Journal of Applied Genetics
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Polymorphisms in intron 1 of the porcinePOU1F1 gene
Journal of Applied Genetics - Tập 48 - Trang 371-374 - 2007
This study was conducted to detect polymorphisms in intron 1 of porcinePOU1F1 (POU domain, class 1, transcription factor1, Pit1, renamed asPOU1F1) by comparative sequencing. Within the intron, 23 sites of variation were identified, including 16 single-nucleotide substitutions, 4 single-nucleotide indels, 2 short (3-bp and 17-bp), and one long (313-bp) indels. Several important regulatory motifs we...... hiện toàn bộ
Tip60: updates
Journal of Applied Genetics - Tập 59 - Trang 161-168 - 2018
The maintenance of genome integrity is essential for organism survival. Therefore, eukaryotic cells possess many DNA repair mechanisms in response to DNA damage. Acetyltransferase, Tip60, plays a central role in ATM and p53 activation which are involved in DNA repair. Recent works uncovered the roles of Tip60 in ATM and p53 activation and how Tip60 is recruited to double-strand break sites. Moreov...... hiện toàn bộ
Using machine learning and partial dependence to evaluate robustness of best linear unbiased prediction (BLUP) for phenotypic values
Journal of Applied Genetics -
A new assay based on terminal restriction fragment length polymorphism of homocitrate synthase gene fragments for Candida species identification
Journal of Applied Genetics - Tập 58 - Trang 409-414 - 2017
Candida sp. have been responsible for an increasing number of infections, especially in patients with immunodeficiency. Species-specific differentiation of Candida sp. is difficult in routine diagnosis. This identification can have a highly significant association in therapy and prophylaxis. This work has shown a new application of the terminal restriction fragment length ...... hiện toàn bộ
Genetic variation in the efficiency of nitrogen utilization and photosynthetic activity of flag leaves among the old and modern germplasm of winter wheat
Journal of Applied Genetics - Tập 47 - Trang 231-237 - 2006
Genotypic variation in major components of the efficiency of nitrogen utilization and photosynthetic activity of flag leaves among old (released 1881–1963) and modern (released 1969–2003) cultivars of winter wheat was studied in field conditions under varied N fertilization levels (110, 90 and 80 kg N ha−1). Significant genotypic differences were observed for all characters. Their heritabilities r...... hiện toàn bộ
Analyses of air samples for ascospores ofLeptosphaeria maculans andL.biglobosa by light microscopy and molecular techniques
Journal of Applied Genetics - Tập 50 Số 4 - Trang 411-419 - 2009
Undescribed wheat gene for partial leaf rust and stripe rust resistance from Thatcher derivatives RL6058 and 90RN249 carryingLr34
Journal of Applied Genetics - Tập 50 - Trang 199-204 - 2009
Inheritance of partial leaf rust and stripe rust resistance of a Thatcher wheat 90RN2491, earlier reported to carry two doses of the gene pairLr34-Yr18 and the reference line RL6058 (6*Thatcher/PI58548) for theLr34-Yr18 gene pair was studied against predominant and highly virulent Indian races. Thatcher derivatives 90RN2491 and RL6058 were intercrossed as well as crossed with the leaf rust and str...... hiện toàn bộ
Isolation, sequence identification and tissue expression profiles of 3 novel porcine genes:ASPA, NAGA, andHEXA
Journal of Applied Genetics - Tập 49 - Trang 257-261 - 2008
The complete coding sequences of 3 porcine genes —ASPA, NAGA, andHEXA — were amplified by the reverse transcriptase polymerase chain reaction (RT-PCR) based on the conserved sequence information of the mouse or other mammals and referenced pig ESTs. These 3 novel porcine genes were then deposited in the NCBI database and assigned GeneIDs: 100142661, 100142664 and 100142667. The phylogenetic tree a...... hiện toàn bộ
Wnt pathway antagonists, SFRP1, SFRP2, SOX17, and PPP2R2B, are methylated in gliomas and SFRP1 methylation predicts shorter survival
Journal of Applied Genetics - Tập 57 - Trang 189-197 - 2015
The deregulation of Wnt signaling is observed in various cancers, including gliomas, and might be related to the methylation of the genes encoding antagonists of this signaling pathway. The aim of the study was to assess the methylation status of the promoter regions of six Wnt negative regulators and to determine their prognostic value in clinical samples of gliomas of different grades. The methy...... hiện toàn bộ
Carrier status for 3 most frequentCFTR mutations in Polish PCD/KS patients: lack of association with the primary ciliary dyskinesia phenotype
Journal of Applied Genetics - Tập 48 - Trang 85-88 - 2007
We screened a large group of primary ciliary dyskinesia/Kartagener syndrome (PCD/KS) patients and their siblings (148 patients from 126 unrelated families) for the presence of theCFTR mutations that are most frequently found in the Polish population: the severe F508del and 2,3del21kb, and the mild 3849+10kbC > T. No statistically significant increase in the frequency of these mutations was found i...... hiện toàn bộ
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