Journal of Clinical Laboratory Analysis

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Clinical values of circular RNA 0000181 in the screening of gastric cancer
Journal of Clinical Laboratory Analysis - Tập 32 Số 4 - 2018
Qianfu Zhao, Shijun Chen, Tianwen Li, Bingxiu Xiao, Xinjun Zhang
BackgroundCircular RNAs (circRNAs) are recently found involved in cancer occurrence and development. However, their values in the diagnosis of gastric cancers are largely unknown. In this study, we analyzed the values of hsa_circ_0000181 in the diagnosis of gastric cancer.MethodsUsing divergen...... hiện toàn bộ
Jacalin: A new laboratory tool in immunochemistry and cellular immunology
Journal of Clinical Laboratory Analysis - Tập 3 Số 4 - Trang 244-251 - 1989
Pièrre Aucouturier, Nathalie Pineau, Jean‐Christophe Brugier, Edith Mihaesco, Françoise Duarte, F Skvaril, Jean‐Louis Preud'homme
AbstractIn recent years, a new lectin—jacalin—has raised the interest of immunologists because of its original properties with respect to human immunoglobulins and lymphocytes. Its structure and carbohydrate binding specifity are now well documented, and it can be purified easily from jackfruit seeds by ion exchange or affinity chromatography. The binding and preci...... hiện toàn bộ
Comparative study of total protein, and total and lipid‐associated serum sialic acid levels in patients with type 2 diabetes mellitus
Journal of Clinical Laboratory Analysis - Tập 17 Số 4 - Trang 124-126 - 2003
Suat Ekin, İsmail Meral, Handan Gündüz, Nihat Mert
AbstractThe aim of the present study was to investigate the serum total protein (TP), total sialic acid (TSA), lipid‐associated sialic acid (LSA), LSA/TP, and LSA/TP values in type 2 diabetes mellitus (DM) patients. Two study groups (healthy controls and type 2 DM subjects) were examined. For the type 2 DM group, 120 patients (60 females and 60 males) who had been ...... hiện toàn bộ
Prostate‐specific antigen and prostate gland volume: Correlation and clinical application
Journal of Clinical Laboratory Analysis - Tập 4 Số 2 - Trang 135-137 - 1990
R. Joseph Babaian, Robert B. Evans, Herbert A. Fritsche
AbstractWe studied 103 patients seen in our Prostate Cancer Detection Clinic to determine whether a correlation exists between serum prostate‐specific antigen (PSA) values and ultrasound‐calculated prostate gland volume. Seventy men (68%) had a PSA value ≤ ng/ml (our upper limit of normal). The men were subclassified by prostate gland volume at arbitrary break poin...... hiện toàn bộ
Sensitivity of the Standard Chlamydia trachomatis Culture Method Is Improved After One Additional In Vitro Passage
Journal of Clinical Laboratory Analysis - Tập 30 Số 5 - Trang 697-701 - 2016
Lili Shao, Yuanli Guo, Yong Jiang, Yuanjun Liu, Mei Wang, Cong You, Quanzhong Liu
BackgroundChlamydia trachomatis causes the most common bacterial sexually transmitted infection (STI) worldwide. Although highly sensitive nucleic acid amplification tests (NAATs) are used to routinely diagnose chlamydial infection, C. trachomatis isolation by cell culture is still preferred for legal ...... hiện toàn bộ
Potential clinical applications of c‐reactive protein
Journal of Clinical Laboratory Analysis - Tập 4 Số 3 - Trang 231-235 - 1990
Jonathan Okamura, Junko Miyagi, Keith Y. Terada, Y. Hokama
AbstractThis article reviews the clinical applications of C‐reactive protein (CRP). This acute‐phase protein is a distinct and sensitive marker for inflammation and tissue injury. It is a simple, fast, and relatively inexpensive latex agglutination test. The aspects of CRP reviewed include diagnostic support, serial measurements to evaluate disease course and thera...... hiện toàn bộ
Differential Diagnostics of Thalassemia Minor by Artificial Neural Networks Model
Journal of Clinical Laboratory Analysis - Tập 27 Số 6 - Trang 481-486 - 2013
Guy Barnhart-Magen, V. A. Gotlib, Rafael Marilus, Yulia Einav
Checklist for optimization and validation of real‐time PCR assays
Journal of Clinical Laboratory Analysis - Tập 23 Số 3 - Trang 145-151 - 2009
Marijke Raymaekers, Rita Smets, Brigitte Maes, Reinoud Cartuyvels
AbstractReal‐time polymerase chain reaction (PCR) is a frequently used technique in molecular diagnostics. To date, practical guidelines for the complete process of optimization and validation of commercial and in‐house developed molecular diagnostic methods are scare. Therefore, we propose a practical guiding principle for the optimization and validation of real‐t...... hiện toàn bộ
Cholesterol oxides and carcinogenesis
Journal of Clinical Laboratory Analysis - Tập 5 Số 3 - Trang 219-225 - 1991
Robert J. Morin, Bing Hu, Shi‐Kaung Peng, Alex Sevanian
AbstractExperimental evidence indicates a relationship between cholesterol α‐epoxide and skin cancer, and exposure of skin fibroblasts to ultraviolet radiation enduces formation of significant levels of this oxide. Colon cancer is also etiologically linked to cholesterol oxidation products. Higher than normal levels of cholestanetriol have been found in patients wi...... hiện toàn bộ
Multiplex polymerase chain reaction: A practical approach
Journal of Clinical Laboratory Analysis - Tập 16 Số 1 - Trang 47-51 - 2002
Panayotis Markoulatos, Nikolaos Siafakas, Maurice L.J. Moncany
AbstractConsiderable time and effort can be saved by simultaneously amplifying multiple sequences in a single reaction, a process referred to as multiplex polymerase chain reaction (PCR). Multiplex PCR requires that primers lead to amplification of unique regions of DNA, both in individual pairs and in combinations of many primers, under a single set of reaction co...... hiện toàn bộ
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