Whole-Genome Analysis of the Methyl tert -Butyl Ether-Degrading Beta-Proteobacterium Methylibium petroleiphilum PM1Journal of Bacteriology - Tập 189 Số 5 - Trang 1931-1945 - 2007
Staci R. Kane, Anu Chakicherla, Patrick Chain, Radomir Schmidt, Maria Shin, Tina C. Legler, Kate M. Scow, Frank W. Larimer, Susan Lucas, Paul M. Richardson, Krassimira R. Hristova
ABSTRACT Methylibium petroleiphilum PM1 is a methylotroph distinguished by its
ability to completely metabolize the fuel oxygenate methyl tert -butyl ether
(MTBE). Strain PM1 also degrades aromatic (benzene, toluene, and xylene) and
straight-chain (C 5 to C 12 ) hydrocarbons present in petroleum products.
Whole-genome analysis of PM1 revealed an ∼4-Mb circular chromosome and an
∼600-kb megaplasmid... hiện toàn bộ
Comparative Genome Sequence Analysis of Multidrug-Resistant Acinetobacter baumanniiJournal of Bacteriology - Tập 190 Số 24 - Trang 8053-8064 - 2008
Mark D. Adams, Karrie Goglin, Neil Molyneaux, Kristine M. Hujer, Heather Lavender, Jennifer J. Jamison, Ian J. MacDonald, Kristienna M. Martin, Thomas A. Russo, Anthony A. Campagnari, Andrea M. Hujer, Robert A. Bonomo, Steven R. Gill
ABSTRACT The recent emergence of multidrug resistance (MDR) in Acinetobacter
baumannii has raised concern in health care settings worldwide. In order to
understand the repertoire of resistance determinants and their organization and
origins, we compared the genome sequences of three MDR and three
drug-susceptible A. baumannii isolates. The entire MDR phenotype can be
explained by the acquisition o... hiện toàn bộ
Cell Death in Pseudomonas aeruginosa Biofilm DevelopmentJournal of Bacteriology - Tập 185 Số 15 - Trang 4585-4592 - 2003
Jeremy S. Webb, Lyndal S. Thompson, S. R. James, Tim Charlton, Tim Tolker‐Nielsen, Birgit Koch, Michael Givskov, Staffan Kjelleberg
ABSTRACT Bacteria growing in biofilms often develop multicellular,
three-dimensional structures known as microcolonies. Complex differentiation
within biofilms of Pseudomonas aeruginosa occurs, leading to the creation of
voids inside microcolonies and to the dispersal of cells from within these
voids. However, key developmental processes regulating these events are poorly
understood. A normal comp... hiện toàn bộ
Involvement of Nitric Oxide in Biofilm Dispersal of Pseudomonas aeruginosaJournal of Bacteriology - Tập 188 Số 21 - Trang 7344-7353 - 2006
Nicolas Barraud, Daniel J. Hassett, Sung Hei Hwang, Stuart A. Rice, Staffan Kjelleberg, Jeremy S. Webb
ABSTRACT Bacterial biofilms at times undergo regulated and coordinated dispersal
events where sessile biofilm cells convert to free-swimming, planktonic
bacteria. In the opportunistic pathogen Pseudomonas aeruginosa , we previously
observed that dispersal occurs concurrently with three interrelated processes
within mature biofilms: (i) production of oxidative or nitrosative
stress-inducing molecul... hiện toàn bộ
Nitric Oxide Signaling inPseudomonas aeruginosaBiofilms Mediates Phosphodiesterase Activity, Decreased Cyclic Di-GMP Levels, and Enhanced DispersalJournal of Bacteriology - Tập 191 Số 23 - Trang 7333-7342 - 2009
Nicolas Barraud, David Schleheck, Janosch Klebensberger, Jeremy S. Webb, Daniel J. Hassett, Stuart A. Rice, Staffan Kjelleberg
ABSTRACTBacteria in biofilms often undergo active dispersal events and revert to
a free-swimming, planktonic state to complete the biofilm life cycle. The
signaling molecule nitric oxide (NO) was previously found to trigger biofilm
dispersal in the opportunistic pathogenPseudomonas aeruginosaat low, nontoxic
concentrations (N. Barraud, D. J. Hassett, S. H. Hwang, S. A. Rice, S.
Kjelleberg, and J. ... hiện toàn bộ
Effects of Escherichia coli dnaE antimutator alleles in a proofreading-deficient mutD5 strainJournal of Bacteriology - Tập 177 Số 20 - Trang 5979-5986 - 1995
Iwona J. Fijałkowska, Roel M. Schaaper
We have previously isolated seven mutants of Escherichia coli which replicate
their DNA with increased fidelity. These mutants were isolated as suppressors of
the elevated mutability of a mismatch-repair-defective mutL strain. Each mutant
was shown to contain a single amino acid substitution in the dnaE gene product,
the alpha (i.e., polymerase) subunit of DNA polymerase III holoenzyme
responsible... hiện toàn bộ
The genes involved in production of and immunity to sakacin A, a bacteriocin from Lactobacillus sake Lb706Journal of Bacteriology - Tập 177 Số 8 - Trang 2125-2137 - 1995
Lars Axelsson, A. Holck
Sakacin A is a small, heat-stable, antilisterial bacteriocin produced by
Lactobacillus sake Lb706. The nucleotide sequence of a 8,668-bp fragment, shown
to contain all information necessary for sakacin A production and immunity, was
determined. The sequence revealed the presence of two divergently transcribed
operons. The first encompassed the structural gene sapA (previously designated
sakA) and ... hiện toàn bộ
Influence of impaired chaperone or secretion function on SecB production in Escherichia coliJournal of Bacteriology - Tập 178 Số 21 - Trang 6097-6104 - 1996
Jörg P. Müller
The efficient export of proteins through the cytoplasmic membrane of Escherichia
coli requires chaperones to maintain protein precursors in a
translocation-competent conformation. In addition to SecB, the major chaperone
facilitating export of particular precursors, heat shock-induced chaperones
DnaK-DnaJ and GroEL-GroES are also involved in this process. By use of
secB'-lacZ gene fusions and immu... hiện toàn bộ
Effects of signal sequence mutations on the kinetics of alkaline phosphatase export to the periplasm in Escherichia coliJournal of Bacteriology - Tập 167 Số 1 - Trang 160-167 - 1986
S Michaelis, J.F. Hunt, Jean‐Pierre Jacquot
We isolated a collection of mutants defective in the export of alkaline
phosphatase to the periplasm. Two classes of mutants were obtained: one class
with lesions unlinked to the phoA gene and a second class harboring linked
mutations. Among the former class, one mutant is cold sensitive for growth and
may be defective in a component of the Escherichia coli secretory apparatus.
Included in the lat... hiện toàn bộ