Endothelial cell activation and neovascularization are prominent in dermatomyositis Tập 3 Số 1 - 2006
Kanneboyina Nagaraju, Lisa G. Rider, Chenguang Fan, Yi Wen Chen, Megan Mitsak, Rashmi Rawat, Kathleen Patterson, Cecilia Grundtman, Frederick W. Miller, Paul H. Plötz, Eric P. Hoffman, Ingrid E. Lundberg
Abstract Background While vascular and immune abnormalities are common in
juvenile and adult dermatomyositis (DM), the molecular changes that contribute
to these abnormalities are not clear. Therefore, we investigated pathways that
facilitate new blood vessel formation and dendritic cell migration in
dermatomyositis. Methods Muscle biopsies from subjects with DM (9 children and 6
adults) and non-m... hiện toàn bộ
Evaluation of antibodies against human HSP60 in patients with MPO-ANCA associated glomerulonephritis: a cohort study Tập 3 - Trang 1-7 - 2006
Marjan C Slot, Ruud Theunissen, Pieter van Paassen, Jan GMC Damoiseaux, Jan Willem Cohen Tervaert
Human Heat Shock Protein 60 (hHSP60) has been implicated in autoimmunity through
molecular mimicry, based on the high degree of homology with HSP65 of
micro-organisms leading to autoimmune recognition of the human protein.
Additionally, sequence homology between hHSP60 and myeloperoxidase (MPO) has
been described. MPO is a major autoantigen in vasculitis associated with
antineutrophil cytoplasmic ... hiện toàn bộ
Insulin expressing hepatocytes not destroyed in transgenic NOD mice Tập 1 - Trang 1-12 - 2004
Muhammad T Tabiin, Christopher P White, Grant Morahan, Bernard E Tuch
The liver has been suggested as a suitable target organ for gene therapy of Type
1 diabetes. However, the fundamental issue whether insulin-secreting hepatocytes
in vivo will be destroyed by the autoimmune processes that kill pancreatic β
cells has not been fully addressed. It is possible that the insulin secreting
liver cells will be destroyed by the immune system because hepatocytes express
majo... hiện toàn bộ
Cerebrovascular disease associated with antiphospholipid antibodies: more questions than answers Tập 3 - Trang 1-7 - 2006
Carolyn Hawkins, Paul Gatenby, Roger Tuck, Gytis Danta, Colin Andrews
Neurological syndromes occur in a significant number of patients with
antiphospholipid antibodies. The optimal management for these patients however
remains uncertain. Our study is a descriptive analysis looking retrospectively
at 45 patients who presented to the principal tertiary referral centre in the
Australian Capital Territory, with either cerebral arterial or venous thrombosis
for which the... hiện toàn bộ
Why do we need a new journal in autoimmunity? Tập 1 - Trang 1-3 - 2004
David D'Cruz, Vitaly Ablamunits
A new online Journal of Autoimmune Diseases is created as an independent open
access journal. In addition to the obvious advantages of the open access, the
Journal will practice a double-blind reviewing of the manuscripts, which means
that both the reviewers and the authors remain anonymous to each other. We
believe that such a policy will reduce the influence of personal and other
non-scientific ... hiện toàn bộ
Retraction Note to: analysis of the TCR alpha and beta chain CDR3 spectratypes in the peripheral blood of patients with Systemic Lupus Erythematosus Tập 5 - Trang 1-1 - 2008
Wei Luo, Li Ma, Qian Wen, Xin-Sheng Yao, Na Wang, Hong-Yun Zou, Ming-Qian Zhou, Ying Lin, Zhen-Qiang Wu, Xiao-Wei He, Ju-Fang Wang, Xiao-Ning Wang
Transfer of efficient anti-melanocyte T cells from vitiligo donors to melanoma patients as a novel immunotherapeutical strategy Tập 2 - Trang 1-5 - 2005
Belinda Palermo, Silvia Garbelli, Stefania Mantovani, Claudia Giachino
Vitiligo is a relatively common progressive depigmentary condition that is
believed to be due to the autoimmune-mediated loss of epidermal melanocytes.
High frequencies of self-reactive T lymphocytes directed toward melanocyte
differentiation antigens are found in vitiligo patients and might be directly
responsible for the pathogenesis of the disease. An interesting aspect of
vitiligo is its relat... hiện toàn bộ
Are classification criteria for vasculitis useful in clinical practice? Observations and lessons from Colombia Tập 6 - Trang 1-10 - 2009
Paúl Alejandro Méndez Patarroyo, José Félix Restrepo, Samanda Adriana Rojas, Federico Rondón, Eric L Matteson, Antonio Iglesias-Gamarra
Idiopathic systemic vasculitis represents a group of clinical entities having
non-specific etiology with the common characteristic of acute or chronic
inflammatory compromise of the small and large vessels walls, associated with
fibrinoid necrosis. To describe the most common inflammatory vascular diseases
in a long historical cohort of patients from San Juan de Dios Hospital located
in Bogota, Co... hiện toàn bộ
Association of Epstein-Barr virus antibody titers with a human IL-10 promoter polymorphism in Japanese women Tập 5 - Trang 1-5 - 2008
Yutaka Yasui, Nobuyuki Hamajima, Tsuneya Nakamura, Noha Sharaf El-Din, Kazuo Tajima, John D Potter
Multiple sclerosis (MS) risk, over 10-fold higher in Western than in Asian
countries, is associated with elevated IgG antibody titers against Epstein-Barr
viral capcid antigen (anti-EBVCA IgG titers). Given the 84% homology of the open
reading frame BCRF1 of Epstein-Barr virus (EBV) to human interleukin 10 (hIL-10)
and the remarkable Caucasian-vs.-Asian population differences in hIL-10 gene
promot... hiện toàn bộ