Nutritional screening and early treatment of malnutrition in cancer patientsJournal of Cachexia, Sarcopenia and Muscle - Tập 2 - Trang 27-35 - 2011
Lidia Santarpia, Franco Contaldo, Fabrizio Pasanisi
Malnutrition is a frequent complication in patients with cancer and can negatively affect the outcome of treatments. On the other hand, side effects of anticancer therapies can also lead to inadequate nutrient intake and subsequent malnutrition. The nutritional screening aims to identify patients at risk of malnutrition for prompt treatment and/or careful follow-up. This manuscript highlights the ...... hiện toàn bộ
Osteosarcopenic obesity: the role of bone, muscle, and fat on healthJournal of Cachexia, Sarcopenia and Muscle - - 2014
Michael J. Ormsbee, Carla M. Prado, Jasminka Z. Ilich, Sarah A. Purcell, Mario Siervo, Abbey Folsom, Lynn B. Panton
Osteopenia/osteoporosis, sarcopenia, and obesity are commonly observed in the process of aging, and recent evidence suggests a potential interconnection of these syndromes with common pathophysiology. The term osteosarcopenic obesity has been coined to describe the concurrent appearance of obesity in individuals with low bone and muscle mass. Although our understand...... hiện toàn bộ
Cancer cachexia: impact, mechanisms and emerging treatmentsJournal of Cachexia, Sarcopenia and Muscle - Tập 4 Số 2 - Trang 95-109 - 2013
Vanessa Vaughan, Peter Martin, Paul Lewandowski
Many forms of cancer present with a complex metabolic profile characterised by loss of lean body mass known as cancer cachexia. The physical impact of cachexia contributes to decreased patient quality of life, treatment success and survival due to gross alterations in protein metabolism, increased oxidative stress and systemic inflammation. The psychological impact ...... hiện toàn bộ
Temporal development of muscle atrophy in murine model of arthritis is related to disease severityJournal of Cachexia, Sarcopenia and Muscle - Tập 4 - Trang 231-238 - 2013
Lidiane I. Filippin, Vivian N. Teixeira, Paula R. Viacava, Priscila S. Lora, Laura L. Xavier, Ricardo M. Xavier
Rheumatoid arthritis (RA) is an inflammatory autoimmune disease of unknown etiology, affecting mainly the joint but also other tissues. RA patients usually present weakness and muscle atrophy, nonarticular manifestations of the disease. Although causing great impact, the understanding of muscle atrophy, its development, and the mechanisms involved is still very limited. The objective of this study...... hiện toàn bộ
l‐carnitine and cancer cachexia: Clinical and experimental aspectsJournal of Cachexia, Sarcopenia and Muscle - Tập 2 Số 1 - Trang 37-44 - 2011
Renata Silvério, Alessandro Laviano, Filippo Rossi Fanelli, Marília Seelaender
Cancer cachexia is a multifaceted syndrome characterized, among many symptoms, by extensive muscle wasting. Chronic systemic inflammation, partly triggered and sustained by cytokines, as well as increased oxidative stress contributes to the pathogenesis of this complex metabolic disorder.
l‐carnitine plays a central role in the metabolism of fatt...... hiện toàn bộ
Age- and gender-dependent values of skeletal muscle mass in healthy children and adolescentsJournal of Cachexia, Sarcopenia and Muscle - Tập 3 - Trang 25-29 - 2011
Colin E. Webber, Ronald D. Barr
Skeletal muscle mass (SMM) can be extracted from whole-body scans obtained by X-ray-based dual-photon absorptiometry (DXA). There is a need to establish expected age-dependent values for children and adolescents. Appendicular lean tissue mass (ALM) was extracted from whole-body DXA scans in 140 healthy children and adolescents (68 females and 72 males). Whole-body SMM was calculated from ALM using...... hiện toàn bộ
Breakthrough in cachexia treatment through a novel selective androgen receptor modulator?!Journal of Cachexia, Sarcopenia and Muscle - Tập 2 - Trang 121-123 - 2011
Thomas Thum, Jochen Springer
Cachexia, and particularly the loss of metabolically active lean tissue, leads to increased morbidity and mortality in affected patients. An impairment of strength and functional status is usually associated with cachexia. A variety of anabolic and appetite-stimulating agents have been studied in patients with cachexia caused by various underlying diseases. Overall, these studies have demonstrated...... hiện toàn bộ