Journal of Clinical Laboratory Analysis
SCIE-ISI SCOPUS (1987-2023)
0887-8013
1098-2825
Mỹ
Cơ quản chủ quản: Wiley-Liss Inc. , WILEY
Lĩnh vực:
Public Health, Environmental and Occupational HealthHematologyImmunology and AllergyMicrobiology (medical)Biochemistry (medical)Medical Laboratory TechnologyClinical Biochemistry
Các bài báo tiêu biểu
Multiplex polymerase chain reaction: A practical approachAbstract Considerable time and effort can be saved by simultaneously amplifying multiple sequences in a single reaction, a process referred to as multiplex polymerase chain reaction (PCR). Multiplex PCR requires that primers lead to amplification of unique regions of DNA, both in individual pairs and in combinations of many primers, under a single set of reaction co... ... hiện toàn bộ
Tập 16 Số 1 - Trang 47-51 - 2002
Checklist for optimization and validation of real‐time PCR assaysAbstract Real‐time polymerase chain reaction (PCR) is a frequently used technique in molecular diagnostics. To date, practical guidelines for the complete process of optimization and validation of commercial and in‐house developed molecular diagnostic methods are scare. Therefore, we propose a practical guiding principle for the optimization and validation of real‐t... ... hiện toàn bộ
Tập 23 Số 3 - Trang 145-151 - 2009
Review of in vivo pharmacokinetics and toxicology of phosphorothioate oligonucleotides
Tập 9 Số 2 - Trang 129-137 - 1995
What are the cut‐off levels for IL‐6 and CRP in neonatal sepsis?Abstract Neonatal sepsis, characterized by systemic signs of infection in the first month of life, remains an important clinical syndrome. Despite advances in neonatology, it has high rates of mortality and morbidity. The combine or alone usage of interleukin‐6 (IL‐6) and C‐reactive protein (CRP) has recently been proven to be useful in the early diagnosis of sepsis... ... hiện toàn bộ
Tập 24 Số 6 - Trang 407-412 - 2010
Prostate‐specific antigen and prostate gland volume: Correlation and clinical applicationAbstract We studied 103 patients seen in our Prostate Cancer Detection Clinic to determine whether a correlation exists between serum prostate‐specific antigen (PSA) values and ultrasound‐calculated prostate gland volume. Seventy men (68%) had a PSA value ≤ ng/ml (our upper limit of normal). The men were subclassified by prostate gland volume at arbitrary break poin... ... hiện toàn bộ
Tập 4 Số 2 - Trang 135-137 - 1990
Clinical values of circular RNA 0000181 in the screening of gastric cancerBackground Circular RNAs (circRNAs) are recently found involved in cancer occurrence and development. However, their values in the diagnosis of gastric cancers are largely unknown. In this study, we analyzed the values of hsa_circ_0000181 in the diagnosis of gastric cancer. Methods Using divergen...
Tập 32 Số 4 - 2018
Potential clinical applications of c‐reactive proteinAbstract This article reviews the clinical applications of C‐reactive protein (CRP). This acute‐phase protein is a distinct and sensitive marker for inflammation and tissue injury. It is a simple, fast, and relatively inexpensive latex agglutination test. The aspects of CRP reviewed include diagnostic support, serial measurements to evaluate disease course and thera... ... hiện toàn bộ
Tập 4 Số 3 - Trang 231-235 - 1990
Cholesterol oxides and carcinogenesisAbstract Experimental evidence indicates a relationship between cholesterol α‐epoxide and skin cancer, and exposure of skin fibroblasts to ultraviolet radiation enduces formation of significant levels of this oxide. Colon cancer is also etiologically linked to cholesterol oxidation products. Higher than normal levels of cholestanetriol have been found in patients wi... ... hiện toàn bộ
Tập 5 Số 3 - Trang 219-225 - 1991
Detection of autoantibodies to ss‐a/ro by indirect immunofluorescence using a transfected and overexpressed human 60 kd ro autoantigen in hep‐2 cellsAbstract The objective of the study was to determine the sensitivity and specificity of an indirect immunofluorescence (IIF) assay using transfected HEp‐2 cells to detect anti‐SS‐A/Ro autoantibodies in human sera. Seventy‐three sera having SS‐A/Ro autoantibodies as determined by double immunodiffusion (ID) and immunoblotting (IB) were tested by IIF on a HEp‐2 cell s... ... hiện toàn bộ
Tập 9 Số 3 - Trang 218-224 - 1995
MPS screening methods, the berry spot and acid turbidity tests, cause a high incidence of false‐negative results in sanfilippo and morquio syndromesAbstract Because of differences in the types and quantities of glycosaminoglycans (GAGs) in various mucopolysaccharidoses (MPSs), MPS screening tests, including the Berry spot and acid turbidity tests, are not specific or sensitive enough for the preliminary diagnosis of MPS. A false‐negative result is common. We analyzed urine samples collected from 492 patients wh... ... hiện toàn bộ
Tập 16 Số 5 - Trang 253-258 - 2002