Journal of Cachexia, Sarcopenia and Muscle
SCOPUS (2010-2025)SCIE-ISI
2190-6009
2190-5991
Cơ quản chủ quản: WILEY , Wiley-Blackwell
Lĩnh vực:
Orthopedics and Sports MedicinePhysiology (medical)
Phân tích ảnh hưởng
Các bài báo tiêu biểu
SARC-F: a symptom score to predict persons with sarcopenia at risk for poor functional outcomes
Tập 7 Số 1 - Trang 28-36 - 2016
Sarcopenic obesity and myosteatosis are associated with higher mortality in patients with cirrhosis
Tập 7 Số 2 - Trang 126-135 - 2016
Mitochondria and ageing: role in heart, skeletal muscle and adipose tissue
Tập 8 Số 3 - Trang 349-369 - 2017
AbstractAge is the most important risk factor for most diseases. Mitochondria
play a central role in bioenergetics and metabolism. In addition, several lines
of evidence indicate the impact of mitochondria in lifespan determination and
ageing. The best‐known hypothesis to explain ageing is the free radical theory,
which proposes that cells, organs, and organisms age because they accumulate
reactiv...
Osteosarcopenic obesity: the role of bone, muscle, and fat on health
- 2014
Osteopenia/osteoporosis, sarcopenia, and obesity are commonly observed in the
process of aging, and recent evidence suggests a potential interconnection of
these syndromes with common pathophysiology. The term osteosarcopenic obesity
has been coined to describe the concurrent appearance of obesity in individuals
with low bone and muscle mass. Although our understanding of osteosarcopenic
obesity's...
Cancer cachexia: impact, mechanisms and emerging treatments
Tập 4 Số 2 - Trang 95-109 - 2013
Many forms of cancer present with a complex metabolic profile characterised by
loss of lean body mass known as cancer cachexia. The physical impact of cachexia
contributes to decreased patient quality of life, treatment success and survival
due to gross alterations in protein metabolism, increased oxidative stress and
systemic inflammation. The psychological impact also contributes to decreased
qu...
Elevated serum myostatin level is associated with worse survival in patients with liver cirrhosis
Tập 8 Số 6 - Trang 915-925 - 2017
AbstractBackgroundWe aimed to elucidate the relationship between serum myostatin
levels and other markers including skeletal muscle mass and to investigate the
influence of serum myostatin levels on survival for patients with liver
cirrhosis (LC).MethodsA total of 198 LC subjects were analysed in this study.
Myostatin levels were measured using stored sera. We retrospectively
investigated the rela...
Cancer cachexia prevention via physical exercise: molecular mechanisms
Tập 4 Số 2 - Trang 111-124 - 2013
Cancer cachexia is a debilitating consequence of disease progression,
characterised by the significant weight loss through the catabolism of both
skeletal muscle and adipose tissue, leading to a reduced mobility and muscle
function, fatigue, impaired quality of life and ultimately death occurring with
25–30 % total body weight loss. Degradation of proteins and decreased protein
synthesis contribut...
Role and potential mechanisms of anabolic resistance in sarcopenia
- 2012
There is pressing need to understand the aging process to better cope with its
associated physical and societal costs. The age‐related muscle wasting known as
sarcopenia is a major contributor to the problems faced by the elderly. By
hindering mobility and reducing strength, it greatly diminishes independence and
quality of life. In studying the factors that contribute to the development of
sarcop...
Potential therapeutic interventions for chronic kidney disease‐associated sarcopenia via indoxyl sulfate‐induced mitochondrial dysfunction
Tập 8 Số 5 - Trang 735-747 - 2017
AbstractBackgroundChronic kidney disease (CKD) patients experience skeletal
muscle wasting and decreased exercise endurance. Our previous study demonstrated
that indoxyl sulfate (IS), a uremic toxin, accelerates skeletal muscle atrophy.
The purpose of this study was to examine the issue of whether IS causes
mitochondria dysfunction and IS‐targeted intervention using AST‐120, which
inhibits IS accu...