Journal of Applied Genetics

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Portuguese wild hop diversity assessment by fast SNP genotyping using high-resolution melting
Journal of Applied Genetics - Tập 63 - Trang 103-114 - 2021
Julio C. Machado, Miguel A. Faria, Ana Maria Barata, Isabel Gomes da Silva, Andreja Cerenak, Isabel M. P. L. V. O. Ferreira
A set of seven SNP markers was used to evaluate the genetic diversity of wild Portuguese hops in comparison with commercial cultivars. A collection of 110 wild genotypes and 33 cultivars was characterized by a high-resolution melting analysis of short amplicons targeting SNP loci. Most of the 143 genotypes (75%) could be differentiated. Phylogenetic analysis showed three main clusters, one include...... hiện toàn bộ
Modulation of lncRNA NEAT1 overturns the macrophages based immune response in M. tuberculosis infected patients via miR-373 regulation
Journal of Applied Genetics - - Trang 1-9 - 2023
Fahad M. Aldakheel, Rabbani Syed, Musthaq Ahmed, Tao Xu
There is a lack of studies which explore and clarify the interactions that occur between host macrophage and Mycobacterium tuberculosis with regard to microRNA such as LNCNEAT1 and miR-373. The current study determines the mechanisms involved in the control of M. tuberculosis infection by macrophage using LNCNEAT1 and miR-373. The researchers collected different samples from healthy individuals, p...... hiện toàn bộ
Craniosynostosis as a clinical and diagnostic problem: molecular pathology and genetic counseling
Journal of Applied Genetics - - 2018
Anna Kutkowska-Kaźmierczak, Monika Gos, Ewa Obersztyn
Craniosynostosis (occurrence: 1/2500 live births) is a result of premature fusion of cranial sutures, leading to alterations of the pattern of cranial growth, resulting in abnormal shape of the head and dysmorphic facial features. In approximately 85% of cases, the disease is isolated and nonsyndromic and mainly involves only one suture. Syndromic craniosynostoses such as Crouzon, Apert, Pfeiffer,...... hiện toàn bộ
Genetic dissection of green pod yield in dolichos bean, an orphan vegetable legume, using new molecular markers
Journal of Applied Genetics -
Vinayak Spoorthi, S. Ramesh, N. Sunitha, Vedashree, P. V. Vaijayanthi, C. T. A. Kumar
Identification of mutations in the HVR1 and PKR-BD regions in HCV-infected patients resistant to PEG-IFNα/RBV therapy
Journal of Applied Genetics - Tập 56 - Trang 403-409 - 2015
M. Holysz, K. Bialas, P. Migdalski, D. Kmieciak, W. H. Trzeciak
The identification of mutations in the HVR1 region of hepatitis type C virus (HCV) is time-consuming and expensive, and there is a need for a rapid, inexpensive method of screening for these mutations to predict the ineffectiveness of pegylated interferon alpha combined with ribavirin (PEG-IFNα/RBV) therapy. The project was designed to evaluate the usefulness of the high resolution melting (HRM) t...... hiện toàn bộ
No recovery of T-cell receptor excision circles (TRECs) after non-myeloablative allogeneic hematopoietic stem cell transplantation is correlated with the onset of GvHD
Journal of Applied Genetics - Tập 48 - Trang 397-404 - 2007
Grzegorz K. Przybylski, Karl-A. Kreuzer, Wolfgang Siegert, Christian A. Schmidt
Improper T-cell reconstitution with its consequences, graft-vs-host disease (GvHD) and outbreak of viral infections, is the major cause of morbidity and mortality after hematopoietic stem cell transplantation (HSCT). To determine the factors affecting reconstitution of naive T-cells after non-myeloablative HSCT (NM-HSCT), the T-cell receptor excision circle (TREC) content was measured on a weekly ...... hiện toàn bộ
How to narrow down chromosomal breakpoints in small and large derivative chromosomes – a new probe set
Journal of Applied Genetics - Tập 53 Số 3 - Trang 259-269 - 2012
Ahmed B. Hamid, Katharina Kreskowski, Anja Weise, Nadezda Kosayakova, Kristin Mrasek, Martin Voigt, Roberta Santos Guilherme, Ralf Wagner, David Hardekopf, Šoňa Peková, Т. В. Карамышева, Thomas Liehr, Elisabeth Klein
Determination of fatty acid composition in seed oil of rapeseed (Brassica napus L.) by mutated alleles of the FAD3 desaturase genes
Journal of Applied Genetics - Tập 53 - Trang 27-30 - 2011
Jan Bocianowski, Katarzyna Mikołajczyk, Iwona Bartkowiak-Broda
One of the goals in oilseed rape programs is to develop genotypes producing oil with low linolenic acid content (C18:3, ≤3%). Low linolenic mutant lines of canola rapeseed were obtained via chemical mutagenesis at the Plant Breeding and Acclimatization Institute – NRI, in Poznan, Poland, and allele-specific SNP markers were designed for monitoring of two statistically important single nucleotide p...... hiện toàn bộ
Unveiling the putative functional genes present in root-associated endophytic microbiome from maize plant using the shotgun approach
Journal of Applied Genetics - Tập 62 - Trang 339-351 - 2021
Ayomide Emmanuel Fadiji, Ayansina Segun Ayangbenro, Olubukola Oluranti Babalola
To ensure food security for the ever-increasing world’s population, it is important to explore other alternatives for enhancing plant productivity. This study is aimed at identifying the putative plant growth–promoting (PGP) and endophytic gene clusters in root-associated endophytic microbes from maize root and to also verify if their abundance is affected by different farming practices. To achiev...... hiện toàn bộ
Differential expression of candidate genes for lignin biosynthesis under drought stress in maize leaves
Journal of Applied Genetics - Tập 50 - Trang 213-223 - 2009
Y. Hu, W. Ch. Li, Y. Q. Xu, G. J. Li, Y. Liao, F. -L. Fu
In order to provide information for the development of molecular selection markers for drought tolerance improvement, the methods of prometric analysis, quantitative real-time PCR and field evaluation were employed for the identification of the differential expression of candidate genes under drought stress in maize. At seventeen, twenty-four and forty-eight hours of polyethylene glycol-simulated ...... hiện toàn bộ
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