JBIC Journal of Biological Inorganic Chemistry
Công bố khoa học tiêu biểu
* Dữ liệu chỉ mang tính chất tham khảo
Sắp xếp:
Relaxometric characterization of human hemalbumin
JBIC Journal of Biological Inorganic Chemistry - Tập 6 - Trang 650-658 - 2001
Hemalbumin [i.e., Fe(III)-protoporphyrin IX-human serum albumin; Fe(III)heme-HSA] is an important intermediate in the recovery of heme iron following hemolysis. Relaxometric data are consistent with the occurrence of a hexacoordinated high-spin Fe(III) center with no water in the inner coordination sphere. The relatively high relaxation enhancement observed for an aqueous solution of Fe(III)heme-H...... hiện toàn bộ
Native mass spectrometry of human carbonic anhydrase I and its inhibitor complexes
Abstract
Native mass spectrometry is a potent technique to study and characterize biomacromolecules in their native state. Here, we have applied this method to explore the solution chemistry of human carbonic anhydrase I (hCA I) and its interactions with four different inhibitors, namely three sulfonamide inhibitors (AAZ, MZA, SLC-0111) and the dithiocar... ... hiện toàn bộ
JBIC Journal of Biological Inorganic Chemistry - - 2020
Structure and metal binding properties of ZnuA, a periplasmic zinc transporter from Escherichia coli
JBIC Journal of Biological Inorganic Chemistry - Tập 13 - Trang 271-288 - 2007
ZnuA is the periplasmic Zn2+-binding protein associated with the high-affinity ATP-binding cassette ZnuABC transporter from Escherichia coli. Although several structures of ZnuA and its homologs have been determined, details regarding metal ion stoichiometry, affinity, and specificity as well as the mechanism of metal uptake and transfer remain unclear. The crystal structures of E. coli ZnuA (Eco-...... hiện toàn bộ
Sự tương tác của phức hợp quercetin đồng(II) với DNA: cơ chế tiềm năng của các đặc tính chống ung thư của nó Dịch bởi AI
JBIC Journal of Biological Inorganic Chemistry - Tập 14 - Trang 727-739 - 2009
Sự tương tác của phức hợp quercetin đồng(II) với DNA đã được nghiên cứu bằng cách sử dụng quang phổ UV–vis, đo huỳnh quang, đo độ nhớt, điện di gel agarose và xét nghiệm các chất phản ứng với axit thiobarbituric. Kết quả cho thấy phức hợp quercetin đồng(II) có khả năng thúc đẩy sự cắt đứt DNA plasmid, tạo ra các đứt gãy DNA đơn và kép, và xen kẽ vào các cặp base xếp chồng của DNA. Hơn nữa, phức hợ...... hiện toàn bộ
#quercetin #đồng(II) #DNA #tổn thương DNA oxy hóa #hoạt tính chống ung thư #tế bào A549 #apoptosis
A new urolith in four cats and a dog: composition and crystal structure
JBIC Journal of Biological Inorganic Chemistry - Tập 7 - Trang 437-444 - 2001
A previously unreported urolith is presented. The concrement was found in the bladder of four Persian cats and one collie dog. It contained potassium, magnesium and phosphorus, all determined by chemical analysis. The infrared spectrum of the X-ray-dense urolith displayed absorption bands in the phosphate region. A single absorption maximum at 930 cm–1 indicated the presence of inorganic pyrophos...... hiện toàn bộ
Fe–S cluster assembly in the supergroup Excavata
JBIC Journal of Biological Inorganic Chemistry - Tập 23 - Trang 521-541 - 2018
The majority of established model organisms belong to the supergroup Opisthokonta, which includes yeasts and animals. While enlightening, this focus has neglected protists, organisms that represent the bulk of eukaryotic diversity and are often regarded as primitive eukaryotes. One of these is the “supergroup” Excavata, which comprises unicellular flagellates of diverse lifestyles and contains sp...... hiện toàn bộ
Platination of telomeric DNA by cisplatin disrupts recognition by TRF2 and TRF1
JBIC Journal of Biological Inorganic Chemistry - - 2010
Telomeres, the nucleoprotein complexes located at the ends of chromosomes, are involved in chromosome protection and genome stability. Telomeric repeat binding factor 1 (TRF1) and telomeric repeat binding factor 2 (TRF2) are the two telomeric proteins that bind to duplex telomeric DNA through interactions between their C-terminal domain and several guanines of the telomeric tract. Since the antitu...... hiện toàn bộ
Initial step of B12-dependent enzymatic catalysis: energetic implications regarding involvement of the one-electron-reduced form of adenosylcobalamin cofactor
JBIC Journal of Biological Inorganic Chemistry - Tập 17 - Trang 293-300 - 2011
Density functional theory analysis was performed to elucidate the impact of one-electron reduction upon the initial step of adenosylcobalamin-dependent enzymatic catalysis. The transition state (TS) corresponding to the Co–C bond cleavage and subsequent hydrogen abstraction from the substrate was located. The intrinsic reaction coordinate calculations predicted that the reaction consisting of Co–C...... hiện toàn bộ
Structural characterization of the mononuclear iron site in Pseudomonas cepacia phthalate DB01 dioxygenase using X-ray absorption spectroscopy
JBIC Journal of Biological Inorganic Chemistry - Tập 1 - Trang 24-33 - 1996
Phthalate dioxygenase (PDO) from Pseudomonas cepacia contains a Rieske-like [2Fe-2S] cluster and a mononuclear non-heme Fe(II) site. The mononuclear iron can be replaced by a variety of divalent metal ions, although only Fe(II) permits catalytic activity. We used X-ray absorption spectroscopy to characterize the structural properties of the mononuclear iron site and to follow the structural chang...... hiện toàn bộ
Tổng số: 1,971
- 1
- 2
- 3
- 4
- 5
- 6
- 10