinase is thought to be involved in the formation of oral cancer,
although there is a lack of genetic evidence. Our aim was to study single
nucleotide polymorphisms in order to investigate the possibility. A total of 130
oral cancer patients and 105 controls were studied. Polymerase chain reaction
(PCR) based restriction analysis was used to identify the C/T polymorphism of
the urokinas...
Bilayer lipid membrane‐based electrochemical biosensors
Journal of Clinical Laboratory Analysis - Tập 2 Số 4 - Trang 256-264 - 1988
AbstractThis paper presents a brief review on the bilayer lipid membrane (BLM)
system and its potential applications as a chemical/biosensor. The applications
reviewed include substrate‐enzyme complexes, antigen‐antibody‐complement
interactions, electrochemical assay of drugs, as well as light‐sensitive BLMs
for optical sensors. Suggestions for improvements in the development of
BLM‐based electroc...
Prostate‐specific antigen and prostate gland volume: Correlation and clinical application
Journal of Clinical Laboratory Analysis - Tập 4 Số 2 - Trang 135-137 - 1990
AbstractWe studied 103 patients seen in our Prostate Cancer Detection Clinic to
determine whether a correlation exists between serum prostate‐specific antigen
(PSA) values and ultrasound‐calculated prostate gland volume. Seventy men (68%)
had a PSA value ≤ ng/ml (our upper limit of normal). The men were subclassified
by prostate gland volume at arbitrary break points. Twenty‐five men (24%) had a
p...
Sensitivity of the Standard Chlamydia trachomatis Culture Method Is Improved After One Additional In Vitro Passage
Journal of Clinical Laboratory Analysis - Tập 30 Số 5 - Trang 697-701 - 2016
BackgroundChlamydia trachomatis causes the most common bacterial sexually
transmitted infection (STI) worldwide. Although highly sensitive nucleic acid
amplification tests (NAATs) are used to routinely diagnose chlamydial infection,
C. trachomatis isolation by cell culture is still preferred for legal cases and
epidemiological studies because of its high specificity; however, the
sensitivity of tr...
Potential clinical applications of c‐reactive protein
Journal of Clinical Laboratory Analysis - Tập 4 Số 3 - Trang 231-235 - 1990
AbstractThis article reviews the clinical applications of C‐reactive protein
(CRP). This acute‐phase protein is a distinct and sensitive marker for
inflammation and tissue injury. It is a simple, fast, and relatively inexpensive
latex agglutination test. The aspects of CRP reviewed include diagnostic
support, serial measurements to evaluate disease course and therapeutic
response, and screening st...
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