Mechanisms of sterile inflammation after intravitreal injection of antiangiogenic drugs: a narrative reviewInternational Journal of Retina and Vitreous - Tập 7 - Trang 1-12 - 2021
William J. Anderson, Natasha Ferreira Santos da Cruz, Luiz Henrique Lima, Geoffrey G. Emerson, Eduardo Büchele Rodrigues, Gustavo Barreto Melo
Intraocular inflammation is an uncommon but potentially vision-threatening adverse event related to anti-VEGF therapy. This is of increasing importance given both the volume of injections performed, as well as the increased prevalence of inflammation seen with newer anti-VEGF agents. Brolucizumab, the newest anti-VEGF agent, has been associated with an inflammatory retinal vasculitis and the under...... hiện toàn bộ
Choroidal thickness in older patients with central serous chorioretinopathyInternational Journal of Retina and Vitreous - Tập 2 - Trang 1-6 - 2016
Caio V. Regatieri, Eduardo A. Novais, Lauren Branchini, Mehreen Adhi, Emily D. Cole, Ricardo Louzada, Mark Lane, Elias Reichel, Jay S. Duker
To investigate the choroidal thickness in older patients with central serous chorioretinopathy (CSCR) compared to age-matched normal subjects. Fifteen patients (30 eyes) with CSCR, all aged ≥60 years, and 21 age-matched normal subjects (21 eyes) underwent high-definition raster scanning using SD-OCT. Both eyes from CSCR patients were included in the analysis. The eyes in patients with CSCR were di...... hiện toàn bộ
Investigation of new dyes for chromovitrectomy: preclinical biocompatibility of trisodium, orangell and methyl violetInternational Journal of Retina and Vitreous - Tập 1 - Trang 1-6 - 2015
Emmerson Badaro, Rodrigo A Souza-Lima, Eduardo A Novais, Mauricio Maia, Flávio Hirai, Carsten H Meyer, Michel Eid Farah, Eduardo B Rodrigues
To investigate the retinal toxicity by electroretinography (ERG), clinical examination and histology after intravitreal injection of biological stains in two concentrations: Trisodium (0.50 g/L and 1.00 g/L), Orangell (0.25 g/L and 1.00 g/L) and Methyl Violet (0.50 g/L and 1.00 g/L). Eighteen New-Zealand albinos rabbits were assigned in six groups (n = 3 in each group). The animals in group 1 rece...... hiện toàn bộ
Aflibercept clearance through the drainage system in a rat modelInternational Journal of Retina and Vitreous - - 2021
Yariv Keshet, Orly Gal-Or, Michal Schaap Fogler, Karin Mimouni, Meydan Ben Ishai, Dov Weinberger, Assaf Dotan
Abstract
Background
As intravitreal anti-VEGF injections became the mainstay of treatment for many retinal diseases, the cause of a secondary sustained elevated intraocular pressure is still unclear. The aim of our study was to study the clearance of Aflibercept from the anterior chamber angle, in a...... hiện toàn bộ
Relationship between retinal vessel tortuosity and oxygenation in sickle cell retinopathyInternational Journal of Retina and Vitreous - Tập 5 - Trang 1-7 - 2019
Maziyar M. Khansari, Sarah L. Garvey, Shayan Farzad, Yonggang Shi, Mahnaz Shahidi
Reduced retinal vascular oxygen (O2) content causes tissue hypoxia and may lead to development of vision-threatening pathologies. Since increased vessel tortuosity is an early sign for some hypoxia-implicated retinopathies, we investigated a relationship between retinal vascular O2 content and vessel tortuosity indices. Dual wavelength retinal oximetry using a commercially available scanning laser...... hiện toàn bộ
Evaluation of the additive effect of interferon α 2b with monthly intravitreal injection of bevacizumab in refractory diabetic macular edemaInternational Journal of Retina and Vitreous - Tập 8 Số 1
Hooshang Faghihi, Bahman Inanloo, Arash Mirzaee, Kaveh Fadakar, Ahmad Mirshahi, Nazanin Ebrahimiadib, Fariba Ghassemi, Fatemeh Bazvand, Abdulrahman Amini, Masoud Mirghorbani, Shahin Faghihi, Elias Khalili Pour, Hamid Riazi-Esfahani
Abstract
Background
To evaluate the additive effect of topical or sub-tenon injection of interferon (IFN)-α 2b in the treatment of refractory diabetic macular edema.
Methods
In this prospect...... hiện toàn bộ
Polymerase chain reaction test for diagnosis of infectious uveitisInternational Journal of Retina and Vitreous - Tập 9 - Trang 1-7 - 2023
Sahba Fekri, Ehsan Barzanouni, Shahram Samiee, Masoud Soheilian
To study the clinical utility of broad-range real-time Polymerase Chain Reaction (PCR) assay in patients suspected for infectious uveitis and to analyze the clinical relevance. Medical records of patients with uveitis were assessed in whom PCR analysis of intraocular fluids was performed between January 2018 and February 2021. Intraocular samples were investigated for cytomegalovirus (CMV), Epstei...... hiện toàn bộ