Endothelial cell activation and neovascularization are prominent in dermatomyositis Tập 3 Số 1 - 2006
Kanneboyina Nagaraju, Lisa G. Rider, Chenguang Fan, Yi Wen Chen, Megan Mitsak, Rashmi Rawat, Kathleen Patterson, Cecilia Grundtman, Frederick W. Miller, Paul H. Plötz, Eric P. Hoffman, Ingrid E. Lundberg
Abstract Background While vascular and immune abnormalities are common in
juvenile and adult dermatomyositis (DM), the molecular changes that contribute
to these abnormalities are not clear. Therefore, we investigated pathways that
facilitate new blood vessel formation and dendritic cell migration in
dermatomyositis. Methods Muscle biopsies from subjects with DM (9 children and 6
adults) and non-m... hiện toàn bộ
N-acetyl-L-cysteine ameliorates the inflammatory disease process in experimental autoimmune encephalomyelitis in Lewis rats Tập 2 - Trang 1-11 - 2005
Romesh Stanislaus, Anne G Gilg, Avtar K Singh, Inderjit Singh
We report that N-acetyl-L-cysteine (NAC) treatment blocked induction of TNF-α,
IL-1β, IFN-γ and iNOS in the CNS and attenuated clinical disease in the myelin
basic protein induced model of experimental allergic encephalomyelitis (EAE) in
Lewis rats. Infiltration of mononuclear cells into the CNS and induction of
inflammatory cytokines and iNOS in multiple sclerosis (MS) and EAE have been
implicate... hiện toàn bộ
Transfer of efficient anti-melanocyte T cells from vitiligo donors to melanoma patients as a novel immunotherapeutical strategy Tập 2 - Trang 1-5 - 2005
Belinda Palermo, Silvia Garbelli, Stefania Mantovani, Claudia Giachino
Vitiligo is a relatively common progressive depigmentary condition that is
believed to be due to the autoimmune-mediated loss of epidermal melanocytes.
High frequencies of self-reactive T lymphocytes directed toward melanocyte
differentiation antigens are found in vitiligo patients and might be directly
responsible for the pathogenesis of the disease. An interesting aspect of
vitiligo is its relat... hiện toàn bộ
Association of Epstein-Barr virus antibody titers with a human IL-10 promoter polymorphism in Japanese women Tập 5 - Trang 1-5 - 2008
Yutaka Yasui, Nobuyuki Hamajima, Tsuneya Nakamura, Noha Sharaf El-Din, Kazuo Tajima, John D Potter
Multiple sclerosis (MS) risk, over 10-fold higher in Western than in Asian
countries, is associated with elevated IgG antibody titers against Epstein-Barr
viral capcid antigen (anti-EBVCA IgG titers). Given the 84% homology of the open
reading frame BCRF1 of Epstein-Barr virus (EBV) to human interleukin 10 (hIL-10)
and the remarkable Caucasian-vs.-Asian population differences in hIL-10 gene
promot... hiện toàn bộ
Retraction Note to: analysis of the TCR alpha and beta chain CDR3 spectratypes in the peripheral blood of patients with Systemic Lupus Erythematosus Tập 5 - Trang 1-1 - 2008
Wei Luo, Li Ma, Qian Wen, Xin-Sheng Yao, Na Wang, Hong-Yun Zou, Ming-Qian Zhou, Ying Lin, Zhen-Qiang Wu, Xiao-Wei He, Ju-Fang Wang, Xiao-Ning Wang
Why do we need a new journal in autoimmunity? Tập 1 - Trang 1-3 - 2004
David D'Cruz, Vitaly Ablamunits
A new online Journal of Autoimmune Diseases is created as an independent open
access journal. In addition to the obvious advantages of the open access, the
Journal will practice a double-blind reviewing of the manuscripts, which means
that both the reviewers and the authors remain anonymous to each other. We
believe that such a policy will reduce the influence of personal and other
non-scientific ... hiện toàn bộ
The revised international autoimmune hepatitis score in chronic liver diseases including autoimmune hepatitis/overlap syndromes and autoimmune hepatitis with concurrent other liver disorders Tập 4 - Trang 1-12 - 2007
Panagiotis A Papamichalis, Kalliopi Zachou, George K Koukoulis, Aikaterini Veloni, Efthimia G Karacosta, Lampros Kypri, Ioannis Mamaloudis, Stella Gabeta, Eirini I Rigopoulou, Ansgar W Lohse, George N Dalekos
We conducted a study in order to determine the usefulness and diagnostic value
of International Autoimmune Hepatitis Group (IAHG) score in non-autoimmune
hepatitis (AIH) hepatic disorders as well as in AIH/overlap syndromes and in
cases with coexistence of AIH and other liver diseases. We applied the IAHG
score in 423 patients with liver diseases excluding patients with AIH,
AIH/overlap syndromes ... hiện toàn bộ
Lack of correlation between the levels of soluble cytotoxic T-lymphocyte associated antigen-4 (CTLA-4) and the CT-60 genotypes Tập 2 - Trang 1-6 - 2005
Sharad Purohit, Robert Podolsky, Christin Collins, Weipeng Zheng, Desmond Schatz, Andy Muir, Diane Hopkins, Yi-Hua Huang, Jin-Xiong She
Cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) plays a critical role in
downregulation of antigen-activated immune response and polymorphisms at the
CTLA-4 gene have been shown to be associated with several autoimmune diseases
including type-1 diabetes (T1D). The etiological mutation was mapped to the
CT60-A/G single nucleotide polymorphism (SNP) that is believed to control the
processing an... hiện toàn bộ
Are classification criteria for vasculitis useful in clinical practice? Observations and lessons from Colombia Tập 6 - Trang 1-10 - 2009
Paúl Alejandro Méndez Patarroyo, José Félix Restrepo, Samanda Adriana Rojas, Federico Rondón, Eric L Matteson, Antonio Iglesias-Gamarra
Idiopathic systemic vasculitis represents a group of clinical entities having
non-specific etiology with the common characteristic of acute or chronic
inflammatory compromise of the small and large vessels walls, associated with
fibrinoid necrosis. To describe the most common inflammatory vascular diseases
in a long historical cohort of patients from San Juan de Dios Hospital located
in Bogota, Co... hiện toàn bộ